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Conjugated polymer matrices for controlled release of biologically active compounds - synthesis and characterization

2012/07/N/ST5/01878

Keywords

Descriptors

  • ST5_3: Modyfikacja powierzchni materiałów
  • ST5_12: Materiały "inteligentne" – materiały samoorganizujące się, materiały reagujące na bodźce zewnętrzne
  • ST5_11: Synteza biomateriałów

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Politechnika Śląska, Wydział Chemiczny

Voivodeship: śląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Katarzyna Zofia Krukiewicz

Number of co-investigators in the project: 3

Call

PRELUDIUM 4 – announced on 2012-09-15

Amount awarded
132 125 PLN
Project start date
2013-07-10
Project end date
2016-12-09
Project duration
41 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (8)

  1. Two approaches to the model drug immobilization into conjugated polymer matrix

    Authors:
    Katarzyna Krukiewicz, Anna Stokfisz, Jerzy K Zak
    Academic press:
    Materials Science and Engineering: C (year: 2015, volume: 54, pages: 176-181), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2015.05.017 – link to the publication

  2. Advancing the delivery of anticancer drugs: conjugated polymer / triterpenoid composite

    Authors:
    Katarzyna Krukiewicz, Tomasz Jarosz, Jerzy K. Zak, Mieczyslaw Lapkowski, Piotr Ruszkowski, Teresa Bobkiewicz-Kozlowska, Barbara Bednarczyk-Cwynar
    Academic press:
    Acta Biomaterialia (year: 2015, volume: 19, pages: 158-165), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.actbio.2015.03.006 – link to the publication

  3. Conjugated polymers as robust carriers for controlled delivery of anti-inflammatory drugs

    Authors:
    Katarzyna Krukiewicz, Jerzy K. Żak
    Academic press:
    Journal of Materials Science (year: 2014, volume: 49, pages: 5738-5745), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s10853-014-8292-2 – link to the publication

  4. EQCM verification of the concept of drug immobilization and release from conducting polymer matrix

    Authors:
    Katarzyna Krukiewicz; Barbara Bednarczyk-Cwynar; Jerzy K Zak
    Academic press:
    Electrochimica Acta (year: 2016, volume: 212, pages: 694-700), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.electacta.2016.07.055 – link to the publication

  5. The effect of solvent on the synthesis and physicochemical properties of poly(3,4-ethylenedioxypyrrole)

    Authors:
    Katarzyna Krukiewicz; Tomasz Jarosz; Artur P Herman; Roman Turczyn; Slawomir Boncel; Jerzy K Zak
    Academic press:
    Synthetic Metals (year: 2016, volume: 217, pages: 231-236), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.synthmet.2016.04.005 – link to the publication

  6. Biomaterial-based regional chemotherapy: local anticancer drug delivery to enhance chemotherapy and minimize its side-effects

    Authors:
    Katarzyna Krukiewicz, Jerzy K. Żak
    Academic press:
    Materials Science and Engineering C (year: 2016, volume: 62, pages: 927-942), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2016.01.063 – link to the publication

  7. An electrically controlled drug delivery system based on conducting poly(3,4-ethylenedioxypyrrole) matrix

    Authors:
    Katarzyna Krukiewicz, Patrycja Zawisza, Artur P. Herman, Roman Turczyn, Sławomir Boncel, Jerzy K. Zak
    Academic press:
    Bioelectrochemistry (year: 2016, volume: 108, pages: 13-20), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioelechem.2015.11.002 – link to the publication

  8. Betulin-loaded PEDOT films for regional chemotherapy

    Authors:
    Krukiewicz K., Cichy M., Ruszkowski P., Turczyn R., Jarosz T., Zak J.K., Lapkowski M., Bednarczyk-Cwynar B.
    Academic press:
    Materials Science and Engineering C (year: 2017, volume: 73, pages: 611-615), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2016.12.115 – link to the publication

Articles in post-conference publications (13)

  1. Physicochemical properties of poly(3,4-ethylenedioxypyrrole) – a novel conjugated polymer with biomedical implications

    Authors:
    Katarzyna Krukiewicz, Jerzy K. Żak
    Conference:
    Electrochemistry 2014 Basic Science and Key Technology for Future Applications (year: 2014, pages: 232), Publisher: Johannes Gutenberg Universitat Mainz
    Date:
    conference 22-24.09.2014
    Status:
    Published

  2. Conducting poly(3,4-ethylenedioxypyrrole) matrix for localized delivery of ibuprofen

    Authors:
    Katarzyna Krukiewicz, Patrycja Zawisza, Jerzy K. Żak
    Conference:
    12th International Congress of Young Chemists YoungChem2014 (year: 2014, pages: 46), Publisher: Chemical Scientific Society Flogiston, Warsaw University of Technology
    Date:
    conference 8-12.10.2014
    Status:
    Published

  3. Polimery przewodzące jako nośniki leków przeciwnowotworowych

    Authors:
    Katarzyna Krukiewicz, Tomasz Jarosz, Jerzy K. Żak, Piotr Ruszkowski, Teresa Bobkiewicz-Kozłowska, Barbara Bednarczyk-Cwynar
    Conference:
    Pomiędzy Naukami – zjazd fizyków i chemików (year: 2014, pages: 39), Publisher: HARIT Krzysztof Bednarek
    Date:
    conference 26.09.2014
    Status:
    Published

