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Information on the principal investigator and host institution

Information of the project and the call

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Studies on the mechanism regulating expression of hormone-dependent cytochromes P450 in the rat liver under conditions of the pituitary desensitization caused by gonadoliberin analogs

2012/07/N/NZ4/02569

Keywords:

cytochromes P450 transcription factors hormones gonadoliberin' analogs buserelin cetrorelix

Descriptors:

  • NZ4_6: Endocrinology
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_15: Toxicology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Śląski Uniwersytet Medyczny w Katowicach, Wydział Lekarski w Katowicach

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Rafał Skowronek 

Number of co-investigators in the project: 3

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 148 200 PLN

Project start date (Y-m-d): 2013-08-08

Project end date (Y-m-d): 2016-08-07

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. Expression of cytochrome P450 2C and 3A in female rat liver after long-term administration of gonadoliberin analogs
    Authors:
    Rafał Skowronek, Piotr Czekaj, Aleksandra Suszka-Świtek, Ewa Czech, Anna Wiaderkiewicz, Danuta Plewka, Aleksandra Bryzek
    Academic press:
    International Journal of Occupational Medicine and Environmental Health (rok: 2016, tom: 29(2), strony: 293–314), Wydawca: Nofer Institute of Occupational Medicine
    Status:
    Published
    DOI:
    10.13075/ijomeh.1896.00528 - link to the publication
  1. An experimental approach to the mechanism of growth hormone-dependent expression of drug-metabolizing cytochromes P450
    Authors:
    Rafał Skowronek, Aleksandra Suszka-Świtek, Piotr Czekaj
    Conference:
    XLVIII Sympozjum Polskiego Towarzystwa Histochemików i Cytochemików (rok: 2014, ), Wydawca: Polskie Towarzystwo Histochemików i Cytochemików
    Data:
    konferencja 3-6.09.2014
    Status:
    Published
  2. Changes in the concentration of sex hormones and growth hormone caused by long- and short-term administration of gonadoliberin analogs in female rats
    Authors:
    Rafał Skowronek, Aleksandra Suszka-Świtek, Kamil Sołtysik, Emanuel Kolanko, Piotr Czekaj
    Conference:
    49 Sympozjum Polskiego Towarzystwa Histochemików i Cytochemików "Współczesne techniki mikroskopowe i molekularne w biologii i medycynie" (rok: 2015, ), Wydawca: Polskie Towarzystwo Histochemików i Cytochemików
    Data:
    konferencja 9-12.09.2015
    Status:
    Published
  3. The studies on the mechanism of growth hormone-dependent cytochromes P450 expresion after long-term administration of GnRH agonist and antagonist
    Authors:
    Rafał Skowronek, Piotr Czekaj, Aleksandra Suszka-Świtek, Danuta Plewka, Ewa Czech, Anna Wiaderkiewicz, Aleksandra Bryzek
    Conference:
    The 11th International Symposium on GnRH: The HypothalamicPituitary-Gonadal Axis in Cancer and Reproduction (rok: 2014, ), Wydawca: Organizing Committee
    Data:
    konferencja 9-11.02.2014
    Status:
    Published

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