Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Penicillin G acylase (EC 3.5.1.11) in the kinetic resolution of phosphorus analogues of alpha-amino acids

2012/07/N/ST5/00253

Keywords:

Penicillin G acylase kinetic resolution phosphorus analogues of alpha-amino acids immobilized penicillin G acylase immobilization

Descriptors:

  • ST5_16:
  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Śląska, Wydział Chemiczny

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Katarzyna Zielińska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 98 000 PLN

Project start date (Y-m-d): 2013-07-29

Project end date (Y-m-d): 2016-07-28

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Kolumny z wypełnieniem chiralnym oraz prekolumny do HPLC (14 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Batch and in-flow kinetic resolution of racemic 1-(Nacylamino) alkylphosphonic and 1-(N-acylamino)alkylphosphinic acids and their esters using immobilized penicillin G acylase
    Authors:
    Katarzyna Zielińska, Katarzyna Szymańska, Roman Mazurkiewicz, Andrzej Jarzębski
    Academic press:
    Tetrahedron: Asymmetry (rok: 2017, tom: 28, strony: 146-152), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tetasy.2016.11.007 - link to the publication
  2. Penicillin G acylase-mediated kinetic resolution of racemic 1-(N-acylamino)alkylphosphonic and 1-(N-acylamino)alkylphosphinic acids and their esters
    Authors:
    Katarzyna Zielińska, Roman Mazurkiewicz, Katarzyna Szymańska, Andrzej Jarzębski, Sylwia Magiera, Karol Erfurt
    Academic press:
    Journal of Molecular Catalysis B: Enzymatic (rok: 2016, tom: 132, strony: 31-40), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molcatb.2016.05.011 - link to the publication