Role of astrocytic NMDA receptors in ammonia-induced brain edema associated with hepatic encephalopathy.
2013/08/M/NZ3/00869
Keywords
Descriptors
- NZ3_6: Neurobiologia komórkowa
- NZ3_2: Fizjologia komórki
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 7
Call
HARMONIA 4 – announced on 2012-12-15
- Amount awarded
- 935 000 PLN
- Project start date
- 2013-08-29
- Project end date
- 2017-02-28
- Project duration
- 42 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (4)
-
Interstitial ion homeostasis and acid-base balance are maintained in oedematous brain of mice with acute toxic liver failure
- Authors:
- Marta Obara-Michlewska, Fengfei Ding, Mariusz Popek, Alexei Verkhratsky,Maiken Nedergaard, Magdalena Zielinska, Jan Albrecht
- Academic press:
- Neurochemistry International (year: 2018, volume: 118, pages: 286-291), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.neuint.2018.05.007 – link to the publication
-
Astroglial NMDA receptors inhibit expression of Kir4.1 channels in glutamate-overexposed astrocytes in vitro and in the brain of rats with acute liver failure.
- Authors:
- Marta Obara-Michlewska, Joanna Ruszkiewicz, Magdalena Zielińska, Alexei Verkhratsky, Jan Albrecht
- Academic press:
- Neurochemistry International (year: 2014, volume: xxx, pages: xxx), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.neuint.2014.10.006 – link to the publication
-
Persistentoverexposure to N-methyl-D-aspartate (NMDA) calcium-dependentlydownregulatesglutaminesynthetase, aquaporin 4 and Kir4.1 channel in mousecorticalastrocytes.
- Authors:
- Katarzyna Skowrońska, Marta Obara-Michlewska, Anna Czarnecka, Katarzyna Dąbrowska, Magdalena Zielińska, and Jan Albrecht
- Academic press:
- Neurotoxicity Research (year: 2019, volume: 35, pages: 271–280), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s12640-018-9958-3 – link to the publication
-
NMDA Receptors in Astrocytes: In Search for Roles in Neurotransmission and Astrocytic Homeostasis.
- Authors:
- Katarzyna Skowrońska, Marta Obara-Michlewska, Magdalena Zielińska, Jan Albrecht
- Academic press:
- International Journal of Molecular Sciences (year: 2019, volume: 20, pages: 309), Publisher: MDPI (Basel)
- Status:
- Published
- DOI:
- 10.3390/ijms20020309 – link to the publication
Book publications / chapters in book publications (1)
-
Physiology of Astroglia: Channels, Receptors, Transporters, Ion Signaling and Gliotransmission
- Authors:
- Verkhratsky A. Parpura V
- Book:
- COLLOQUIUM SERIES ON NEUROGLIA IN BIOLOGY AND MEDICINE: FROM PHYSIOLOGY TO DISEASE (year: 2015, volume: vol 1, pages: 1-155), Publisher: Morgan & Claypool
- Status:
- Published