Projects funded by the NCN
One-pot synthesis of O-2-isocepham and N-2-isocepham derivatives bearing retroamide/thioretroamide or phosphono/thiophosphono function - potential B-lactam antibiotics and B-lactamase inhibitors
2012/07/N/NZ7/01775
Keywords:
O-2-isocepham N-2-isocepham beta-lactam-antibiotics beta-lactamase inhibitors bacterial infections
Descriptors:
- NZ7_14: Pharmacy, pharmacotherapy, pharmacology
- ST5_23:
- ST5_16:
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Politechnika Gdańska, Wydział Chemiczny
woj. pomorskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 4 - announced on 2012-09-15
Amount awarded: 75 000 PLN
Project start date (Y-m-d): 2013-09-02
Project end date (Y-m-d): 2015-03-01
Project duration:: 18 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Pompa próżniowa - membranowa (KNF) (6 432 PLN)
- Lampa UV (3 554 PLN)
Information in the final report
- Publication in academic press/journals (1)
- Manganese(III) Promoted Cyclization of N-alkenyl-N-(2-hydroxyethyl) amides to Iso-Oxacepham Potent β-Lactamase InhibitorsAuthors:Paweł Punda, Marta Schielmann, Slawomir MakowiecAcademic press:Letters in Organic Chemistry (rok: 2017, tom: Vol 14 Issue 5, strony: 337-346), Wydawca: Bentham ScienceStatus:Accepted for publicationDOI:10.2174/1570178614666170321123252 - link to the publication