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Multifunctional nanocarriers for theranostics and their interactions with light

2012/05/B/ST4/00095

Keywords

Descriptors

  • ST4_5: Chemia i fizykochemia powierzchni
  • ST5_10: Nanomateriały: nanocząstki, nanorurki
  • ST4_13: Chemia fizyczna układów biologicznych

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Politechnika Wrocławska, Wydział Chemiczny

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Kazimiera Anna Wilk

Number of co-investigators in the project: 8

Call

OPUS 3 – announced on 2012-03-15

Amount awarded
950 000 PLN
Project start date
2013-03-05
Project end date
2016-03-04
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Liofilizator Labconco FreeZone® 1l, teflon z pompą próżniową i komorą do suszenia. Cost: 40 000 PLN
  2. Moduł do obrazowania mikroskopowego metodą multiphoton fluorescence lifetime imaging (multiphoton FLIM). Cost: 190 000 PLN
  3. Wysokociśnieniowy homogenizator mikrofluidyzacyjny (LV1). Cost: 4 660 PLN
  4. bd - pozycja została dodana omyłkowo.

Information in the final report

Publication in academic press/journals (11)

  1. Engineering of phosphatidylcholine – based solid lipid nanocarriers for flavonoids delivery

    Authors:
    Urszula Bazylińska, Agata Pucek, Michał Sowa, Ewa Matczak-Jon, Kazimiera A. Wilk
    Academic press:
    Colloids and Surfaces A: Physicochemical and Engineering Aspects (year: 2014, volume: 460, pages: 483-493), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfa.2014.02.034 – link to the publication

  2. Co-encapsulating solid lipid nanoparticles for multifunctional therapeutics: Preparation and characterization

    Authors:
    Agata Pucek, Agnieszka Lewińska, Kazimiera A. Wilk
    Academic press:
    Colloids and Surfaces A: Physicochemical and Engineering Aspects (year: 2016, volume: 510, pages: 46347), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfa.2016.08.032 – link to the publication

  3. New diamidequat-type surfactants in fabrication of long-sustained theranostic nanocapsules: Colloidal stability, drug delivery and bioimaging

    Authors:
    Urszula Bazylińska, Wojciech Zieliński, Julita Kulbacka, Marek Samoć, Kazimiera A. Wilk
    Academic press:
    Colloids and Surfaces B: Biointerfaces (year: 2016, volume: 137, pages: 121-132), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2015.06.043 – link to the publication

  4. Nanoemulsion-templated polylelectrolyte multifunctionalnanocapsules for DNA entrapment and bioimaging

    Authors:
    Urszula Bazylińska, Jolanta Saczko
    Academic press:
    Colloids and Surfaces B: Biointerfaces (year: 2016, volume: 137, pages: 191–202), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2015.07.056 – link to the publication

  5. Core/shell quantum dots encapsulated in biocompatible oil-core nanocarriers as two-photon fluorescent markers for bioimaging

    Authors:
    Urszula Bazylińska, Sławomir Drozdek, Marcin Nyk, Julita Kulbacka, Marek Samoc, Kazimiera A. Wilk
    Academic press:
    LANGMUIR (year: 2014, volume: 30, pages: 14931-14943), Publisher: ACS
    Status:
    Published
    DOI:
    10.1021/la504558z – link to the publication

  6. Two-Photon Absorption and Efficient Encapsulation of Near Infrared Emitting CdSexTe1-x Quantum Dots

    Authors:
    Janusz Szeremeta, Lukasz Lamch, Dominika Wawrzynczyk, Kazimiera A. Wilk, Marek Samoć, Marcin Nyk
    Academic press:
    Chemical Physics (year: 2015, volume: 456, pages: 93-97), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chemphys.2014.12.007 – link to the publication

  7. Two-photon induced fluorescence energy transfer in polymeric nanocapsules containing CdSexS1-x/ZnS core/shell quantum dots and zinc (II) phthalocyanine

    Authors:
    Sławomir Drozdek, Janusz Szeremeta, Łukasz Lamch, Marcin Nyk, Marek Samoć, Kazimiera A. Wilk
    Academic press:
    Journal of Physical Chemistry C (year: 2016, volume: 120, pages: 15460-15470), Publisher: ACS
    Status:
    Published
    DOI:
    10.1021/acs.jpcc.6b04301 – link to the publication

