Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of the transcription factor FOXN1 in skin wound healing.

2012/05/B/NZ5/01537

Keywords:

FOXN1 skin scar matrix metalloproteinases wound regeneration mouse

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_4: Pathogenesis of animal diseases
  • NZ5_9: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Rozrodu Zwierząt i Badań Żywności PAN

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Barbara Kozak 

Number of co-investigators in the project: 7

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 1 016 308 PLN

Project start date (Y-m-d): 2013-02-06

Project end date (Y-m-d): 2016-02-05

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Doposażenie zwierzętarni w klatki dla myszy (40szt) (40 szt.) (8 400 PLN)
  2. Doposażenie do mikroskopu OLYMPUS BX43 wyposażenia do fluorescencji z oprogramowaniem (66 000 PLN)
  3. Automatyczny licznik komorek (32 000 PLN)
  4. zbiornik do magazynowania w ciekłym azocie.
  5. 6. Zestaw do analizy metoda Western Blot (8 600 PLN)
  6. Sterylizator laboratoryjny (14 000 PLN)
  7. Zestaw do izolacji białek - Sonikator (Ultrasonic Processor) (20 000 PLN)
  8. laptop.

Information in the final report

  • Publication in academic press/journals (6)
  1. Foxn1 and Mmp-9 expression in intact skin and during excisional wound repair in young, adult and old C57Bl/6 mice
    Authors:
    Marta Kopcewicz, Anna Kur-Piotrowska, Joanna Bukowska, Jeffrey M. Gimble, Barbara Gawronska-Kozak
    Academic press:
    Wound Repair and Regeneration (rok: 2017, tom: 25(2), strony: 248-259), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/wrr.12524 - link to the publication
  2. Brown and brite adipocytes: Same function, but different origin and response
    Authors:
    Chu, Dinh-Toi; Gawronska-Kozak, Barbara
    Academic press:
    Biochimie (rok: 2017, tom: 138, strony: 102-105), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biochi.2017.04.017 - link to the publication
  3. Foxn1 Transcription Factor Regulates Wound Healing of Skin through Promoting Epithelial-Mesenchymal Transition
    Authors:
    Barbara Gawronska-Kozak , Anna Grabowska, Anna Kur-Piotrowska, Marta Kopcewicz
    Academic press:
    PLOS One (rok: 2016, tom: 11(3), strony: 45312), Wydawca: plos.org
    Status:
    Published
    DOI:
    10.1371/journal.pone.0150635 - link to the publication
  4. Animal models of skin regeneration
    Authors:
    Barbara Gawronska-Kozak , Anna Grabowska , Marta Kopcewicz , Anna Kur
    Academic press:
    Reproductive Biology (rok: 2014, tom: 14, strony: 61-67), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/B978-0-12-800280-3.00001-3 - link to the publication
  5. Preparation and Differentiation of Mesenchymal Stem Cells from Ears of Adult Mice
    Authors:
    Barbara Gawronska-Kozak
    Academic press:
    Methods in Enzymology (rok: 2014, tom: 538, strony: 45304), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/B978-0-12-800280-3.00001-3 - link to the publication
  6. Neotenic phenomenon in gene expression in the skin of Foxn1- deficient (nude) mice - a projection for regenerative skin wound healing.
    Authors:
    Anna Kur-Piotrowska, M. Kopcewicz, L.P. Kozak, P. Sachadyn, A. Grabowska, B. Gawronska-Kozak
    Academic press:
    BMC Genomics (rok: 2017, tom: 18(1), strony: 45306), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1186/s12864-016-3401-z - link to the publication

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