Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Multifunctional nanocarriers for theranostics and their interactions with light

2012/05/B/ST4/00095

Keywords:

nanocapsules nanospheres quantum dots cytostatics two-photon absorption

Descriptors:

  • ST4_5: Analytical chemistry
  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • ST4_13: Solid-state chemistry, surface physicochemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Politechnika Wrocławska, Wydział Chemiczny

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Kazimiera Wilk 

Number of co-investigators in the project: 8

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 950 000 PLN

Project start date (Y-m-d): 2013-03-05

Project end date (Y-m-d): 2016-03-04

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Liofilizator Labconco FreeZone® 1l, teflon z pompą próżniową i komorą do suszenia (40 000 PLN)
  2. Moduł do obrazowania mikroskopowego metodą multiphoton fluorescence lifetime imaging (multiphoton FLIM) (190 000 PLN)
  3. Wysokociśnieniowy homogenizator mikrofluidyzacyjny (LV1) (4 660 PLN)
  4. bd - pozycja została dodana omyłkowo.

Information in the final report

  • Publication in academic press/journals (11)
  • Articles in post-conference publications (14)
  • Book publications / chapters in book publications (1)
  1. Biocompatible oil core nanocapsules as potential co-carriers of paclitaxel and fluorescent markers: preparation, characterization, and bioimaging
    Authors:
    Sławomir Drozdek, Urszula Bazylińska
    Academic press:
    Colloid and Polymer Science (rok: 2016, tom: 294, strony: 225–237), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00396-015-3767-5 - link to the publication
  2. Electroporation and lipid nanoparticles with cyanine IR-780 and flavonoids as efficient vectors to enhanced drug delivery in colon cancer
    Authors:
    Julita Kulbacka, Agata Pucek, Małgorzta Kotulska, Magda Dubińska-Magiera, Joanna Rossowska, Marie-P. Rols, Kazimiera A. Wilk
    Academic press:
    Bioelectrochemistry (rok: 2016, tom: 110, strony: 19–31), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioelechem.2016.02.013 - link to the publication
  3. Nanoemulsion-templated polylelectrolyte multifunctionalnanocapsules for DNA entrapment and bioimaging
    Authors:
    Urszula Bazylińska, Jolanta Saczko
    Academic press:
    Colloids and Surfaces B: Biointerfaces (rok: 2016, tom: 137, strony: 191–202), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2015.07.056 - link to the publication
  4. Co-encapsulating solid lipid nanoparticles for multifunctional therapeutics: Preparation and characterization
    Authors:
    Agata Pucek, Agnieszka Lewińska, Kazimiera A. Wilk
    Academic press:
    Colloids and Surfaces A: Physicochemical and Engineering Aspects (rok: 2016, tom: 510, strony: 45617), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfa.2016.08.032 - link to the publication
  5. Polymeric nanocapsules with up-converting nanocrystals cargo make ideal fluorescent bioprobes
    Authors:
    Urszula Bazylińska, Dominika Wawrzyńczyk, Julita Kulbacka, Renata Frąckowiak, Bartłomiej Cichy, Artur Bednarkiewicz, Marek Samoć, Kazimiera A. Wilk
    Academic press:
    Scientific Reports (rok: 2016, tom: 6, strony: 29746-29760), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/srep29746 - link to the publication
  6. New diamidequat-type surfactants in fabrication of long-sustained theranostic nanocapsules: Colloidal stability, drug delivery and bioimaging
    Authors:
    Urszula Bazylińska, Wojciech Zieliński, Julita Kulbacka, Marek Samoć, Kazimiera A. Wilk
    Academic press:
    Colloids and Surfaces B: Biointerfaces (rok: 2016, tom: 137, strony: 121-132), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2015.06.043 - link to the publication
  7. Two-photon induced fluorescence energy transfer in polymeric nanocapsules containing CdSexS1-x/ZnS core/shell quantum dots and zinc (II) phthalocyanine
