Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Proteomic patterns in classification of thyroid cancer

2012/07/B/NZ4/01450

Keywords:

proteomics mass spectrometry thyroid cancer molecular imaging molecular pathology

Descriptors:

  • NZ4_5: Anatomical pathology
  • NZ4_6: Endocrinology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie Oddział w Gliwicach

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Piotr Widłak 

Number of co-investigators in the project: 8

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 598 600 PLN

Project start date (Y-m-d): 2013-07-09

Project end date (Y-m-d): 2017-07-08

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Dysk pamięci (565 PLN)
  2. brak mozliwosci usuniecia rekordu.
  3. Komputer przenośny.
  4. Laser DPSS do spektrometru MALDI.
  5. Cieplarka laboratoryjna (2 693 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. Application of metabolomics in thyroid cancer research
    Authors:
    Wojakowska A, Chekan M, Widłak P, Pietrowska M
    Academic press:
    Int J Endocrinol (rok: 2015, tom: 2015, strony: 258763), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2015/258763 - link to the publication
  2. An optimized method of metabolite extraction from formalin-fixed paraffin-embedded tissue for GC/MS analysis
    Authors:
    Wojakowska A, Marczak Ł, Jelonek K, Polanski K, Widlak P, Pietrowska M
    Academic press:
    PLoS One (rok: 2015, tom: 10(9), strony: e0136902), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0136902 - link to the publication
  3. Detection of metabolites discriminating subtypes of thyroid cancer: molecular profiling of FFPE samples using the GC/MS approach
    Authors:
    Wojakowska A, Chekan M, Marczak Ł, Polanski K, Lange D, Pietrowska M, Widlak P
    Academic press:
    Mol Cell Endocrinol (rok: 2015, tom: 417, strony: 149-157), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.mce.2015.09.021 - link to the publication
  4. Discrimination of papillary thyroid cancer from non-cancerous thyroid tissue based on lipid profiling by MALDI-MSI
    Authors:
    Wojakowska A, Cole LM, Chekan M, Bednarczyk K, Maksymiak M, Oczko-Wojciechowska M, Jarzab B, Clench MR, Polanska J, Pietrowska M, Widlak P
    Academic press:
    Polish Journal of Endocrynology (rok: 2018, tom: 69, strony: 45330), Wydawca: Via Medica Journals
    Status:
    Published
    DOI:
    10.5603/EP.a2018.0003 - link to the publication
  5. Molecular profiles of thyroid cancer subtypes: Classification based on features of tissue revealed by mass spectrometry imaging
    Authors:
    Pietrowska M, Diehl HC, Mrukwa G, Kalinowska-Herok M, Gawin M, Chekan M, Elm J, Drazek G, Krawczyk A, Lange D, Meyer HE, Polanska J, Henkel C, Widlak P
    Academic press:
    Biochimica et Biophysica Acta - Proteins and Proteomics (rok: 2017, tom: 1865, strony: 837-845), Wydawca: Elsevier
    Status:
    Published
  6. Proteome profiles of diffrent types of thyroid cancers
    Authors:
    Gawin M, Wojakowska A, Pietrowska M, Marczak L, Chekan M, Jelonek K, Jaksik R, Gruca A, Widlak P
    Academic press:
    Molecular and Cellular Endocrinology (rok: 2018, tom: 472, strony: 68-79), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.mce.2017.11.020 - link to the publication