Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Hypoxia induced angiogenesis regulation by miR-200b, miR-429, and mir-200c.

2011/03/B/NZ3/04387

Keywords:

hypoxia angiogensis micro-RNA miRNA

Descriptors:

  • NZ3_1: Cell biology
  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Rafał Bartoszewski 

Number of co-investigators in the project: 6

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 790 314 PLN

Project start date (Y-m-d): 2012-08-06

Project end date (Y-m-d): 2016-02-05

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. luminometru płytkowego (format 96 i 24) (105 390 PLN)
  2. inkubator do hodowli komórkowych O2 i CO2.
  3. zamrazarka laboratoryjna -86 (40 383 PLN)
  4. System detekcji i analizy ilościowej metodą Western blot (WB) opartego na bezpośredniej detekcji chemiluminescencji i fluorescencji (wraz z komputerem i oprogramowaniem do obsługi aparatury). (100 000 PLN)
  5. wytrząsarka do hodowli bakterii.

Information in the final report

  • Publication in academic press/journals (5)
  1. RNAdigest: A Web-Based Tool for the Analysis and Prediction of Structure - Specific RNAse Digestion Results
    Authors:
    Madanecki P, Nozell S, Ochocka R, Collawn JF, Bartoszewski R
    Academic press:
    PLOS1 (rok: 2014, tom: 9, strony: PLoS ONE 9(5): e96759), Wydawca: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pone.0096759 - link to the publication
  2. Regulation of angiogenesis by hypoxia: the role of microRNA
    Authors:
    Piotr Madanecki, Niren Kapoor, Zsuzsa Bebok, Renata Ochocka, James F Collawn, Rafal Bartoszewski
    Academic press:
    Cellular & molecular biology letters (rok: 2013, tom: 18, strony: 47-57), Wydawca: SP Versita
    Status:
    Published
    DOI:
    10.2478/s11658-012-0037-0 - link to the publication
  3. miR-429 regulates the transition between Hypoxia-Inducible Factor (HIF)1A and HIF3A expression in human endothelial cells
    Authors:
    Anna Janaszak-Jasiecka, Sylwia Bartoszewska, Kinga Kochan, Arkadiusz Piotrowski, Leszek Kalinowski, Wojciech Kamysz, Renata J. Ochocka, Rafał Bartoszewski & James F. Collawn
    Academic press:
    Scientific Reports (rok: 2016, tom: 6, strony: 22775), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/srep22775 - link to the publication
  4. Regulation of the unfolded protein response by microRNAs
    Authors:
    Sylwia Bartoszewska, Kinga Kochan, Piotr Madanecki, Arkadiusz Piotrowski, Renata Ochocka, James F Collawn, Rafal Bartoszewski
    Academic press:
    Cellular & molecular biology letters (rok: 2013, tom: 18, strony: 555-678), Wydawca: SP Versita
    Status:
    Published
    DOI:
    10.2478/s11658-013-0106-z - link to the publication
  5. The hypoxia-inducible miR-429 regulates hypoxia-inducible factor- 1α expression in human endothelial cells through a negative feedback loop
    Authors:
    Sylwia Bartoszewska, Kinga Kochan, Arkadiusz Piotrowski, Wojciech Kamysz, Renata J Ochocka, James F Collawn, Rafal Bartoszewski
    Academic press:
    FASEB J (rok: 2015, ), Wydawca: FASEB
    Status:
    Accepted for publication
    DOI:
    10.1096/fj.14-267054 - link to the publication