    Authors:
    Sławomir Drozdek, Janusz Szeremeta, Łukasz Lamch, Marcin Nyk, Marek Samoć, Kazimiera A. Wilk
    Academic press:
    Journal of Physical Chemistry C (rok: 2016, tom: 120, strony: 15460-15470), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.jpcc.6b04301 - link to the publication
  8. Core/shell quantum dots encapsulated in biocompatible oil-core nanocarriers as two-photon fluorescent markers for bioimaging
    Authors:
    Urszula Bazylińska, Sławomir Drozdek, Marcin Nyk, Julita Kulbacka, Marek Samoc, Kazimiera A. Wilk
    Academic press:
    LANGMUIR (rok: 2014, tom: 30, strony: 14931-14943), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/la504558z - link to the publication
  9. Engineering of phosphatidylcholine – based solid lipid nanocarriers for flavonoids delivery
    Authors:
    Urszula Bazylińska, Agata Pucek, Michał Sowa, Ewa Matczak-Jon, Kazimiera A. Wilk
    Academic press:
    Colloids and Surfaces A: Physicochemical and Engineering Aspects (rok: 2014, tom: 460, strony: 483-493), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfa.2014.02.034 - link to the publication
  10. Two-Photon Absorption and Efficient Encapsulation of Near Infrared Emitting CdSexTe1-x Quantum Dots
    Authors:
    Janusz Szeremeta, Lukasz Lamch, Dominika Wawrzynczyk, Kazimiera A. Wilk, Marek Samoć, Marcin Nyk
    Academic press:
    Chemical Physics (rok: 2015, tom: 456, strony: 93-97), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chemphys.2014.12.007 - link to the publication
  11. FRET activated processes in smart nanotheranostics fabricated in a sustainable manner
    Authors:
    Dominika Wawrzyńczyk, Urszula Bazylińska, Łukasz Lamch, Julita Kulbacka, Anna Szewczyk, Artur Bednarkiewicz, Kazimiera A. Wilk, Marek Samoć
    Academic press:
    ChemSusChem (rok: 2018, ), Wydawca: Wiley
    Status:
    Accepted for publication
    DOI:
    10.1002/cssc.201801441 - link to the publication
  1. Biocompatible oil-core nanocapsules fabricated by emulsification solvent evaporation method as potential co-carriers of hydrophobic quantum dots CdSexS1-x/ZnS and zinc (II) phthalocyanine
    Authors:
    Sławomir Drozdek, Janusz Szeremeta, Marcin Nyk, Marek Samoć, Kazimiera A. Wilk
    Conference:
    1.1.X Szkoła Letnia dla Doktorantów (rok: 2015, ), Wydawca: bd.
    Data:
    konferencja 21.06 - 26.06.2015
    Status:
    Published
  2. Co-encapsulation of CdSe-ZnS quantum dots and phthalocyanine in nanocarriers for photodynamic therapy
    Authors:
    Janusz Szeremeta, Sławomir Drozdek, Marcin Nyk, Kazimiera A. Wilk, Marek Samoc
    Conference:
    The 4th International Conference on the Physics of Optical Materials and Devices (rok: 2015, ), Wydawca: bd.
    Data:
    konferencja 31.08 – 4.09.2015
    Status:
    Published
  3. Polylectrolyte oil-core nanocarriers of up-converting NaYF4:Tm3+,Yb3+ nanocrystals for enhanced delivery and bioimaging in human ovarian carcinoma (SKOV3) cells
    Authors:
    Urszula Bazylińska, Dominika Wawrzyńczyk, Ju;ita Kulbacka, Marek Samoć, Kazimiera A. Wilk,
    Conference:
    40th Congress of the Federation of the European Biochemical (FEBS) (rok: 2015, ), Wydawca: FEBS
    Data:
    konferencja 04-09.06.2015
    Status:
    Published
  4. Co-encapsulation of CdSexS1-x/ZnS quantum dots with photosensitizers - colloidal stability and optical properties
    Authors:
    Sławomir Drozdek, Janusz Szeremeta, Marcin Nyk, Marek Samoć, Kazimiera A. Wilk
    Conference:
    15th European Student Colloid Conference (rok: 2015, ), Wydawca: bd.
    Data:
    konferencja 8-11.06. 2015
    Status:
    Published
  5. Biocompatible theranostic oil-core nanocarriers as fluorescent markers for bioimaging and cancer therapy
    Authors:
    Urszula Bazylińska, Sławomir Drozdek, Marcin Nyk, Julita Kulbacka, Marek Samoć, Kazimiera A. Wilk
    Conference:
