Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Age-dependent infertility in females: effect of maternal aging on calcium homeostasis in mammalian oocytes

2012/07/D/NZ5/04301

Keywords:

infertility oocyte calcium aging

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ3_4: Ageing
  • NZ3_13: Developmental biology in animals

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Warszawski, Wydział Biologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Ajduk 

Number of co-investigators in the project: 3

Call: SONATA 4 - announced on 2012-09-15

Amount awarded: 448 600 PLN

Project start date (Y-m-d): 2013-07-10

Project end date (Y-m-d): 2017-05-09

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Oprogramowanie MatLab.
  2. System do filmowania poklatkowego wewnątrz inkubatora.
  3. Wytrząsarka bakteryjna z inkubatorem (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (2)
  1. Dynamics of cytoplasm and cleavage divisions correlates with preimplantation embryo development
    Authors:
    Robert Milewski, Marcin Szpila, Anna Ajduk (AA is a corresponding author)
    Academic press:
    Reproduction (rok: 2018, tom: 155, strony: 45305), Wydawca: Bioscientifica
    Status:
    Published
    DOI:
    10.1530/REP-17-0230 - link to the publication
  2. Time-lapse imaging of cleavage divisions in embryo quality assessment
    Authors:
    Robert Milewski and Anna Ajduk (AA and RM equally participated in the paper)
    Academic press:
    Reproduction (rok: 2017, tom: 154, strony: R37-R53), Wydawca: Bioscientifica
    Status:
    Published
    DOI:
    10.1530/REP-17-0004 - link to the publication
  3. Polarity and cell division orientation in the cleavage embryo: from worm to human
    Authors:
    Anna Ajduk and Magdalena Zernicka-Goetz
    Academic press:
    Molecular Human Reproduction (rok: 2016, tom: 22, strony: 691-703), Wydawca: Oxford Journals
    Status:
    Published
    DOI:
    10.1093/molehr/gav068 - link to the publication
  4. Wpływ starzenia na przebieg oscylacji [Ca2+]i w zapłodnionych oocytach ssaków
    Authors:
    Katarzyna Czajkowska, Anna Ajduk
    Academic press:
    Postępy Nauk Medycznych (rok: 2016, tom: XXIX, strony: 45-51), Wydawca: Wydawnictwo Medyczne Borgis
    Status:
    Published
  1. Effect of maternal age on mammalian oocytes: the pattern of fertilization-induced Ca2+ oscillations and developmental potential
    Authors:
    Katarzyna Czajkowska and Anna Ajduk
    Conference:
    EMBO Workshop: Molecular mechanisms of ageing and regeneration: From pluripotency to senescence (rok: 2016, ), Wydawca: EMBO
    Data:
    konferencja 16-24 sierpnia
    Status:
    Published
  2. Impact ofmaternal aging on development and chracteristics of fertilization-induced Ca2+ oscillations and cytoplasmic movements in mammalian oocytes
    Authors:
    Katarzyna Czajkowska and Anna Ajduk
    Conference:
    EMBO/EMBL Symposium: Biological oscillators: Design, Mechanism, Function (rok: 2015, ), Wydawca: EMBO/EMBL
    Data:
    konferencja 12-14 November
    Status:
    Published