Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Glycomic analysis of intestinal epithelial cell differentiation. Modulatory role of microRNA.

2012/07/D/NZ1/00523

Keywords:

microRNA cell differentiation enterocytes N-glycosylation glycosphingolipids

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Nauk o Zdrowiu

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Paweł Link-Lenczowski 

Number of co-investigators in the project: 4

Call: SONATA 4 - announced on 2012-09-15

Amount awarded: 499 258 PLN

Project start date (Y-m-d): 2013-07-22

Project end date (Y-m-d): 2017-07-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Chromatograf HPLC z wysokoczułym detektorem fluorescencyjnym (155 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. A switch of N-glycosylation of proteome and secretome during differentiation of intestinal epithelial cells
    Authors:
    Paweł Link-Lenczowski, Martyna Jastrzębska, Katarzyna Chwalenia, Małgorzata Pierzchalska, Anna Leja-Szpak, Joanna Bonior, Piotr Pierzchalski, Jolanta Jaworek
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (rok: 2019, tom: 1866 (12), strony: 45305), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2019.118555 - link to the publication
  1. Alpha-mannosidases activity is necessary for proper brush border formation during differentiation of intestinal epithelial cells.
    Authors:
    Paweł Link-Lenczowski, Martyna Jastrzebska, Katarzyna Chwalenia, Piotr Pierzchalski, Jolanta Jaworek
    Conference:
    12th Jenner Glycobiology and Medicine Symposium "Translational Glycobiology From Bench to Bedside" (rok: 2017, ), Wydawca: The Royal Society of Medicine
    Data:
    konferencja 6-9 maja 2017, Dubrovnik
    Status:
    Published
  2. Cancer cell lines as model for studying glycosylation changes upon re-differentiation
    Authors:
    Paweł Link-Lenczowski, Martyna Jastrzębska, Katarzyna Chwalenia, Piotr Pierzchalski, Jolanta Jaworek
    Conference:
    BIO 2016 Congress (rok: 2016, ), Wydawca: Acta Biochimica Polonica, 2016, Vol. 63 Nr 2
    Data:
    konferencja 13-16 września 2016, Wrocław
    Status:
    Published
    DOI:
    link to the publication
  3. Glycomic changes during colon adenocarcinoma re-differentiation.
    Authors:
    Paweł Link-Lenczowski, Katarzyna Chwalenia, Martyna Jastrzębska, Piotr Pierzchalski, Jolanta Jaworek
    Conference:
    Glyco23, XXIII International Symposium on Glycoconjugates (rok: 2015, ), Wydawca: Glycoconjugate Jornal (2015) 32, Springer
    Data:
    konferencja 15-20 września 2015
    Status:
    Published
    DOI:
    link to the publication

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