Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Polymeric biomaterials doped with peripherally modified porphyrazines of potential usage in photodynamic therapy

2012/05/N/NZ7/00624

Keywords:

porphyrazines polymeric membranes singlet oxygen photosensitizer photodynamic therapy cancers

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • ST4_17: Chemical reactions: mechanisms, thermodynamics, kinetics
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Jarosław Piskorz 

Number of co-investigators in the project: 3

Call: PRELUDIUM 3 - announced on 2012-03-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2013-02-01

Project end date (Y-m-d): 2016-07-31

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (6)
  1. Liposomal formulations of magnesium sulfanyl tribenzoporphyrazines for the photodynamic therapy of cancer
    Authors:
    J. Piskorz, D. T. Mlynarczyk, W. Szczolko, K. Konopka, N. Düzgüneş, J. Mielcarek
    Academic press:
    Journal of Inorganic Biochemistry , Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. Badania w dziedzinie azotowych analogów porfiryn i ich zastosowania w przemyśle barwników syntetycznych
    Authors:
    J. Piskorz, T. Goslinski, J. Mielcarek
    Academic press:
    Przemysł Chemiczny (rok: 2014, tom: 93, strony: 1855-1858), Wydawca: SIGMA-NOT
    Status:
    Published
    DOI:
    10.12916/przemchem.2014.1855 - link to the publication
  3. Sulfanyl porphyrazines: molecular barrel-like self-assembly in crystals, optical properties and in vitro photodynamic activity towards cancer cells
    Authors:
    J. Piskorz, S. Lijewski, M. Gierszewski, K. Gorniak, L. Sobotta, B. Wicher, E. Tykarska, N. Düzgüneş, K. Konopka, M. Sikorski, M. Gdaniec, J. Mielcarek, T. Goslinski
    Academic press:
    Dyes and Pigments (rok: 2017, tom: 136, strony: 898-908), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dyepig.2016.09.054 - link to the publication
  4. Diazepinoporphyrazines containing peripheral styryl substituents and their promising nanomolar photodynamic activity against oral cancer cells in liposomal formulations
    Authors:
    J. Piskorz, K. Konopka, N. Düzgüneş, Z. Gdaniec, J. Mielcarek, T. Goslinski
    Academic press:
    ChemMedChem (rok: 2014, tom: 9, strony: 1775-1782), Wydawca: WILEY-VCH
    Status:
    Published
    DOI:
    10.1002/cmdc.201402085 - link to the publication
  1. Novel porphyrazines possessing biphenylmethylsulfanyl substituents as potential photosensitizers for the photodynamic therapy
    Authors:
    Witkowska M., Porolnik W., Podciechowska K., Mielcarek J., Piskorz J.
    Conference:
    9th Polish-German Symposium on Pharmaceutical Sciences in Krakow (rok: 2017, ), Wydawca: Polish-German Symposium on Pharmaceutical Sciences
    Data:
    konferencja 26-27 V
    Status:
    Published
  2. Sulfur porphyrazines possessing 4-bromobenzyl and 4-phenylbenzyl peripheral substituents - synthesis and physico-chemical properties
    Authors:
    Lijewski S., Górniak K., Piskorz J., Sobotta Ł., Mielcarek J., Gośliński T
    Conference:
    VI Konwersatorium Chemii Medycznej (rok: 2014, ), Wydawca: VI Konwersatorium Chemii Medycznej
    Data:
    konferencja 18-20 IX
    Status:
    Published
  3. Synthesis and physical-chemical properties of novel porphyrazines possessing annulated styryldiazepine rings
    Authors:
    Piskorz J., Gośliński T., Mielcarek J
    Conference:
    VI Konwersatorium Chemii Medycznej (rok: 2014, ), Wydawca: VI Konwersatorium Chemii Medycznej
    Data:
    konferencja 18-20 IX
    Status:
    Published
  4. X-ray structural analysis of sulfanyl maleonitrile and porphyrazine derivatives
    Authors:
    Grajewski M., Lijewski S., Piskorz J., Wicher B., Tykarska E., Gdaniec M., Mielcarek J., Goslinski T
    Conference:
    VIII Konwersatorium Chemii Medycznej (rok: 2016, ), Wydawca: Polskie Towarzystwo Chemii Medycznej
    Data:
    konferencja 15-17 IX
    Status:
    Published
  5. Polymeric biomaterials doped with peripherally modified porphyrazines of potential usage in photodynamic therapy
    Authors:
    Piskorz J., Lijewski S., Düzgüneş N., Konopka K., Gośliński T., Mielcarek J.
    Conference:
    23rd Young Research Fellow Meeting (rok: 2016, ), Wydawca: Société de Chimie Thérapeutique
    Data:
    konferencja 15-17 II
    Status:
    Published
  6. Synthesis, photochemical and biological activity studies of sulfanyl porphyrazines possessing peripheral aromatic substituents
    Authors:
    Lijewski S., Piskorz J., Górniak K., Sobotta Ł., Düzgüneş N., Mielcarek J., Gośliński T.
    Conference:
    8th Polish-German Symposium on Pharmaceutical Science "Retrospects, insights and prospects" (rok: 2015, ), Wydawca: Kiel University
    Data:
    konferencja 29-30 V
    Status:
    Published
    DOI:
    link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy