Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of selected transition metal ions in the removal of reactive oxygen species by melanin

2012/07/D/ST4/02211

Keywords:

melanin transition metal ions reactive oxygen species antioxidant properties prooxidant properties

Descriptors:

  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST4_12: Photochemistry
  • ST5_16:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Andrzej Żądło 

Number of co-investigators in the project: 3

Call: SONATA 4 - announced on 2012-09-15

Amount awarded: 497 545 PLN

Project start date (Y-m-d): 2013-07-04

Project end date (Y-m-d): 2017-03-03

Project duration:: 44 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Analizator wilekości cząstek (193 644 PLN)
  2. Bank do przechowywania próbek w temperaturze ciekłego azotu.
  3. Kwarcowy zestaw do przepływu gazu (dewar i grzałka).
  4. Zasilacz awaryjny UPS ORVALDI INV12-0,5kW.

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (1)
  1. Aerobic photoreactivity of synthetic eumelanins and pheomelanins: generation of singlet oxygen and superoxide anion
    Authors:
    Grzegorz Szewczyk, Andrzej Zadlo, Michal Sarna, Shosuke Ito, Kazumasa Wakamatsu, Tadeusz Sarna
    Academic press:
    Pigment Cell & Melanoma Research (rok: 2016, tom: 29, strony: 669-678), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/pcmr.12514 - link to the publication
  2. Redox active transition metal ions make melanin susceptible to chemical degradation induced by organic peroxide
    Authors:
    Andrzej Zadlo, Anna Pilat, Michal Sarna, Anna Pawlak, Tadeusz Sarna
    Academic press:
    Cell Biochemistry and Biophysics (rok: 2017, tom: 75, strony: 319-333), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12013-017-0793-6 - link to the publication
  3. Photoaging of retinal pigment epithelial melanosomes: the effect of photobleaching on morphology and reactivity of the pigment granules
    Authors:
    Andrzej Zadlo, Grzegorz Szewczyk, Michal Sarna,, Anna Kozinska, Anna Pilat, Patrycja Kaczara and Tadeusz Sarna
    Academic press:
    Free Radical Biology & Medicine (rok: 2016, tom: 97, strony: 320-329), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2016.06.012 - link to the publication
  4. The role of hydrogen peroxide and singlet oxygen in photodegradation of melanin
    Authors:
    Andrzej Zadlo, Shosuke Ito, Michal Sarna, Kazumasa Wakamatsu, Krystian Mokrzynski, Tadeusz Sarna
    Academic press:
    Photochemical & Photobiological Sciences (rok: 2020, tom: 19, strony: 654-667), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c9pp00481e - link to the publication
  5. Application of transition metal ions in a study of photoinduced modifications of melanin
    Authors:
    Andrzej Żądło
    Academic press:
    Acta Biochimica Polonica (rok: 2019, tom: 66, strony: 237-241), Wydawca: Polish Biochemical Society and the Committee of Biochemistry and Biophysics Polish Academy of Sciences
    Status:
    Published
    DOI:
    10.18388/abp.2018_2802 - link to the publication
  6. Interaction of iron ions with melanin
    Authors:
    Andrzej Żądło, Tadeusz Sarna
    Academic press:
    Acta Biochimica Polonica (rok: 2019, tom: 66, strony: 459-462), Wydawca: Polish Biochemical Society and the Committee of Biochemistry and Biophysics Polish Academy of Sciences
    Status:
    Published
    DOI:
    10.18388/abp.2019_2889 - link to the publication
  7. The influence of iron on selected properties of synthetic pheomelanin
    Authors:
    Andrzej Zadlo, Krystian Mokrzynski, Shosuke Ito, Kazumasa Wakamatsu, Tadeusz Sarna
    Academic press:
    Cell Biochemistry and Biophysics (rok: 2020, tom: 78, strony: 181-189), Wydawca: Springer
    Status:
    Published
    DOI:
    brak - link to the publication
  1. The influence of selected transition metal ions on the ability of melanin to decompose hydrogen peroxide
    Authors:
    A. C. Zadlo, A. K. Pilat, M. W. Sarna, A. A. Broniec, T. J. Sarna
    Conference:
    XXII International Pigment Cell Conference (rok: 2014, ), Wydawca: Wiley-Blackwell
    Data:
    konferencja 4 - 7 września
    Status:
    Published
    DOI:
    link to the publication

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