    29th Conference of The European Colloid and Interface Society (ECIS) (rok: 2015, ), Wydawca: ECIS
    Data:
    konferencja 06-11. 09. 2015
    Status:
    Published
  6. Encapsulation of up-converting NaYF4 nanocrystals in multifunctional polymeric nanocontainers
    Authors:
    Dominika Wawrzyńczyk, Urszula Bazylińska, Bartłomiej Cichy, Artur Bednarkiewicz, Marek Samoć, Kazimiera A. Wilk
    Conference:
    The 4th International Conference on the Physics of Optical Materials and Devices (rok: 2015, ), Wydawca: bd.
    Data:
    konferencja 31.08 – 4.09.2015
    Status:
    Published
  7. Facile co-encapsulation of hydrophobic quantum dots with photosensitizer in biocompatible nanocapsules
    Authors:
    Sławomir Drozdek, Janusz Szeremeta, Marcin Nyk, Marek Samoć, Kazimiera A. Wilk
    Conference:
    3rd European Congress of Applied Biotechnology (rok: 2015, ), Wydawca: bd.
    Data:
    konferencja 27.09-01.10.2015
    Status:
    Published
  8. Formulation, characterization and colloid stability of nanostructured lipid carriers for delivery of myricetin and bioimaging markers
    Authors:
    Agata Pucek, Julita Kulbacka, Agnieszka Lewińska, Kazimiera A. Wilk
    Conference:
    29th Conference of The European Colloid and Interface Society (ECIS) (rok: 2015, ), Wydawca: ECIS
    Data:
    konferencja 06-11. 09. 2015
    Status:
    Published
  9. Solid lipid nanoparticles as carriers for therapeutic and diagnostic substances
    Authors:
    Agata Pucek, Kazimiera A. Wilk
    Conference:
    X Szkoła Letnia dla Doktorantów, (rok: 2015, ), Wydawca: bd.
    Data:
    konferencja 21.06 - 26.06.2015
    Status:
    Published
  10. Exciting Nanoparticles and Nanocontainers with Nanoparticle Cargo by Nonlinear Absorption
    Authors:
    Marek Samoć, Kazimiera A. Wilk, Urszula Bazylińska, Marcin Nyk, Janusz Szeremeta, Sławomir Drozdek , Łukasz Lamch, Dominika Wawrzyńczyk
    Conference:
    ICNP 2015The 8th International Conference on Nanophotonics (rok: 2015, ), Wydawca: bd.
    Data:
    konferencja 24-28.05.2015
    Status:
    Published
  11. Nanoemulsion-templated polylelectrolyte multifunctional nanocapsules for DNA entrapment and bioimaging
    Authors:
    Urszula Bazylińska, Marek Kramarzewski, Jolanta Saczko
    Conference:
    28th Conference of the European Colloid and Interface Society (ECIS 2014) (rok: 2014, ), Wydawca: ECIS
    Data:
    konferencja 07-12.09.
    Status:
    Published
  12. New diamidequat-type surfactants in fabrication of long-sustained theranostic nanocapsules: colloidal stability and bioimaging
    Authors:
    Urszula Bazylińska, Wojciech Zieliński, Krzysztof Ciszewski, Marek Samoć, Kazimiera A. Wilk
    Conference:
    28th Conference of the European Colloid and Interface Society (ECIS 2014) (rok: 2014, ), Wydawca: ECIS
    Data:
    konferencja 07-12.09
    Status:
    Published
  13. Engineering of phosphatidylcholine – based solid lipid nanocarriers for flavonoid cocrystals delivery
    Authors:
    Kazimiera A. Wilk, Urszula Bazylińska, Michał Sowa, Ewa Matczak-Jon
    Conference:
    27th Conference of European Colloid and Interface Society (rok: 2013, ), Wydawca: -
    Data:
    konferencja 01-06.09.2013
    Status:
    Published
  14. Synteza i właściwości nanonośników wielofunkcyjnych
    Authors:
    Sławomir Drozdek
    Conference:
    XI Ogólnopolskie Seminarium Doktorantów "Na pograniczu Chemii i Biologii" (rok: 2013, ), Wydawca: -
    Data:
    konferencja 01-04.06.2013
    Status:
    Published
  1. "Od samoorganizacji molekularnej do doskonalszych farmaceutyków"
    Authors:
    Kazimiera A. Wilk
    Book:
    "W poszukiwaniu jedności - dwudziestolecie Studium Generale" pod redakcją Ewy Dobierzewskiej -Mozrzymas i Adama Jezierskiego . (rok: 2014, tom: XVIII, strony: 83-93), Wydawca: Wydawnictwo Uniwersytetu Wrocławskiego
    Status:
    Published

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