Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Three-dimensional hybrid biomaterials doped with magnetic nanoparticles for thermal apoptosis of cancer cells and attached growth factor for osteoblasts

2013/09/D/ST8/03995

Keywords:

hydroxyapatite scaffold bone tissue engineering composites mechanical properties biomineralization in vitro studies degradation growth factors magnetic particles

Descriptors:

  • ST8_8: Mechanics of solids

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Uniwersytet Wrocławski, Wydział Chemii

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Łukasz John 

Number of co-investigators in the project: 6

Call: SONATA 5 - announced on 2013-03-15

Amount awarded: 348 000 PLN

Project start date (Y-m-d): 2014-02-10

Project end date (Y-m-d): 2017-02-09

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (8)
  1. Novel organic-inorganic hybrids based on T8 and T10 silsesquioxanes: synthesis, cage-rearrangement and properties.
    Authors:
    Mateusz Janeta, Łukasz John, Jolanta Ejfler, Sławomir Szafert
    Academic press:
    RSC Advances (rok: 2015, tom: 5, strony: 72340-72351), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c5ra10136k - link to the publication
  2. Synthesis and Microstructural Properties of the Scaffold Based on a 3-(Trimethoxysilyl)propyl Methacrylate-POSS Hybrid Towards Potential Tissue Engineering Applications
    Authors:
    Łukasz John*, Mateusz Janeta, Magdalena Rajczakowska, Jolanta Ejfler, Dariusz Łydżba, Sławomir Szafert
    Academic press:
    RSC Avances (rok: 2016, tom: 6, strony: 66037-66047), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C6RA10364B - link to the publication
  3. First Step Towards a Model System of the Drug Delivery Network Based on Amide-POSS Nanocarriers
    Authors:
    Łukasz John*, Mariola Malik, Mateusz Janeta, Sławomir Szafert
    Academic press:
    RSC Advances (rok: 2017, tom: 7, strony: 8394-8401), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c6ra26330e - link to the publication
  4. High-Yield Synthesis of Amido-Functionalized Polyoctahedral Oligomeric Silsesquioxanes by Using Acyl Chlorides.
    Authors:
    Mateusz Janeta, Łukasz John*, Jolanta Ejfler, Sławomir Szafert
    Academic press:
    Chemistry - A European Journal (rok: 2014, tom: 20, strony: 15966-15974), Wydawca: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
    Status:
    Published
    DOI:
    10.1002/chem.201404153 - link to the publication
  5. Designing of Macroporous Magnetic Bioscaffold Based on Functionalized Methacrylate Network Covered by Hydroxyapatites and Doped with Nano-MgFe2O4 for Potential Cancer Hyperthermia Therapy
    Authors:
    Łukasz John*, Mateusz Janeta, Sławomir Szafert
    Academic press:
    Materials Science and Engineering C (rok: 2017, tom: -, strony: -), Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    Brak - link to the publication
  6. Strontium-Doped Organic-Inorganic Hybrids Towards Three-Dimensional Scaffolds for Osteogenic Cells
    Authors:
    Łukasz John*, Marta Podgórska, Jean-Marie Nedelec, Łucja Cwynar-Zając, Piotr Dzięgiel
    Academic press:
    Materials Science and Egineering C (rok: 2016, tom: 68, strony: 117-127), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2016.05.105 - link to the publication
  7. Multifunctional Imine-POSS as Uncommon 3D Nanobuilding Blocks for Supramolecular Hybrid Materials: Synthesis, Structural Characterization, and Properties
    Authors:
    Mateusz Janeta, Łukasz John*, Jolanta Ejfler, Tadeusz Lis, Sławomir Szafert
    Academic press:
    Dalton Transactions (rok: 2016, tom: 45, strony: 12312-12321), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C6DT02134D - link to the publication
  1. High-yield synthesis of amido-functionalized polyoctahedral oligomeric silsesquioxanes using acyl chlorides.
    Authors:
    Łukasz John, Mateusz Janeta
    Conference:
    Fourth International Conference on Multifunctional, Hybrid and Nanomaterials (rok: 2015, ), Wydawca: Elsevier
    Data:
    konferencja 9-13 March
    Status:
    Published
  2. Novel organic-inorganic hybrids based on oligomeric T8 and T10 silsesquioxanes
    Authors:
    Łukasz John, Mateusz Janeta, Jolanta Ejfler, Sławomir Szafert
    Conference:
    16th POC - International Conference on Polymers & Organic Chemistry (rok: 2016, ), Wydawca: University of Crete, Greece
    Data:
    konferencja 13-16 June
    Status:
    Published
  3. Funkcjonalizowanie klatkowych silseskwioksanów.
    Authors:
    Mariola Malik, Mateusz Janeta, Łukasz John, Jolanta Ejfler, Sławomir Szafert
    Conference:
    VI Wrocławskie Studenckie Sympozjum Chemiczne (rok: 2015, ), Wydawca: Politechnika Wrocławska
    Data:
    konferencja 16-17 maja
    Status:
    Published
  4. Funkcjonalizowanie klatkowych silseskwioksanów.
    Authors:
    Mariola Malik, Mateusz Janeta, Łukasz John, Jolanta Ejfler, Sławomir Szafert
    Conference:
    Zjazd Zimowy Sekcji Studenckiej Polskiego Towarzystwa Chemicznego, Kraków (rok: 2015, ), Wydawca: Polskie Towarzystwo Chemiczne
    Data:
    konferencja 5 grudnia
    Status:
    Published
  5. Non-Cytotoxic Strontium Doped Biocomposites for Guided Bone Regeneration
    Authors:
    Marta Bałtrukiewicz, Łukasz John, Piotr Sobota
    Conference:
    XV International Seminar of PhD-Students on Organometallic and Coordination Chemistry (rok: 2014, ), Wydawca: Wydział Chemii Uniwersytetu Wrocławskiego i Wydział Chemiczny Politechniki Warszawskiej
    Data:
    konferencja 5-9 kwietnia
    Status:
    Published
  6. Functionalized Polyhedral Oligomeric Silsesquioxanes as Precursors for Novel Hybrid Materials
    Authors:
    Łukasz John*, Mateusz Janeta, Sławomir Szafert
    Conference:
    EUPOC 2014 Precision Polymers: Synthesis, Folding and Function (rok: 2014, ), Wydawca: European Polymer Federation
    Data:
    konferencja 25-29 maja
    Status:
    Published
  7. Interdyscyplinarne oblicza związków krzemu: od tlenków, poprzez organiczno-nieorganiczne kompozyty, do klatkowych silseskwioksanów.
    Authors:
    Łukasz John
    Conference:
    II Ogólnopolskie SympozjumInterdyscyplinarne Inter-Mix 2014 (http://inter-mix2014.klub-fnp.pl/) (rok: 2014, ), Wydawca: Klub Stypendystów Fundacji na rzecz Nauki Polskiej (FNP)
    Data:
    konferencja 20-23 listopada
    Status:
    Published
  8. Synthesis and Characterization of Novel Nanosized Hyperbranched Polyhedral Oligomeric Silsesquioxanes
    Authors:
    Mateusz Janeta, Łukasz John*, Sławomir Szafert
    Conference:
    XV International Seminar of PhD-Students on Organometallic and Coordination Chemistry (rok: 2014, ), Wydawca: Wydział Chemii Uniwersytetu Wrocławskiego i Wydział Chemiczny Politechniki Warszawskiej
    Data:
    konferencja 5-9 kwietnia
    Status:
    Published

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