The role of the mGlu5-D2 heterodimeric receptor complexes in the extinction of drug seeking behavior associated with dependents to psichostimulants (cocaine and MDMA): behavioral and biomolecular analyses in rats

2011/03/D/NZ7/06295

Keywords

Descriptors

  • NZ3_5: Neurobiologia molekularna
  • NZ4_4: Patofizjologia ogólna
  • NZ5_3: Patogeneza chorób człowieka

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Instytut Farmakologii PAN, Instytut Farmakologii Polskiej Akademii Nauk

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Małgorzata Frankowska

Number of co-investigators in the project: 3

Call

SONATA 2 – announced on 2011-09-15

Amount awarded
768 570 PLN
Project start date
2012-08-06
Project end date
2016-04-05
Project duration
44 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Kołyska laboratoryjna.
  2. Sprzęt do detekcji i analizy makrocząsteczek znakowanych fluorescencyjnych; systemu do rozdziału i transferu białek. Cost: 250 000 PLN
  3. System do rozdziału i transferu białek z wyposazeniem.

Information in the final report

Publication in academic press/journals (1)

  1. Alternation in D2-like and mGlu5 receptor density caused by differing housing conditions during abstinence from cocaine self-administration in rats

    Authors:
    Małgorzata Frankowska, Joanna Miszkiel, Lucyna Pomierny-Chamioło, Bartosz Pomierny, Giuseooe Giannotti, Agata Suder, Małgorzata Filip
    Status:
    Accepted for publication

Articles in post-conference publications (1)

  1. Alterations in brain mGluR5 and D2 receptor density during MDMA abstinence in different living conditions in rats.

    Authors:
    Małgorzata Frankowska, Lucyna Pomierny-Chamioło, Joanna Miszkiel, Bartosz Pomierny, Małgorzata Filip
    Conference:
    XIX International Congress of the Polish Pharmacological Society: (year: 2015, pages: vol. 67, Supp. 1, 7), Publisher: Pharmacological Reports
    Date:
    conference 17-19 wrzesnia 2015 Swinoujscie
    Status:
    Published
    DOI:
    link to the publication

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