The significance of blood platelet membrane fluidity in homocysteine-dependent modulation of acetylsalicylic acid antiplatelet effect - relevance to selected metabolic parameters

2012/07/N/NZ1/03140

Keywords

Descriptors

  • NZ1_3: Biofizyka

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Kamil Wojciech Karolczak

Number of co-investigators in the project: 2

Call

PRELUDIUM 4 – announced on 2012-09-15

Amount awarded
146 380 PLN
Project start date
2013-08-13
Project end date
2016-08-12
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Nie planowano zakupu aparatury..

Information in the final report

Publication in academic press/journals (3)

  1. Aldosterone modulates blood homocysteine and cholesterol in coronary artery disease patients - a possible impact on atherothrombosis?

    Authors:
    K. Karolczak, P. Kubalczyk, R. Glowacki, R. Pietruszynski, C. Watala
    Academic press:
    Physiological Research (year: 2018, volume: 67(2), pages: 197-207), Publisher: Institute of Physiology, Czech Academy of Sciences
    Status:
    Published
  2. Inverse relationship between plasma glutathione concentration and fasting glycaemia in patients with coronary artery disease and concomitant type 2 diabetes – a pilot study

    Authors:
    K. Karolczak, P. Kubalczyk, R. Glowacki, R. Pietruszynski, C. Watala
    Academic press:
    Advances in Clinical and Experimental Medicine (year: 2017, volume: 26(9), pages: 1359-1366), Publisher: Wydawnictwo Uniwersytetu Medycznego we Wrocławiu
    Status:
    Published
    DOI:
    10.17219/acem/65441 – link to the publication
  3. Inhibition of glutamate receptors reduces the homocysteine-induced whole blood platelet aggregation but does not affect superoxide anion generation or platelet membrane fluidization

    Authors:
    K. Karolczak, A. Pieniazek, C. Watala
    Academic press:
    Platelets (year: 2017, volume: 28(1), pages: 90-98), Publisher: Taylor&Francis
    Status:
    Published
    DOI:
    10.1080/09537104.2016.1204438 – link to the publication

Articles in post-conference publications (1)

  1. Potential role of superoxide anion in homocysteine-induced fluidization of platelet membranes-evidence from preliminary EPR measurements

    Authors:
    K. Karolxzak, P. Danielska, A. Pieniazek
    Conference:
    IV Forum EMR_PL Poznan 27-29.VI.2016 (year: 2016, pages: 60), Publisher: Bruker
    Date:
    conference 27-29.06.
    Status:
    Published

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