  8. Polymeric nanocapsules with up-converting nanocrystals cargo make ideal fluorescent bioprobes

    Authors:
    Urszula Bazylińska, Dominika Wawrzyńczyk, Julita Kulbacka, Renata Frąckowiak, Bartłomiej Cichy, Artur Bednarkiewicz, Marek Samoć, Kazimiera A. Wilk
    Academic press:
    Scientific Reports (year: 2016, volume: 6, pages: 29746-29760), Publisher: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/srep29746 – link to the publication

  9. Electroporation and lipid nanoparticles with cyanine IR-780 and flavonoids as efficient vectors to enhanced drug delivery in colon cancer

    Authors:
    Julita Kulbacka, Agata Pucek, Małgorzta Kotulska, Magda Dubińska-Magiera, Joanna Rossowska, Marie-P. Rols, Kazimiera A. Wilk
    Academic press:
    Bioelectrochemistry (year: 2016, volume: 110, pages: 19–31), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioelechem.2016.02.013 – link to the publication

  10. Biocompatible oil core nanocapsules as potential co-carriers of paclitaxel and fluorescent markers: preparation, characterization, and bioimaging

    Authors:
    Sławomir Drozdek, Urszula Bazylińska
    Academic press:
    Colloid and Polymer Science (year: 2016, volume: 294, pages: 225–237), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00396-015-3767-5 – link to the publication

  11. FRET activated processes in smart nanotheranostics fabricated in a sustainable manner

    Authors:
    Dominika Wawrzyńczyk, Urszula Bazylińska, Łukasz Lamch, Julita Kulbacka, Anna Szewczyk, Artur Bednarkiewicz, Kazimiera A. Wilk, Marek Samoć
    Status:
    Accepted for publication

Articles in post-conference publications (14)

  1. Polylectrolyte oil-core nanocarriers of up-converting NaYF4:Tm3+,Yb3+ nanocrystals for enhanced delivery and bioimaging in human ovarian carcinoma (SKOV3) cells

    Authors:
    Urszula Bazylińska, Dominika Wawrzyńczyk, Ju;ita Kulbacka, Marek Samoć, Kazimiera A. Wilk,
    Conference:
    40th Congress of the Federation of the European Biochemical (FEBS) (year: 2015, pages: bd.), Publisher: FEBS
    Date:
    conference 04-09.06.2015
    Status:
    Published

  2. Co-encapsulation of CdSe-ZnS quantum dots and phthalocyanine in nanocarriers for photodynamic therapy

    Authors:
    Janusz Szeremeta, Sławomir Drozdek, Marcin Nyk, Kazimiera A. Wilk, Marek Samoc
    Conference:
    The 4th International Conference on the Physics of Optical Materials and Devices (year: 2015, pages: bd.), Publisher: bd.
    Date:
    conference 31.08 – 4.09.2015
    Status:
    Published

  3. Biocompatible theranostic oil-core nanocarriers as fluorescent markers for bioimaging and cancer therapy

    Authors:
    Urszula Bazylińska, Sławomir Drozdek, Marcin Nyk, Julita Kulbacka, Marek Samoć, Kazimiera A. Wilk
    Conference:
    29th Conference of The European Colloid and Interface Society (ECIS) (year: 2015, pages: bd.), Publisher: ECIS
    Date:
    conference 06-11. 09. 2015
    Status:
    Published

  4. Co-encapsulation of CdSexS1-x/ZnS quantum dots with photosensitizers - colloidal stability and optical properties

    Authors:
    Sławomir Drozdek, Janusz Szeremeta, Marcin Nyk, Marek Samoć, Kazimiera A. Wilk
    Conference:
    15th European Student Colloid Conference (year: 2015, pages: bd.), Publisher: bd.
    Date:
    conference 8-11.06. 2015
    Status:
    Published

  5. Facile co-encapsulation of hydrophobic quantum dots with photosensitizer in biocompatible nanocapsules

    Authors:
    Sławomir Drozdek, Janusz Szeremeta, Marcin Nyk, Marek Samoć, Kazimiera A. Wilk
    Conference:
    3rd European Congress of Applied Biotechnology (year: 2015, pages: bd.), Publisher: bd.
    Date:
    conference 27.09-01.10.2015
    Status:
    Published

  6. Solid lipid nanoparticles as carriers for therapeutic and diagnostic substances

    Authors:
    Agata Pucek, Kazimiera A. Wilk
    Conference:
    X Szkoła Letnia dla Doktorantów, (year: 2015, pages: bd.), Publisher: bd.
    Date:
    conference 21.06 - 26.06.2015
    Status:
    Published

