Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Comprehensive prediction of cooperative regulatory elements in eukaryotic genomes

2011/03/N/NZ2/03177

Keywords:

transcription factors cooperative binding cell type specificity regulatory regions chromatin openness DNase-seq epigenetic marks

Descriptors:

  • NZ2_7: Bioinformatics
  • NZ2_8: Computational biology
  • NZ2_10: Biological systems analysis, modelling and simulation

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Aleksander Jankowski 

Number of co-investigators in the project: 2

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 79 100 PLN

Project start date (Y-m-d): 2012-09-18

Project end date (Y-m-d): 2014-09-17

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Notebook Sony Vaio SVS1312R9EB (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. SOXE transcription factors form selective dimers on non-compact DNA motifs through multifaceted interactions between dimerization and high-mobility group domains
    Authors:
    Yong-Heng Huang, Aleksander Jankowski, Kathryn S. E. Cheah, Shyam Prabhakar, Ralf Jauch
    Academic press:
    Scientific Reports (rok: 2015, tom: 5, strony: 10398), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/srep10398 - link to the publication
  2. Comprehensive prediction in 78 human cell lines reveals rigidity and compactness of transcription factor dimers
    Authors:
    Aleksander Jankowski, Ewa Szczurek, Ralf Jauch, Jerzy Tiuryn, Shyam Prabhakar
    Academic press:
    Genome Research (rok: 2013, tom: 23(8), strony: 1307-18), Wydawca: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1101/gr.154922.113 - link to the publication
  3. TACO: a general-purpose tool for predicting cell-type–specific transcription factor dimers
    Authors:
    Aleksander Jankowski, Shyam Prabhakar, Jerzy Tiuryn
    Academic press:
    BMC Genomics (rok: 2014, tom: 15, strony: 208), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/1471-2164-15-208 - link to the publication

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