Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Studying phosphorus dendrimers as system transporting photosensitizers

2013/08/M/NZ1/00761

Keywords:

dendrimer nanomedicine photosensitizer photodynamic therapy PDT cancer

Descriptors:

  • NZ1_3: Biophysics
  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • ST5_21:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Barbara Klajnert-Maculewicz 

Number of co-investigators in the project: 7

Call: HARMONIA 4 - announced on 2012-12-15

Amount awarded: 695 760 PLN

Project start date (Y-m-d): 2013-10-02

Project end date (Y-m-d): 2016-10-01

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (6)
  1. Fourier transform infrared spectroscopy (FTIR) characterization of the interaction of anti-cancer photosensitizers with dendrimers
    Authors:
    M. Dąbrzalska, N. Benseny-Cases, R. Barnadas-Rodriguez, S. Mignani, M. Zabłocka, J. P. Majoral, M. Bryszewska, B. Klajnert-Maculewicz
    Academic press:
    Analytical and Bioanalytical Chemistry (rok: 2016, tom: 408, strony: 535-544), Wydawca: Springer Heidelberg
    Status:
    Published
    DOI:
    10.1007/s00216-015-91250 - link to the publication
  2. Complexing methylene blue with phosphorus dendrimers to increase photodynamic activity
    Authors:
    122)M. Dabrzalska, A. Janaszewska, M. Zablocka, S. Mignani, J. P., Majoral, B. Klajnert-Maculewicz
    Academic press:
    Molecules (rok: 2017, tom: 22, strony: 345-358), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules22030345 - link to the publication
  3. Cationic phosphorus dendrimer enhances photodynamic activity of rose bengal against basal cell carcinoma cell lines
    Authors:
    124)M. Dabrzalska, A. Janaszewska, M. Zablocka, S. Mignani, J. P. Majoral, B. Klajnert-Maculewicz
    Academic press:
    Molecular Pharmaceutics (rok: 2017, tom: 14, strony: 1821-1830), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.molpharmaceut.7b00108 - link to the publication
  4. Phosphorus dendrimers and photodynamic therapy. Spectroscopic studies on two dendrimer-photosensitizer complexes: cationic phosphorus dendrimer with rose bengal and anionic phosphorus dendrimer with methylene blue
    Authors:
    M. Dąbrzalska, M. Zabłocka, S. Mignani, J. P. Majoral, B. Klajnert-Maculewicz
    Academic press:
    International Journal of Chemistry (rok: 2015, tom: 492, strony: 266-274), Wydawca: Elsevier Science BV
    Status:
    Published
    DOI:
    10.1016/j.iparm.2015.06.014 - link to the publication
  1. Phosphorus dendrimers as carriers of photosensitizers
    Authors:
    B. Klajnert-Maculewicz, M. Dabrzalska, A. Janaszewska, M. Zablocka, S. Mignani, J.P. Majoral
    Conference:
    5th International Symnposium on Biomedical Applications of Dendrimers (rok: 2016, ), Wydawca: University of Copenhagen
    Data:
    konferencja 2-5 sierpnia 2016
    Status:
    Published
  2. Phosphorus dendrimers in photodynamic therapy
    Authors:
    B. Klajnert-Maculewicz, M. Dabrzalska, A. Janaszewska, M. Zablocka, S. Mignani, J.P. Majoral
    Conference:
    European & Global Summit for Cutting-Edge Medicine (rok: 2016, ), Wydawca: CLINAM
    Data:
    konferencja 26-19 czerwca 2016
    Status:
    Published
  3. Phosphorus dendrimers: potential nanocarriers in photodynamic therapy. Formation of the complexes and their in vivo activity in basal carcinoma cell lines.
    Authors:
    M. Dąbrzalska, A. Janaszewska, N. Benseny-Cases, R. Barnadas, J. Cladera, S. Mignani, M. Zabłocka, J. P. Majoral, M. Bryszewska, B. Klajnert-Maculewicz
    Conference:
    8th European CLINAM Conference. THe European Summit for Clinical Nanomedicine and Targeted Medicine (rok: 2015, ), Wydawca: Conference Proceedings
    Data:
    konferencja 28 czerwca - 1 lipca 2015
    Status:
    Published
  4. Spectroscopic study on the interaction of phosphorus dendrimers and photosensitizers
    Authors:
    M. Dąbrzalska, M. Bryszewska, B. Klajnert-Maculewicz
    Conference:
    1st International Symposium on Nanoparticles/nanomaterials and Applications (rok: 2014, ), Wydawca: Proceedings
    Data:
    konferencja 20-22 stycznia 2014
    Status:
    Published
  5. In vitro evaluation of photodynamic activity of dendrimer-photosensitizer complexes
    Authors:
    M. Dąbrzalska, A. Janaszewska, J. P. Majoral, B. Klajnert-Maculewicz, M. Bryszewska
    Conference:
    4th International Symposium on Biomedical Applications of Dendrimers (rok: 2014, ), Wydawca: Book of Abstracts
    Data:
    konferencja 18-20 czerwca 2014
    Status:
    Published
  6. Dendrimer-photosensitizer complexes: Spectroscopic characterization and photodynamic activity in vitro on basel carcinoma cell lines
    Authors:
    M. Dąbrzalska, A. Janaszewska, N. Benseny-Cases, R. Barnadas, J. Cladera, S. Mignani, M. Zabłocka, J. P. Majoral, M. Bryszewska, B. Klajnert-Maculewicz
    Conference:
    The American Society for Nanomedicine (ASNM) 5th Annual International Conference (rok: 2015, ), Wydawca: Abstracts
    Data:
    konferencja 15-17 października 2015
    Status:
    Published