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Determination of reaction rate constants between highly hydroxylated fullerenol C60(OH)26-33 and water radiolysis products and investigation of the mechanism of fullerenol action on human erythrocytes under oxidative stress generated by irradiation.

2011/03/N/ST4/01281

Keywords:

fullerenol pulse radiolysis ionizing radiation radioprotective erythrocytes cell membrane

Descriptors:

  • ST4_16: Ionic liquids
  • ST5_16:
  • ST4_2: Spectroscopic and spectrometric techniques

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Jacek Grębowski 

Number of co-investigators in the project: 2

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 43 420 PLN

Project start date (Y-m-d): 2012-09-05

Project end date (Y-m-d): 2013-09-04

Project duration:: 12 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  1. Fullerenol C60(OH)36 could associate to band 3 protein of human erythrocyte membranes.
    Authors:
    Jacek Grebowski, Anita Krokosz, Mieczyslaw Puchala
    Academic press:
    Biochimica et Biophysica Acta- Biomembranes (rok: 2013, tom: 1828, strony: 2007-2014), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2013.05.009. - link to the publication
  2. Fulerenol - właściwości i zastosowanie w naukach biomedycznych
    Authors:
    Jacek Grębowski, Paulina Każmierska, Anita Krokosz
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (Online). (rok: 2013, tom: 67, strony: 589-871), Wydawca: Index Copernicus
    Status:
    Published
    DOI:
    - - link to the publication
  3. Fullerenols as a new therapeutic approach in nanomedicine.
    Authors:
    Jacek Grebowski, Paulina Kazmierska, Anita Krokosz
    Academic press:
    BioMed Research International (rok: 2013, tom: 2013, strony: 45300), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2013/751913 - link to the publication

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