Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular classification of stage III cutaneous melanoma - genetic alterations in selected pathways and aCGH-based chromosomal loci in correlation to clinical-pathological features and patients outcome.

2011/03/B/NZ5/04513

Keywords:

malignant cutaneous melanoma lymph node metastases activating mutations molecular pathways aCGH

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ2_1: Molecular genetics
  • NZ5_7: Human disease treatment

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Piotr Rutkowski 

Number of co-investigators in the project: 15

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 895 000 PLN

Project start date (Y-m-d): 2012-08-22

Project end date (Y-m-d): 2015-08-21

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zamrażarka Med MDF-U700 (55 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (7)
  1. Molecular alterations in clinical stage III cutaneous melanoma correlation with clinical-pathological features and patient outcome
    Authors:
    Piotr Rutkowski, Aleksandra Gos, Monika Jurkowska, Tomasz Świtaj, Wirginiusz Dziewirska, Marcin Zdzienicki, Konrad Ptaszyński, Wanda Michej, Andrzej Tysarowski, Janusz A. Siedlecki
    Academic press:
    Oncology Letters (rok: 2014, tom: 8, strony: 47-54), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ol.2014.2122 - link to the publication
  2. The long-term results and prognostic significance of cutaneous melanoma surgery using sentinel node biopsy with triple technique
    Authors:
    Piotr Rutkowski, Konrad Szydłowski, Zbigniew I. Nowecki, Maciej Sałamacha, Tomasz Goryń, Beata Mitręga-Korab, Andrzej Pieńkowski, Wirginiusz Dziewirski, Marcin Zdzienicki
    Academic press:
    World Journal of Surgical Oncology (rok: 2015, tom: 13, strony: 299), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    brak - link to the publication
  3. Molecular characterization and patient outcome of melanoma nodal metastases and an unknown primary site
    Authors:
    Aleksandra Gos, Monika Jurkowska, Alexander van Akkooi, Caroline Robert, Hanna Kosela-Paterczyk, Senada Koljenović, Nyam Kamsukom, Wanda Michej, Arkadiusz Jeziorski, MD, Piotr Pluta, Cornelis Verhoef, Janusz A. Siedlecki, Alexander M.M. Eggermont, Piotr Rutkowski,
    Academic press:
    Annals of Surgical Oncology (rok: 2014, tom: 21, strony: 4317-23), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1245/s10434-014-3799-y - link to the publication
  4. Comparison between two widely used laboratory methods in BRAF V600 mutation detection in a large cohort of clinical samples of cutaneous melanoma metastases to the lymph nodes
    Authors:
    Monika Jurkowska, Aleksandra Gos, Konrad Ptaszyński, Wanda Michej, Andrzej Tysarowski, Renata Zub, Janusz A. Siedlecki, Piotr Rutkowski
    Academic press:
    International Journal of Clinical and Experimental Pathology (rok: 2015, tom: 8, strony: 8487-8493), Wydawca: e-Century Publishing Corporation
    Status:
    Published
    DOI:
    brak - link to the publication
  5. Subcutaneous metastases from melanoma: a discussion of clinical experience.
    Authors:
    Rutkowski P, Zdzienicki M, Kozak K.
    Academic press:
    Melanoma Management (rok: 2014, tom: 1, strony: 31-40), Wydawca: Future Medicine
    Status:
    Published
    DOI:
    10.2217/mmt.14.1 - link to the publication
  1. Charakterystyka molekularna i wyniki leczenia chorych na czerniaki o nieznanym ognisku pierwotnych z przerzutami do węzłów chłonnych.
