Applications of vibrational spectroscopy and femtosecond spectroscopy in oncological diagnostics of human breast.
2012/07/B/ST4/01588
Keywords
Descriptors
- ST4_3: Metody spektroskopowe i spektrometryczne
- ST4_8: Metody instrumentalne w chemii
- ST4_13: Chemia fizyczna układów biologicznych
Panel
ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution
Politechnika Łódzka, Wydział Chemiczny
Voivodeship: łódzkie
Principal investigator (from the host institution)
Number of co-investigators in the project: 8
Call
OPUS 4 – announced on 2012-09-15
- Amount awarded
- 840 000 PLN
- Project start date
- 2013-07-22
- Project end date
- 2016-07-21
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Laser pompujący wzmacniacz w femtosekundowym układzie laserowym.. Cost: 470 000 PLN
Information in the final report
Publication in academic press/journals (9)
-
Oncologic photodynamic diagnosis and therapy: confocal Raman/fluorescence imaging of metal phthalocyanines in human breast cancer tissue in vitro
- Authors:
- Halina Abramczyk, Beata Brozek-Pluska, Jakub Surmacki, Jacek Musial and Radzislaw Kordek
- Academic press:
- Analyst (year: 2014, volume: 139, pages: 5547-5559), Publisher: Royal Chemical Society
- Status:
- Published
- DOI:
- 10.1039/C4AN00966E – link to the publication
-
New look inside human breast ducts with Raman imaging. Raman candidates as diagnostic markers for breast cancer prognosis: Mammaglobin, palmitic acid and sphingomyelin
- Authors:
- Halina Abramczyk, Beata Brozek-Pluska
- Academic press:
- Analytica Chimica Acta (year: 2016, volume: 909, pages: 91-100), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.aca.2015.12.038 – link to the publication
-
Epigenetic changes in cancer by Raman imaging, fluorescence imaging, AFM and scanning near-field optical (SNOM). Acetylation in normal and human cancer breast cells MCF10A, MCF7 and MDA-MB-231
- Authors:
- H. Abramczyk, J. Surmacki, M. Kopec, A.K. Olejnik, A. Kaufman-Szymczyk, K. Fabianowska-Majewska
- Academic press:
- Analyst (year: 2016, volume: 141(19), pages: 5646-58), Publisher: RCS-Royal Society of Chemistry
- Status:
- Published
- DOI:
- 10.1039/C6AN00859C – link to the publication
-
Raman microspectroscopy of Hematoporphyrins. Imaging of the noncancerous and the cancerous human breast tissues with photosensitizers.
- Authors:
- Brozek-Pluska B, Kopec M
- Academic press:
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (year: 2016, volume: 169, pages: 182–191), Publisher: Elsvier
- Status:
- Published
- DOI:
- 10.1016/j.saa.2016.06.038 – link to the publication
-
The lipid-reactive oxygen species phenotype of breast cancer. Raman spectroscopy and mapping, PCA and PLSDA for invasive ductal carcinoma and invasive lobular carcinoma. Molecular tumorigenic mechanisms beyond Warburg effect
- Authors:
- Jakub Surmacki, Beata Brozek-Pluska, Radzislaw Kordek and Halina Abramczyk
- Academic press:
- Analyst (year: 2015, volume: 140, pages: 2121-2133), Publisher: Royal Chemical Society
- Status:
- Published
- DOI:
- 10.1039/C4AN01876A – link to the publication
-
The role of lipid droplets and adipocytes in cancer. Raman imaging of cell cultures: MCF10A, MCF7, and MDA-MB-231 compared to adipocytes in cancerous human breast tissue
- Authors:
- Halina Abramczyk, Jakub Surmacki, Monika Kopeć, Alicja Klaudia Olejnik, Katarzyna Lubecka-Pietruszewska and Krystyna Fabianowska-Majewska
- Academic press:
- Analyst (year: 2015, volume: 140, pages: 2224-2235), Publisher: Royal Chemical Society
- Status:
- Published
- DOI:
- 10.1039/C4AN01875C – link to the publication
-
Raman microspectroscopy of noncancerous and cancerous human breast tissues. Identification and phase transitions of linoleic and oleic acids by Raman low-temperature studies
- Authors:
- Beata Brozek-Pluska, Monika Kopec, Jakub Surmacki and Halina Abramczyk
- Academic press:
- Analyst (year: 2015, volume: 140, pages: 2134-2143), Publisher: Royal Chemical Society
- Status:
- Published
- DOI:
- 10.1039/C4AN01877J – link to the publication
-
The cellular environment of cancerous human tissue. Interfacial and dangling water as a hydration fingerprint
- Authors:
- Abramczyk H, Brozek-Pluska B, Krzesniak M, Kopec M, Morawiec-Sztandera A.
