Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of proteolytic cleavage in molecular functions fulfilled by MCPIP.

2011/03/N/NZ1/01193

Keywords:

posttranslational modifications molecular regulation of the inflammation

Descriptors:

  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Łukasz Skalniak 

Number of co-investigators in the project: 3

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 234 300 PLN

Project start date (Y-m-d): 2012-09-03

Project end date (Y-m-d): 2014-09-02

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Automatyczny licznik komórek (25 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. MCPIP1 contributes to the toxicity of proteasome inhibitor MG-132 in HeLa cells by the inhibition of NF-κB.
    Authors:
    Skalniak L, Dziendziel M, Jura J
    Academic press:
    Mol Cell Biochem (rok: 2014, tom: 395, strony: 253-263), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11010-014-2134-z - link to the publication
  2. Proteasome inhibitor MG-132 induces MCPIP1 expression.
    Authors:
    Skalniak L, Koj A, Jura J
    Academic press:
    FEBS Journal (rok: 2013, tom: 280(11), strony: 2665-2674), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/febs.12264 - link to the publication
  1. The role of MCPIP1 in the inflammatory reaction as an example of complex regulation of gene expression
    Authors:
    Jolanta Jura, Łukasz Skalniak, Barbara Lipert, Janusz Ligęza, Aleksander Koj
    Conference:
    48 Zjazd Polskiego Towarzystwa Biochemicznego (rok: 2013, ), Wydawca: Polskie Towarzystwo Biochemiczne/Acta Biochimica Polonica Supplement 1, 2013
    Data:
    konferencja 02-05.09.2013
    Status:
    Published
    DOI:
    link to the publication
  2. MCPIP1: regulating the regulator
    Authors:
    Skalniak, L; Dziendziel, M; Lipert, B; Plesnar, E; Mak, P; Kliza, K; Wojtowicz, E; Benedyk, M; Chalastanis, A; Mizgalska, D; Murzyn, K; Koj, A; Klein, A; Jura, J
    Conference:
    22nd IUBMB Congress/37th FEBS Congress (rok: 2012, ), Wydawca: Wiley/FEBS JOURNAL, vol 279, Issue Supplement s1
    Data:
    konferencja 04-09.09.2012
    Status:
    Published
    DOI:
    link to the publication

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