  7. Formulation, characterization and colloid stability of nanostructured lipid carriers for delivery of myricetin and bioimaging markers

    Authors:
    Agata Pucek, Julita Kulbacka, Agnieszka Lewińska, Kazimiera A. Wilk
    Conference:
    29th Conference of The European Colloid and Interface Society (ECIS) (year: 2015, pages: bd.), Publisher: ECIS
    Date:
    conference 06-11. 09. 2015
    Status:
    Published

  8. Exciting Nanoparticles and Nanocontainers with Nanoparticle Cargo by Nonlinear Absorption

    Authors:
    Marek Samoć, Kazimiera A. Wilk, Urszula Bazylińska, Marcin Nyk, Janusz Szeremeta, Sławomir Drozdek , Łukasz Lamch, Dominika Wawrzyńczyk
    Conference:
    ICNP 2015The 8th International Conference on Nanophotonics (year: 2015, pages: bd.), Publisher: bd.
    Date:
    conference 24-28.05.2015
    Status:
    Published

  9. Nanoemulsion-templated polylelectrolyte multifunctional nanocapsules for DNA entrapment and bioimaging

    Authors:
    Urszula Bazylińska, Marek Kramarzewski, Jolanta Saczko
    Conference:
    28th Conference of the European Colloid and Interface Society (ECIS 2014) (year: 2014, pages: Materiały elektroniczne, bez stron), Publisher: ECIS
    Date:
    conference 07-12.09.
    Status:
    Published

  10. Encapsulation of up-converting NaYF4 nanocrystals in multifunctional polymeric nanocontainers

    Authors:
    Dominika Wawrzyńczyk, Urszula Bazylińska, Bartłomiej Cichy, Artur Bednarkiewicz, Marek Samoć, Kazimiera A. Wilk
    Conference:
    The 4th International Conference on the Physics of Optical Materials and Devices (year: 2015, pages: bd.), Publisher: bd.
    Date:
    conference 31.08 – 4.09.2015
    Status:
    Published

  11. Biocompatible oil-core nanocapsules fabricated by emulsification solvent evaporation method as potential co-carriers of hydrophobic quantum dots CdSexS1-x/ZnS and zinc (II) phthalocyanine

    Authors:
    Sławomir Drozdek, Janusz Szeremeta, Marcin Nyk, Marek Samoć, Kazimiera A. Wilk
    Conference:
    1.1.X Szkoła Letnia dla Doktorantów (year: 2015, pages: bd.), Publisher: bd.
    Date:
    conference 21.06 - 26.06.2015
    Status:
    Published

  12. Synteza i właściwości nanonośników wielofunkcyjnych

    Authors:
    Sławomir Drozdek
    Conference:
    XI Ogólnopolskie Seminarium Doktorantów Na pograniczu Chemii i Biologii (year: 2013, pages: materiały elektroniczne bez stron), Publisher: -
    Date:
    conference 01-04.06.2013
    Status:
    Published

  13. New diamidequat-type surfactants in fabrication of long-sustained theranostic nanocapsules: colloidal stability and bioimaging

    Authors:
    Urszula Bazylińska, Wojciech Zieliński, Krzysztof Ciszewski, Marek Samoć, Kazimiera A. Wilk
    Conference:
    28th Conference of the European Colloid and Interface Society (ECIS 2014) (year: 2014, pages: materiały elektroniczne, bez stron), Publisher: ECIS
    Date:
    conference 07-12.09
    Status:
    Published

  14. Engineering of phosphatidylcholine – based solid lipid nanocarriers for flavonoid cocrystals delivery

    Authors:
    Kazimiera A. Wilk, Urszula Bazylińska, Michał Sowa, Ewa Matczak-Jon
    Conference:
    27th Conference of European Colloid and Interface Society (year: 2013, pages: materiały elektroniczne bez stron), Publisher: -
    Date:
    conference 01-06.09.2013
    Status:
    Published

Book publications / chapters in book publications (1)

  1. Od samoorganizacji molekularnej do doskonalszych farmaceutyków

    Authors:
    Kazimiera A. Wilk
    Book:
    W poszukiwaniu jedności - dwudziestolecie Studium Generale pod redakcją Ewy Dobierzewskiej -Mozrzymas i Adama Jezierskiego . (year: 2014, volume: XVIII, pages: 83-93), Publisher: Wydawnictwo Uniwersytetu Wrocławskiego
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski