Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The significance of blood platelet membrane fluidity in homocysteine-dependent modulation of acetylsalicylic acid antiplatelet effect - relevance to selected metabolic parameters

2012/07/N/NZ1/03140

Keywords:

acetylsalicylic acid homocysteine cell membrane fluidity phospholipases kainate receptor blood platelet

Descriptors:

  • NZ1_3: Biophysics

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Kamil Karolczak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 146 380 PLN

Project start date (Y-m-d): 2013-08-13

Project end date (Y-m-d): 2016-08-12

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Nie planowano zakupu aparatury..

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Aldosterone modulates blood homocysteine and cholesterol in coronary artery disease patients - a possible impact on atherothrombosis?
    Authors:
    K. Karolczak, P. Kubalczyk, R. Glowacki, R. Pietruszynski, C. Watala
    Academic press:
    Physiological Research (rok: 2018, tom: 67(2), strony: 197-207), Wydawca: Institute of Physiology, Czech Academy of Sciences
    Status:
    Published
    DOI:
    brak - link to the publication
  2. Inverse relationship between plasma glutathione concentration and fasting glycaemia in patients with coronary artery disease and concomitant type 2 diabetes – a pilot study
    Authors:
    K. Karolczak, P. Kubalczyk, R. Glowacki, R. Pietruszynski, C. Watala
    Academic press:
    Advances in Clinical and Experimental Medicine (rok: 2017, tom: 26(9), strony: 1359-1366), Wydawca: Wydawnictwo Uniwersytetu Medycznego we Wrocławiu
    Status:
    Published
    DOI:
    10.17219/acem/65441 - link to the publication
  3. Inhibition of glutamate receptors reduces the homocysteine-induced whole blood platelet aggregation but does not affect superoxide anion generation or platelet membrane fluidization
    Authors:
    K. Karolczak, A. Pieniazek, C. Watala
    Academic press:
    Platelets (rok: 2017, tom: 28(1), strony: 90-98), Wydawca: Taylor&Francis
    Status:
    Published
    DOI:
    10.1080/09537104.2016.1204438 - link to the publication
  1. Potential role of superoxide anion in homocysteine-induced fluidization of platelet membranes-evidence from preliminary EPR measurements
    Authors:
    K. Karolxzak, P. Danielska, A. Pieniazek
    Conference:
    IV Forum EMR_PL Poznan 27-29.VI.2016 (rok: 2016, ), Wydawca: Bruker
    Data:
    konferencja 27-29.06.
    Status:
    Published

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