Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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miR-34a as a potential negative modulator of bcl2 and cdk6 gene expression in fish exposed to microcystin-LR

2012/07/N/NZ1/03143

Keywords:

microcystin-LR microRNA mechanism of hepatotoxicity RNA interference bcl2 cdk6 Coregonus sp. (whitefish)

Descriptors:

  • NZ1_1: Molecular biology
  • NZ7_15: Toxicology
  • NZ7_2: Environment and health risks

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauk o Środowisku

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Alicja Łakomiak 

Number of co-investigators in the project: 3

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 98 800 PLN

Project start date (Y-m-d): 2013-08-01

Project end date (Y-m-d): 2015-07-31

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. miR-34a and bcl-2 expression in whitefish (Coregonus lavaretus) after microcystin-LR exposure
    Authors:
    Alicja Łakomiak, Paweł Brzuzan, Ewa Jakimiuk, Maciej Florczyk, Maciej Woźny
    Academic press:
    Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology (rok: 2016, tom: 193, strony: 47-56), Wydawca: Christopher Moyes
    Status:
    Published
    DOI:
    10.1016/j.cbpb.2015.12.005. - link to the publication
  2. Splice-acceptor site mutation in p53 gene of hu888 zebrafish line
    Authors:
    Alicja Piasecka, Paweł Brzuzan, Maciej Woźny, Sławomir Ciesielski, Dariusz Kaczmarczyk
    Academic press:
    Journal of Applied Genetics (rok: 2015, tom: 56, strony: 115-121), Wydawca: Marek Switonski
    Status:
    Published
    DOI:
    10.1007/s13353-014-0239-4 - link to the publication
  1. miR-34a jako negatywny modulator ekspresji genu bcl2 w odpowiedzi na działanie mikrocystyny-LR u ryb
    Authors:
    Alicja Piasecka, Paweł Brzuzan, Ewa Jakimiuk, Maciej Florczyk
    Conference:
    Człowiek, żywność, środowisko. Problemy współczesnej toksykologii (rok: 2014, ), Wydawca: Wydawnictwo UWM
    Data:
    konferencja 16-19.09.2014
    Status:
    Published