Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Determinants of inflammatory and immune response in guinea pigs infected with Helicobacter pylori.

2013/09/N/NZ6/00805

Keywords:

Helicobacter pylori inflammmatory response humoral response cellular response cytokines cytotoxicity animal model

Descriptors:

  • NZ6_1: Adaptive and innate immunity
  • NZ6_4: Bacteriology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Eliza Miszczyk 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2014-05-05

Project end date (Y-m-d): 2016-05-04

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (7)
  1. Helicobacter pylori antigens, acetylsalicylic acid, 7-ketocholesterol – a potential role in destabilizing of gastric epithelial cell barrier. Model in vitro of Kato III cells
    Authors:
    Gajewski Adrian, Mnich Eliza, Szymański Karol, Hinc Krzysztof, Obuchowski Michał, Moran A.P, Chmiela Magdalena
    Academic press:
    Acta Biochimica Polonica (rok: 2015, tom: 62, strony: 8), Wydawca: Polskie Towarzystwo Biochemiczne, Komitet Biochemii i Biofizyki PAN
    Status:
    Published
    DOI:
    10.18388/abp.2015_1122 - link to the publication
  2. Impact of Helicobacter pylori on the healing process of the gastric barrier
    Authors:
    Mnich Eliza, Kowalewicz-Kulbat Magdalena, Sicińska Paulina, Hinc Krzysztof, Obuchowski Michał, Gajewski Adrian, Moran Anthony P, Chmiela Magdalena
    Academic press:
    World Journal of Gastroenterology (rok: 2016, tom: 22, strony: 7536-7558), Wydawca: Baishideng publishing Group
    Status:
    Published
    DOI:
    10.3748/wjg.v22.i33.7536 - link to the publication
  3. Structural modifications of Helicobacter pylori lipopolysaccharide: an idea for how to live in peace
    Authors:
    Chmiela Magdalena, Miszczyk Eliza, Rudnicka Karolina
    Academic press:
    World Journal of Gastroenterology (rok: 2014, tom: 20, strony: 9882-9897), Wydawca: Baishideng Publishing Group
    Status:
    Published
    DOI:
    10.3748/wjg.v20.i29.9882 - link to the publication
  4. The microbiological, histological, serological and molecular determinants of Helicobacter pylori infection in guinea pigs as a convenient animal model to study pathogenicity of these bacteria and the infection dependent immune response of the host
    Authors:
    Walencka Maria, Gonciarz Weronika, Mnich Eliza, Gajewski Adrian, Chmiela Magdalena
    Academic press:
    Acta Biochimica Polonica (rok: 2015, tom: 62, strony: 10), Wydawca: Polskie Towarzystwo Biochemiczne, Komitet Biochemii i Biofizyki PAN
    Status:
    Published
    DOI:
    10.18388/abp.2015_1110 - link to the publication
  5. Antigen-specific proliferation as a marker of immune response in guinea pigs with sustained Helicobacter pylori infection
    Authors:
    Miszczyk Eliza, Walencka Maria, Rudnicka Karolina, Matusiak Agnieszka, Rudnicka Wiesława, Chmiela Magdalena
    Academic press:
    Acta Biochimica Polonica (rok: 2014, tom: 61, strony: 295-303), Wydawca: Polskie Towarzystwo Biochemiczne, Komitet Biochemii i Biofizyki PAN
    Status:
    Published
  6. Immunoregulation of antigen presenting and secretory functions of monocytic cells by Helicobacter pylori antigens in relation to impairment of lymphocyte expansion
    Authors:
    Mnich Eliza, Gajewski Adrian, Rudnicka Karolina, Gonciarz Weronika, Stawerski Paweł, Hinc Krzysztof, Obuchowski Michał, Chmiela Magdalena
    Academic press:
    Acta Biochimica Polonica (rok: 2015, tom: 62, strony: 10), Wydawca: Polskie Towarzystwo Biochemiczne, Komitet Biochemii i Biofizyki PAN
    Status:
    Published
    DOI:
    10.18388/abp.2015_1045 - link to the publication
  7. Modele zwierzęce w badaniach nad przebiegiem zakażeń Helicobacter pylori
    Authors:
    Miszczyk Eliza, Walencka Maria, Chmiela Magdalena
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (rok: 2014, tom: 68, strony: 603-615), Wydawca: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/17322693.1102583 - link to the publication