Human obesity: the potential role of genes encoding sirtuins and epigenetic control of their activity.
2012/05/B/NZ5/01536
Keywords
Descriptors
- NZ5_1: Etiologia chorób człowieka
- NZ5_3: Patogeneza chorób człowieka
- NZ5_7: Leczenie chorób człowieka
Panel
NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution
Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 6
Call
OPUS 3 – announced on 2012-03-15
- Amount awarded
- 357 200 PLN
- Project start date
- 2013-02-20
- Project end date
- 2016-08-19
- Project duration
- 42 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Mikrowirówka z rotorem do wirowania max. 18 probówek typu Eppendorf od 0,2 do 2,0 ml. Cost: 8 500 PLN
- Zestaw 6 pipet badawczych (Eppendorf Reference i Eppendorf Research) i pipeta elektroniczna 0,5-10µl (Eppendorf Xplorer). Cost: 12 000 PLN
Information in the final report
Publication in academic press/journals (4)
-
In Search of New Therapeutic Targets in Obesity Treatment: Sirtuins.
- Authors:
- Kuryłowicz A
- Academic press:
- International Journal of Molecular Sciences (year: 2016, volume: 17 (4), pages: pii: E572), Publisher: MDPI Open Access Journals
- Status:
- Published
- DOI:
- 10.3390/ijms17040572 – link to the publication
-
SIRT1 and SIRT7 expression in adipose tissues of obese and normal-weight individuals is regulated by microRNAs but not by methylation status.
- Authors:
- Kurylowicz A, Owczarz M, Polosak J, Jonas MI, Lisik W, Jonas M, Chmura A, Puzianowska-Kuznicka M.
- Academic press:
- International Journal of Obesity (London). (year: 2016, volume: 40 (11), pages: 1635-1642), Publisher: Nature
- Status:
- Published
- DOI:
- link to the publication
-
Adiponectin/resistin interplay in serum and in adipose tissue of obese and normal-weight individuals
- Authors:
- •Jonas MI, Kurylowicz A, Bartoszewicz Z, Lisik W, Jonas M, Domienik-Karlowicz J, Puzianowska-Kuznicka M
- Academic press:
- Diabetology and Metabolic Syndrome (year: 2017, volume: 0,440972222222222, pages: 0,440972222222222), Publisher: BMC
- Status:
- Published
- DOI:
- 10.1186/s13098-017-0293-2 – link to the publication
-
NGS Reveals Molecular Pathways Affected by Obesity and Weight Loss-Related Changes in miRNA Levels in Adipose Tissue
- Authors:
- •Kuryłowicz A, Wicik Z, Owczarz M, Jonas MI, Kotlarek M, Świerniak M, Lisik W, Jonas M, Noszczyk B, Puzianowska-Kuźnicka M.
- Academic press:
- International Journal of Molecular Sciences (year: 2017, volume: 19 (1), pages: pii: E66), Publisher: MDPI Open Access Journals
- Status:
- Published
- DOI:
- 10.3390/ijms19010066 – link to the publication
Articles in post-conference publications (1)
-
Interferencja miRNA, a nie metylacja promotorów, ma wpływ na ekspresję genów SIRT1 i SIRT7 w tkankach tłuszczowych osób otyłych i o prawidłowej masie ciała.
- Authors:
- Kurylowicz A, Pietrzykowska M, Owczarz M, Polosak J, Jonas MI, Lisik W, Jonas M, Chmura A, Puzianowska-Kuznicka M
- Conference:
- XXI Zjazd Polskiego Towarzystwa Endokrynologicznego (year: 2016, pages: A46), Publisher: Via medica
- Date:
- conference 15-17.09.2016r
- Status:
- Published