Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Molecular mechanism of GDF-15 and SDF-1-induced angiogenesis - non-canonical role of Nrf2 transcription factor

2012/07/B/NZ3/02912

Keywords:

angiogenesis Nrf2 transcription factor SDF-1 GDF-15

Descriptors:

  • NZ1_1: Molecular biology
  • NZ3_7: Signal transduction
  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Grochot-Przęczek 

Number of co-investigators in the project: 5

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 329 680 PLN

Project start date (Y-m-d): 2013-07-18

Project end date (Y-m-d): 2016-07-17

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. Cellular and molecular mechanisms of inflammation-induced angiogenesis
    Authors:
    Agata Szade, Anna Grochot-Przeczek, Urszula Florczyk, Alicja Jozkowicz, Jozef Dulak
    Academic press:
    IUBMB Life (rok: 2015, tom: 67, strony: 145-59), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/iub.1358 - link to the publication
  2. Simvastatin treatment up-regulates HO-1 in patients with abdominal aortic aneurysm but independently of Nrf2
    Authors:
    Aleksandra Piechota-Polanczyk, Aleksandra Kopacz, Damian Kloska, Branislav Zagrapan, Christoph Neumayer, Anna Grochot-Przeczek, Ihor Huk, Christine Brostjan, Jozef Dulak, Alicja Jozkowicz
    Academic press:
    Oxidative medicine and cellular longevity (rok: 2018, tom: 2018, strony: -), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2018/2028936 - link to the publication
  3. Nrf2 sequesters Keap1 preventing podosome disassembly: a quintessential duet moonlights in endothelium
    Authors:
    Damian Kloska, Aleksandra Kopacz, Dominik Cysewski, Martin Aepfelbacher, Jozef Dulak, Alicja Jozwkowicz, Anna Grochot-Przeczek
    Academic press:
    Antioxidants & Redox Signaling , Wydawca: Mary Ann Liebert
    Status:
    Submitted
  1. Non-canonical role of Nrf2 transcription factor in GDF-15 and SDF-1-induced angiogenesis.
    Authors:
    Kloska D, Kopacz A, Augustyniak A, Dulak J, Jozkowicz A, Grochot-Przeczek A.
    Conference:
    Joint Meeting of the European- Society-for-Microcirculation and European-Vascular-Biology-Organisation (rok: 2015, ), Wydawca: Karger Publishers
    Data:
    konferencja 3-6.06.2015
    Status:
    Published
  2. GDF-15 and SDF-1 promote angiogenesis via Nrf2-dependent mechanism not related to its transcriptional activity
    Authors:
    Grochot-Przeczek, Anna; Kloska, Damian; Dulak, Jozef; Jozkowicz, Alicja
    Conference:
    NAVBO Vascular Biology Meeting 2014 (rok: 2014, ), Wydawca: Angiogenesis/Springer
    Data:
    konferencja 19-23 października 2014
    Status:
    Published