  4. Local Delivery of Biologically Active Compounds Based on Conjugated Polymer Matrices

    Authors:
    Katarzyna Krukiewicz, Tomasz Jarosz, Barbara Bednarczyk-Cwynar, Piotr Ruszkowski, Jerzy K. Zak
    Conference:
    66th Annual Meeting of the International Society of Electrochemistry (year: 2015, pages: S16-006), Publisher: ISE
    Date:
    conference 4-9.10.2015
    Status:
    Published

  5. Wykorzystanie polimerów skoniugowanych w systemach kontrolowanego uwalniania leków

    Authors:
    Krukiewicz K., Kurowska A., Radlik M., Jarosz T.
    Conference:
    IV Ogólnopolska Konferencja Naukowa Pomiędzy Naukami – zjazd fizyków i chemików (year: 2015, pages: 51), Publisher: UŚ
    Date:
    conference 18.09.2015
    Status:
    Published

  6. On-Demand Release of Dexamethasone from Conjugated Polymer Matrix

    Authors:
    Katarzyna Krukiewicz, Artur P. Herman, Sławomir Boncel, Jerzy K. Zak
    Conference:
    27th European Conference on Biomaterials (year: 2015, pages: 307), Publisher: ESB
    Date:
    conference 30.08.–3.09.2015
    Status:
    Published

  7. Cytotoxic surfaces for regional chemotherapy

    Authors:
    Krukiewicz K., Cichy M., Turczyn R., Jarosz T., Zak J.K., Bednarczyk-Cwynar B., Ruszkowski P.
    Conference:
    25th Conference on Biomaterials in Medicine and Veterinary Medicine (year: 2016, pages: 78), Publisher: Stowarzyszenie Biomateriałów i Wydział Inżynierii Materiałowej i Ceramiki Akademii Górniczo-Hutniczej im. St. Staszica w Krakowie
    Date:
    conference 12-15.10.2016
    Status:
    Published

  8. Poly(3,4-ethylenedioxypyrrole) – novel conducting polymer with biomedical applications

    Authors:
    Krukiewicz K., Gniazdowska B., Turczyn R., Jarosz T., Herman A.P., Boncel S., Zak J.K.
    Conference:
    25th Conference on Biomaterials in Medicine and Veterinary Medicine (year: 2016, pages: 79), Publisher: Stowarzyszenie Biomateriałów i Wydział Inżynierii Materiałowej i Ceramiki Akademii Górniczo-Hutniczej im. St. Staszica w Krakowie
    Date:
    conference 12-15.10.2016
    Status:
    Published

  9. Conducting polymer bio-interface for neuroregeneration: poly(3,4-ethylenedioxypyrrole)/ibuprofen system

    Authors:
    Krukiewicz K., Zawisza P., Herman A., Boncel S., Zak J.K.
    Conference:
    10th World Biomaterials Congress (year: 2016, pages: 1), Publisher: WSB
    Date:
    conference 17-22.05.2016
    Status:
    Published
    DOI:
    link to the publication

  10. Two approaches to the model drug immobilization into polypyrrole matrix for drug delivery systems based on conjugated polymers

    Authors:
    Katarzyna Krukiewicz, Anna Stokfisz, Jerzy K. Żak
    Conference:
    3rd European Young Engineers Conference (year: 2014, pages: 199-200), Publisher: Faculty of Chemical and Process Engineering, Warsaw University of Technology
    Date:
    conference 29-30.04.2014
    Status:
    Published

  11. Conducting polymer platform for anti-cancer drug delivery

    Authors:
    Katarzyna Krukiewicz, Tomasz Jarosz, Jerzy K. Żak, Mieczysław Łapkowski, Piotr Ruszkowski, Teresa Bobkiewicz-Kozłowska, Barbara Bednarczyk-Cwynar
    Conference:
    26th Annual Conference of the European Society for Biomaterials (year: 2014, pages: 542), Publisher: European Society for Biomaterials
    Date:
    conference 31.08.-3.09.2014
    Status:
    Published

  12. Electrically-Triggered Delivery System for Regional Chemotherapy

    Authors:
    Katarzyna Krukiewicz, Magdalena Cichy, Barbara Bednarczyk-Cwynar, Piotr Ruszkowski, Tomasz Jarosz, Mieczyslaw Lapkowski, Jerzy K. Zak
    Conference:
    27th European Conference on Biomaterials (year: 2015, pages: 430), Publisher: ESB
    Date:
    conference 30.08.–3.092015
    Status:
    Published

  13. Miejscowe uwalnianie związków biologicznie aktywnych z przewodzących matryc polimerowych

    Authors:
    Katarzyna Krukiewicz, Magdalena Cichy, Barbara Gniazdowska, Jerzy K. Żak
    Conference:
    III Łódzkie Sympozjum Doktorantów Chemii (year: 2015, pages: 38), Publisher: Wydział Chemii UŁ
    Date:
    conference 27-28.04.2015
    Status:
    Published

Book publications / chapters in book publications (2)

  1. Matryce polimerów skoniugowanych dla celów inżynierii biomedycznej

    Authors:
    Katarzyna Krukiewicz, Jerzy K. Żak
    Book:
    I Interdyscyplinarna Sesja Wyjazdowa Doktorantów Politechniki Śląskiej (year: 2014, volume: I, pages: 150-156), Publisher: Wydawnictwo Uczelnianej Rady Samorządu Doktorantów Politechniki Śląskiej
    Status:
    Published

  2. Electrochemistry role in production of nano-coatings

    Authors:
    Katarzyna Krukiewicz, Jerzy K. Żak
    Book:
    Comprehensive guide for nanocoatings technology, Vol 1: Deposition and Mechanism (year: 2015, volume: 1, pages: 289-309), Publisher: Nova Publishers
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski