Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Peptydazy kodowane przez genom bakterii z gatunku Tannerella forsythia.

2013/08/T/NZ1/00315

Keywords:

Descriptors:

  • NZ1_2: Biochemistry
  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Mirosław Książek 

Number of co-investigators in the project: 2

Call: ETIUDA 1 - announced on 2012-12-15

Amount awarded: 98 702 PLN

Project start date (Y-m-d): 2013-10-01

Project end date (Y-m-d): 2014-09-30

Project duration:: 12 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (6)
  1. Purification and characterisation of recombinant His-tagged RgpB gingipain from Porphymonas gingivalis.
    Authors:
    Veillard F, Potempa B, Guo Y, Ksiazek M, Sztukowska MN, Houston JA, Koneru L, Nguyen KA, Potempa J.
    Academic press:
    Biological Chemistry (rok: 2015, tom: 396(4), strony: 377-84), Wydawca: De Gruyter
    Status:
    Published
    DOI:
    10.1515/hsz-2014-0304 - link to the publication
  2. A novel mechanism of latency in matrix metalloproteinases.
    Authors:
    López-Pelegrín M, Ksiazek M, Karim AY, Guevara T, Arolas JL, Potempa J, Gomis-Rüth FX
    Academic press:
    Journal of Biological Chemistry (rok: 2015, tom: 290(8), strony: 4728-40), Wydawca: American Society for Biochemistry and Molecular Biology
    Status:
    Published
    DOI:
    10.1074/jbc.M114.605956 - link to the publication
  3. Miropin, a novel bacterial serpin from the periodontopathogen Tannerella forsythia, inhibits a broad range of proteases by using different peptide bonds within the reactive center loop
    Authors:
    Ksiazek M, Mizgalska D, Enghild JJ, Scavenius C, Thogersen IB, Potempa J
    Academic press:
    Journal of Biological Chemistry (rok: 2015, tom: 290(1), strony: 658-70), Wydawca: American Society for Biochemistry and Molecular Biology
    Status:
    Published
    DOI:
    10.1074/jbc.M114.601716 - link to the publication
  4. A metalloproteinase mirolysin of Tannerella forsythia inhibits all pathways of the complement system.
    Authors:
    Jusko M, Potempa J, Mizgalska D, Bielecka E, Ksiazek M, Riesbeck K, Garred P, Eick S, Blom AM.
    Academic press:
    Journal of Immunology (rok: 2015, tom: nie dotyczy, strony: nie dotyczy), Wydawca: American Association of Immunologists
    Status:
    Accepted for publication
  5. KLIKK proteases of Tannerella forsythia: putative virulence factors with a unique domain structure.
    Authors:
    Ksiazek M, Mizgalska D, Eick S, Thøgersen IB, Enghild JJ, Potempa J.
    Academic press:
    Frontiers in Microbiology (rok: 2015, tom: 0,466666666666667, strony: nie dotyczy), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmicb.2015.00312 - link to the publication
  6. Mirolase, a novel subtilisin-like serine protease from the periodontopathogen Tannerella forsythia
    Authors:
    Ksiazek M, Karim AY, Bryzek D, Enghild JJ, Thøgersen IB, Koziel J, Potempa J
    Academic press:
    Biological Chemistry (rok: 2015, tom: 396(3), strony: 261-75), Wydawca: De Gruyter
    Status:
    Published
    DOI:
    10.1515/hsz-2014-0256 - link to the publication