- Academic press:
- Spectrochim Acta A Mol Biomol Spectrosc (year: 2014, volume: 129, pages: 609-23), Publisher: Elsevier B.V
- Status:
- Published
- DOI:
- 10.1016/j.saa.2014.03.103 – link to the publication
-
Photostability of Biological Systems - Femtosecond Dynamics of Zinc Tetrasulfonated Phthalocyanine at Cancerous and Noncancerous Human Breast Tissues
- Authors:
- H. Abramczyk, B. Brozek-Pluska, M. Tondusson, E. Freysz
- Academic press:
- Journal of Photochemistry & Photobiology, A: Chemistry (year: 2017, volume: 332, pages: 46319), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.jphotochem.2016.08.012 – link to the publication
Articles in post-conference publications (15)
-
Obrazowanie Ramana i technika SERS w analizie tkanek i linii komórkowych ludzkiego gruczołu piersiowego
- Authors:
- B. Brożek-Płuska, J. Surmacki, M. Kopeć, H. Abramczyk
- Conference:
- Seminarium Na granicy powierzchni i światła: Adsorpcja i spektroskopia SERS (year: 2015, pages: 18-19), Publisher: UJ, Polska
- Date:
- conference 02-03.07
- Status:
- Published
-
Hope and Innovative Cancer Diagnostics by Raman,
- Authors:
- H. Abramczyk, M. Kopeć, B. Brożek-Płuska
- Conference:
- 12th confocal Raman Imaging Symposium, (year: 2015, pages: 1), Publisher: WITec GmbH, Germany
- Date:
- conference 28-30.09
- Status:
- Published
-
Obrazowanie ramanowskie w mikroskali-od pojedynczej komórki do tkanki,
- Authors:
- Monika Kopeć, Beata Brożek-Płuska, Jakub Surmacki, Halina Abramczyk
- Conference:
- II Poznańskie Sympozjum młodych Naukowców. Nowe Oblicze Nauk Przyrodniczych (year: 2015, pages: 103), Publisher: Wydział Chemii UAM
- Date:
- conference 14,11
- Status:
- Published
-
Zastosowanie obrazowania ramanowskiego w analizie układów biologicznych.
- Authors:
- Monika Kopeć, Halina Abramczyk
- Conference:
- Mała Wielka Nauka, mikro, nano i co dalej? (year: 2014, pages: SO1_P_42), Publisher: Politechnika Łódzka
- Date:
- conference 4-5.12
- Status:
- Published
- DOI:
- link to the publication
-
Wielonienasycone kwasy tłuszczowe jako czynniki modyfikujące procesy nowotworowe
- Authors:
- Monika Kopeć, Beata Brożek-Płuska, Jakub Surmacki, Halina Abramczyk
- Conference:
- III Łódzkie Sympozjum Doktorantów Chemii (year: 2015, pages: 59), Publisher: Wydział Chemii UŁ
- Date:
- conference 27-28.04
- Status:
- Published
-
The application of Raman imaging in the analysis of biological systems, ,,
- Authors:
- Monika Kopeć, Halina Abramczyk
- Conference:
- V Wyjazdowa Sesja Naukowa Doktorantów Politechniki Łódzkiej (year: 2015, pages: P-17), Publisher: Wydział Chemiczny PŁ
- Date:
- conference 9-12.04
- Status:
- Published
-
Raman spectroscopy and imaging of human breast tissues and cel lines-optical imaging technologies in medical applications
- Authors:
- B. Brożek-Płuska, J. Surmacki, M. Kopeć, J. Musiał, R. Kordek, H. Abramczyk,
- Conference:
- Advanced Vibrational Spectroscopy for Biomedical Applications (year: 2016, pages: 1), Publisher: St Catherine's College, Cambridge, UK