    Authors:
    Piotr Rutkowski, Aleksandra Gos, Monika Jurkowska, Alexander van Akkooi, Caroline Robert, Piotr Pluta, Marcin Zdzienicki, Wirginiusz Dziewirski, Senada Koljenović, Nyam Kamsukom, Wanda Michej, Christiane Voit, Janusz A. Siedlecki, Alexander Eggermont, Arkadiusz Jeziorski.
    Conference:
    XIX Zjazd Polskiego Towarzystwa Chirurgii Onkologicznej (rok: 2013, ), Wydawca: ViaMedica
    Data:
    konferencja 23-25 maja
    Status:
    Published
  2. Sanger Sequencing vs.the Cobas BRAF V600 Mutation Test in Stage III cutaneous melanoma BRAF mutation detection efficacy
    Authors:
    A. Gos, M. Jurkowska, J.A. Siedlecki, W. Michej, K. Ptaszyński, W Olszewski, K. Wiater, T. Świtaj, H. Koseła, P. Rutkowski
    Conference:
    19th Congress of the Polish Society of Pathologists "Advances in pathomorphology" (rok: 2013, ), Wydawca: Termedia Wydawnictwo Medyczne
    Data:
    konferencja 6-9 June 2013
    Status:
    Published
  3. Comparison between two widely used laboratory methods in BRAF V600 mutation detection rate in FFPE clinical samples of stage III cutaneous melanoma metastases to the lymph nodes
    Authors:
    A. Gos, M. Jurkowska, J.A. Siedlecki, W. Michej, K. Wiater, T. Switaj, H. Kosela, P. Rutkowski
    Conference:
    Th 17th ECCO-38thESMO-32nd ESRTO European Cancer Congress (rok: 2013, ), Wydawca: European CanCer Organization
    Data:
    konferencja 27 September- 1 October
    Status:
    Published
    DOI:
    link to the publication
  4. Molecular Characterization and Patient Outcome of Unknown Primary Melanoma with Nodal Metastases
    Authors:
    A.Gos, A.Van Akkooi, C.Robert, M.Jurkowska, S.Koljenovic, N.Kamsukom, W.Michej, A.Jeziorski, C.Voit, H.Kosela, P.Pluta, J.Siedlecki, A. Eggermont, P. Rutkowski
    Conference:
    Society of Surgical Oncology 66th Annual Cancer Symposium (rok: 2013, ), Wydawca: Society of Surgical Oncology
    Data:
    konferencja March 6-9, 2013
    Status:
    Published
  5. Copy number alterations determined by arrayCGH influence prognosis in stage III metastatic melanomas.
    Authors:
    Monika Jurkowska, Ewa Mierzejewska, Katarzyna Sobecka, Aleksandra Gos, Hanna Koseła-Paterczyk, Artur Kowalik, Beata Nowakowska, Janusz A. Siedlecki, Piotr Rutkowski,
    Conference:
    Society of Surgical Oncology 68th Annual Cancer Symposium (rok: 2016, ), Wydawca: Society of Surgical Oncology
    Data:
    konferencja 2-5 March
    Status:
    Published
    DOI:
    link to the publication
  6. Charakterystyka molekularna i wyniki leczenia u pacjentów chorych na czerniaka o nieznanym ognisku pierwotnym z przerzutami do węzłów chłonnych.
    Authors:
    Rutkowski P, Gos A, Koseła H, van Akkooi A, Robert C, Jurkowska M, Koljenovic S, Kamsukom N, Michej W, Jeziorski A, Voit C, Pluta P, Siedlecki JA, Eggermont A.
    Conference:
    XVI Kongres Polskiego Towarzystwa Onkologii Klinicznej (rok: 2013, ), Wydawca: Polskie Towarzystwo Onkologii Klinicznej
    Data:
    konferencja 29-31 sierpnia
    Status:
    Published
  7. The next generation sequencing (NGS) analysis of selected genes and pathways in clinical stage III cutaneous melanoma
    Authors:
    I. Lugowska, E. Mierzejewska, A. Kowalik, A. Gos, S. Zięba, J. Siedlecki, H. Kosela-Paterczyk, A. Szumera-Ciećkiewicz, M. Jurkowska, P. Rutkowski
    Conference:
    The 18th ECCO-40th ESMO European Cancer Congress (rok: 2015, ), Wydawca: brak
    Data:
    konferencja 25-29 September
    Status:
    Published

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