Projects funded by the NCN
Interactions of U6 snRNA within the catalytic center of the spliceosome – modulation of pre-mRNA splicing by U6-like exon sequences.
2013/08/A/NZ1/00167
Keywords:
pre-mRNA splicing splicesome U6 snRNA exon enhancers
Descriptors:
- NZ2_1: Molecular genetics
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 5
Call: MAESTRO 4 - announced on 2012-12-15
Amount awarded: 2 998 848 PLN
Project start date (Y-m-d): 2013-09-23
Project end date (Y-m-d): 2020-08-22
Project duration:: 83 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Aparat do elektroforezy pionowej.
- Elektroporator.
- Inkubator z chłodzeniem (2 sztuki).
- Komputery.
- Spektrofotometr ND1000 (34 000 PLN)
- Wirowka stolowa Rottina 35 z rotorem (35 000 PLN)
- Radiometr.
- Termocykler z gradientem temperatur Biometra do prowadzenia reakcji PCR (36 000 PLN)
- Zasilacz do elektroforezy z wyposazeniem (28 000 PLN)
- Cieplarka mikrobiologiczna.
- Termoblok z wytrząsaniem.
- Wirowki stolowe typu Eppendorf z rotorem (2 szt.) (28 000 PLN)
- Wytrząsarka Innova 42 bez chłodzenia.
Information in the final report
- Publication in academic press/journals (1)
- Rearrangements within the U6 snRNA core during the transition between the two catalytic steps of splicingAuthors:Eysmont K., Matylla-Kulińska K., Jaskulska A., Magnus M., and Konarska MM.Academic press:Molecular Cell (rok: 2019, tom: 75(3), strony: 538-548), Wydawca: Cell PressStatus:PublishedDOI:10.1016/j.molcel.2019.05.018 - link to the publication