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Information on the principal investigator and host institution

Information of the project and the call

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Assessment of protective immunity against fasciolosis through vaccination of sheep with a multivalent stage-specific recombinant protein vaccine

2012/06/M/NZ6/00115

Keywords:

Fasciola multivalent vaccine mucosal immunity

Descriptors:

  • NZ6_6: Parasitology
  • NZ6_3: Animal immunology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Parazytologii im. Witolda Stefańskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Luke Norbury 

Number of co-investigators in the project: 8

Call: HARMONIA 3 - announced on 2012-06-15

Amount awarded: 306 000 PLN

Project start date (Y-m-d): 2013-04-29

Project end date (Y-m-d): 2016-07-28

Project duration:: 39 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  1. Vaccination against Fasciola hepatica using cathepsin L3 and B3 proteases delivered alone or in combination
    Authors:
    Wesołowska A, Basałaj K, Norbury L.J, Sielicka A, Wędrychowicz H, Zawistowska-Deniziak A
    Academic press:
    Veterinary Parasitology (rok: 2018, tom: 250, strony: 15-21), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.vetpar.2017.12.007 - link to the publication
  2. Sex and vaccination: Insights from female rats vaccinated with juvenile specific proteases from Fasciola hepatica
    Authors:
    Wesołowska A, Basałaj K, Norbury LJ, Sielicka A, Wędrychowicz H, Zawistowska-Deniziak A
    Academic press:
    Veterinary Parasitology (rok: 2018, tom: 255, strony: 91-96), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.vetpar.2018.04.001 - link to the publication
  3. Intranasal delivery of a formulation containing stage - specific recombinant proteins of Fasciola hepatica cathepsin L5 and cathepsin B2 triggers an anti-fecundity effect and an adjuvant - mediated reduction in fluke burden in sheep
    Authors:
    Luke J. Norbury, Katarzyna Basałaj, Anna Zawistowska-Deniziak, Alicja Sielicka, Przemysław Wilkowski, Agnieszka Wesołowska, Peter M. Smooker, Halina Wędrychowicz
    Academic press:
    Veterinary Parasitology (rok: 2018, tom: 258, strony: 14-23), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.vetpar.2018.05.008ne - link to the publication

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