Application of the Langmuir Monolayer Technique for the Investigation of the Interactions between Biiologically Active Pentacycliic Triterpenes and Structural Liipids of Bacterial and Mitochondriial Membranes

2012/05/B/ST5/00287

Keywords

Descriptors

  • ST5_4: Cienkie warstwy
  • ST5_16: Chemia biologiczna

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Uniwersytet Jagielloński, Wydział Chemii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Marcin Broniatowski

Number of co-investigators in the project: 3

Call

OPUS 3 – announced on 2012-03-15

Amount awarded
406 960 PLN
Project start date
2013-02-04
Project end date
2015-02-03
Project duration
24 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Lodówka.
  2. Obudowa wagi Langmuira.
  3. Pehametr.
  4. Waga powierzchniowa Langmuira przeznaczona do prowadzenia reakcji chemicznych na granicy faz woda powietrze, wraz z niezbędnymi akcesoriami. Cost: 200 000 PLN
  5. Zestaw do produkcji wody ultraczystej.

Information in the final report

Publication in academic press/journals (6)

  1. Antagonistic effects of alpha-tocopherol and ursolic acid on model bacterial membranes

    Authors:
    Marcin Broniatowski, Michał Flasiński, Katarzyna Hąc-Wydro
    Academic press:
    Biochimmica et Biophysica Acta Biomembranes (year: 2015, volume: 1848, pages: 2154-2162), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2015.05.009 – link to the publication
  2. Interactions of pentacyclic triterpene acids with cardiolipins and related phosphatidylglycerols in model systems

    Authors:
    Marcin Broniatowski, Michał Flasiński, Katarzyna Zięba, Paweł Miśkowiec
    Academic press:
    Biochimica et Biophysica Acta, Biomembranes (year: 2014, volume: 1838, pages: 2530-2538), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2014.05.027 – link to the publication
  3. Langmuir monolayer studies of the interaction of monoamphiphilic pentacyclic triterpenes with anionic mitochondrial and bacterial membrane phospholipids - Searching for the most active terpene

    Authors:
    Marcin Broniatowski, Michał Flasiński, Katarzyna Zięba, Paweł Miśkowiec
    Academic press:
    Biochimica et Biophysica Acta, Biomembranes (year: 2014, volume: 1838, pages: 2460-2472), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2014.05.009 – link to the publication
  4. Incorporation of pentacyclic triterpenes into mitochondrial membrane - Studies on the interaction in model 2D lipid systems

    Authors:
    Michał Flasiński, Katarzyna Hąc-Wydro, Marcin Broniatowski
    Academic press:
    Journal of Physical Chemistry B (year: 2014, volume: 118, pages: 12927-12937), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/jp508743j – link to the publication
  5. Grazing incidence diffraction studies of the interaction between ursane-type antimicrobial triterpenes and bacterial anionic phospholipids

    Authors:
    Marcin Broniatowski, Michał Flasiński, Paweł Wydro, Philippe Fontaine
    Academic press:
    Colloids and Surfaces B, Biointerfaces (year: 2015, volume: 128, pages: 561-567), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2015.03.009 – link to the publication
  6. Studies of the interactions of ursane-type bioactive terpenes with the model of Escherichia coli inner membrane - Langmuir monolayer approach

    Authors:
    Marcin Broniatowski, Patrycja Mastalerz, Michał Flasiński
    Academic press:
    Biochimica et Biophysica Acta, Biomembranes (year: 2015, volume: 1848, pages: 469-476), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2014.10.024 – link to the publication

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Graphic design and implementation: Jakub Piotrowski