Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Application of the Langmuir Monolayer Technique for the Investigation of the Interactions between Biiologically Active Pentacycliic Triterpenes and Structural Liipids of Bacterial and Mitochondriial Membranes

2012/05/B/ST5/00287

Keywords:

pentacycliic triiterpenes Langmuir monolayers model biomembranes

Descriptors:

  • ST5_4: Thin films
  • ST5_16:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Marcin Broniatowski 

Number of co-investigators in the project: 3

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 406 960 PLN

Project start date (Y-m-d): 2013-02-04

Project end date (Y-m-d): 2015-02-03

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Obudowa wagi Langmuira.
  2. Pehametr.
  3. Lodówka.
  4. Waga powierzchniowa Langmuira przeznaczona do prowadzenia reakcji chemicznych na granicy faz woda powietrze, wraz z niezbędnymi akcesoriami (200 000 PLN)
  5. Zestaw do produkcji wody ultraczystej.

Information in the final report

  • Publication in academic press/journals (6)
  1. Interactions of pentacyclic triterpene acids with cardiolipins and related phosphatidylglycerols in model systems
    Authors:
    Marcin Broniatowski, Michał Flasiński, Katarzyna Zięba, Paweł Miśkowiec
    Academic press:
    Biochimica et Biophysica Acta, Biomembranes (rok: 2014, tom: 1838, strony: 2530-2538), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2014.05.027 - link to the publication
  2. Studies of the interactions of ursane-type bioactive terpenes with the model of Escherichia coli inner membrane - Langmuir monolayer approach
    Authors:
    Marcin Broniatowski, Patrycja Mastalerz, Michał Flasiński
    Academic press:
    Biochimica et Biophysica Acta, Biomembranes (rok: 2015, tom: 1848, strony: 469-476), Wydawca: Elsevier
    Status:
    Published
  3. Antagonistic effects of alpha-tocopherol and ursolic acid on model bacterial membranes
    Authors:
    Marcin Broniatowski, Michał Flasiński, Katarzyna Hąc-Wydro
    Academic press:
    Biochimmica et Biophysica Acta Biomembranes (rok: 2015, tom: 1848, strony: 2154-2162), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2015.05.009 - link to the publication
  4. Grazing incidence diffraction studies of the interaction between ursane-type antimicrobial triterpenes and bacterial anionic phospholipids
    Authors:
    Marcin Broniatowski, Michał Flasiński, Paweł Wydro, Philippe Fontaine
    Academic press:
    Colloids and Surfaces B, Biointerfaces (rok: 2015, tom: 128, strony: 561-567), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2015.03.009 - link to the publication
  5. Incorporation of pentacyclic triterpenes into mitochondrial membrane - Studies on the interaction in model 2D lipid systems
    Authors:
    Michał Flasiński, Katarzyna Hąc-Wydro, Marcin Broniatowski
    Academic press:
    Journal of Physical Chemistry B (rok: 2014, tom: 118, strony: 12927-12937), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/jp508743j - link to the publication
  6. Langmuir monolayer studies of the interaction of monoamphiphilic pentacyclic triterpenes with anionic mitochondrial and bacterial membrane phospholipids - Searching for the most active terpene
    Authors:
    Marcin Broniatowski, Michał Flasiński, Katarzyna Zięba, Paweł Miśkowiec
    Academic press:
    Biochimica et Biophysica Acta, Biomembranes (rok: 2014, tom: 1838, strony: 2460-2472), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2014.05.009 - link to the publication