- Date:
- conference 21-23. 03.2016 r
- Status:
- Published
-
Hope and Innovative Cancer Diagnostic by Raman Imaging,
- Authors:
- M. Kopeć, H. Abramczyk
- Conference:
- VI Wyjazdowa Sesja Naukowa Doktorantów Politechniki Łódzkiej (year: 2016, pages: 66), Publisher: Wydawnictwa Politechniki Łódzkiej
- Date:
- conference 11-13.04.2016 r, Łódź, Polska
- Status:
- Published
-
The application of Raman imaging in the analysis of biological systems
- Authors:
- M. Kopeć, B. Brożek-Płuska, J. Surmacki, H. Abramczyk
- Conference:
- EMLG/JMLG Annual Meeting 2016 (year: 2016, pages: brak), Publisher: EMLG/JMLG
- Date:
- conference 11-16.09.2016
- Status:
- Published
-
Obrazowanie Ramana w analizie układów biologicznych-skala mikro,
- Authors:
- Monika Kopeć, Beata Brożek-Płuska, Halina Abramczyk
- Conference:
- Mała Wielka Nauka, Innowacje idee przyszłości (year: 2015, pages: 81), Publisher: Wydział Chemiczny PŁ
- Date:
- conference 10-11.12
- Status:
- Published
-
Obrazowanie Ramana w biochemicznych i biomedycznych zastosowaniach na tle innych technik obrazowania,
- Authors:
- A. Korycińska, H. Abramczyk
- Conference:
- V Konferencja Biologii Molekularnej (year: 2016, pages: 46338), Publisher: Uniwersytet Łodzki
- Date:
- conference 7-9.04.2016r
- Status:
- Published
-
Obrazowanie Ramana ludzkiej tkanki nowotworowej oraz normalnych i nowotworowych kultur komórkowych,
- Authors:
- M. Kopeć, B. Brożek-Płuska, J. Surmacki, H. Abramczyk, A.K. Olejnik, A. Kaufman-Szymczyk, K. Fabianowska-Majewska
- Conference:
- IV Łódzkie Sympozjum Doktorantów Chemii (year: 2016, pages: 28), Publisher: Wydawnictwa Politechniki Łódzkiej
- Date:
- conference 12-13.05.2016 r
- Status:
- Published
-
Obrazowanie Ramana ludzkiej tkanki nowotworowej oraz nowotworowych i normalnych kultur komórkowych.
- Authors:
- Monika Kopeć, Jakub Surmacki, Halina Abramczyk
- Conference:
- II Łódzkie Sympozjum Doktorantów Chemii (year: 2014, pages: 100), Publisher: Dział Wydawnictw Naukowo-Dydaktycznych Politechniki Łódzkiej
- Date:
- conference 7-8.05
- Status:
- Published
- DOI:
- link to the publication
-
Confocal Raman microscpectroscopy of human tissues and human cell lines.
- Authors:
- B. Brożek-Płuska, J. Surmacki, M. Kopeć, J. Musiał, R. Kordek, I. Niedźwiecka, A. Morawiec-Sztandera, H. Abramczyk
- Conference:
- SPEC 2014, Shedding New Light on Disease (year: 2014, pages: 13), Publisher: Faculty of Chemistry, Jagiellonian University, Krakow, Poland
- Date:
- conference 17-22.08
- Status:
- Published
- DOI:
- link to the publication
-
Study of clofarabine induced effects in breast cancer cells MCF-7 by means of confocal Raman microspectroscopy.
- Authors:
- J. Surmacki, K. Lubecka-Pietruszewska, K. Fabianowska-Majewska, H. Abramczyk
- Conference:
- SPEC 2014, Shedding New Light on Disease (year: 2014, pages: P166), Publisher: Faculty of Chemistry, Jagiellonian University, Krakow, Poland
- Date:
- conference 17-22.08
- Status:
- Published
- DOI:
- link to the publication