Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Study of interaction and signal passing in complexes of GPCRs with arrestin

2013/08/M/ST6/00788

Keywords:

GPCRs arrestin inactivation signal transmission

Descriptors:

  • ST6_13: Bioinformatics, biocomputing, DNA and molecular computation
  • ST6_12: Scientific computing, simulation and modelling tools

Panel:

ST6 - Computer science and informatics: informatics and information systems, computer science, scientific computing, intelligent systems

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Sławomir Filipek 

Number of co-investigators in the project: 5

Call: HARMONIA 4 - announced on 2012-12-15

Amount awarded: 537 960 PLN

Project start date (Y-m-d): 2013-09-03

Project end date (Y-m-d): 2016-09-02

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  1. The principles of ligand specificity on beta-2-adrenergic receptor
    Authors:
    H.C.S. Chan, S. Filipek, S. Yuan
    Academic press:
    Scientific Reports - Nature (rok: 2016, tom: 6, strony: 34736), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/srep34736 - link to the publication
  2. Exploring a new ligand binding site of G protein-coupled receptors
    Authors:
    H.C.S Chan, J. Wang, K. Palczewski, S. Filipek, H. Vogel, Z.J. Liu, S. Yuan
    Academic press:
    Chemical Science (rok: 2018, ), Wydawca: Royal Society of Chemistry
    Status:
    Accepted for publication
    DOI:
    10.1039/c8sc01680a - link to the publication
  3. Mechanistic studies on the stereoselectivity of the serotonin 5-HT1A receptor
    Authors:
    S. Yuan, Q. Peng, K. Palczewski, H. Vogel, S. Filipek
    Academic press:
    Angew. Chem. Int. Ed. (rok: 2016, tom: 55, strony: 8661-8665), Wydawca: Wiley-VCH Verlag GmbH
    Status:
    Published
    DOI:
    10.1002/anie.201603766 - link to the publication