Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Senescence of glial tumour cells in vitro - elucidation of the mechanism and its practical implications

2011/03/N/NZ1/06534

Keywords:

senescence CNS tumours glioma cell culture

Descriptors:

  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Nauk Biomedycznych i Kształcenia Podyplomowego

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Ewelina Stoczyńska-Fidelus 

Number of co-investigators in the project: 3

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 243 300 PLN

Project start date (Y-m-d): 2012-09-26

Project end date (Y-m-d): 2015-09-25

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Wytrząsarka typu vortex (1 500 PLN)
  2. Mierni k pH (4 000 PLN)
  3. Wytrząsrka z inkubatorem (9 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. Spontaneous in vitro senescence of glioma cells confirmed by an antibody against IDH1R132H
    Authors:
    Stoczynska-Fidelus E, Och W, Rieske P, Bienkowski M, Banaszczyk M, Winiecka-Klimek M, Zieba J, Janik K, Rosiak K, Treda C, Stawski R, Radomiak-Zaluska A, Piaskowski S.
    Academic press:
    Anticancer Research (rok: 2014, tom: 34(6), strony: 2859-2868), Wydawca: International Institute of Anticancer Research (IIAR)
    Status:
    Published
  2. The failure in the stabilization of glioblastoma-derived cell lines: spontaneous in vitro senescence as the main culprit
    Authors:
    Stoczynska-Fidelus E, Piaskowski S, Bienkowski M, Banaszczyk M, Hulas-Bigoszewska K, Winiecka-Klimek M, Radomiak-Zaluska A, Och W, Borowiec M, Zieba J, Treda C, Rieske P.
    Academic press:
    PLoS One (rok: 2014, tom: 9(1), strony: e81736 (1-15)), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0087136 - link to the publication
  1. IN VITRO SENESCENCE OF GLIOBLASTOMA CELLS?
    Authors:
    Ewelina Stoczynska-Fidelus, Michal Bienkowski, Sylwester Piaskowski, Mateusz Banaszczyk, Marta Winiecka, Jolanta Zieba, Krystyna Hulas-Bigoszewska, Anna Radomiak-Zaluska, Piotr Rieske
    Conference:
    5th international conference on drug discovery and therapy (ICDDT), Dubai, United Arab Emirates (rok: 2013, ), Wydawca: Eureka Science
    Data:
    konferencja 18- 21 February 2013
    Status:
    Published
  2. Why do glioma cell lines represent only minor fraction of these tumors?
    Authors:
    Piotr Rieske, Ewelina Stoczynska-Fidelus
    Conference:
    Conference of the Team of Oncologic Neuropathology of The Committee on Neurological Sciences, Polish Academy of sciences "Diagnosis and treatment of gliomas in the era of molecular biology", Warsaw, Poland (rok: 2013, ), Wydawca: Mossakowski Medical Research Centre, Polish Academy of Sciences
    Data:
    konferencja 41565
    Status:
    Published
  3. 3.IS SENESCENCE THE MAIN MECHANISM RESPONSIBLE FOR GLIOBLASTOMA CELL LINE STABILIZATION FAILURE?
    Authors:
    Ewelina Stoczynska-Fidelus, Michal Bienkowski, Sylwester Piaskowski, Mateusz Banaszczyk, Marta Winiecka, Jolanta Zieba, Krystyna Hulas-Bigoszewska, Anna Radomiak-Zaluska, Piotr Rieske
    Conference:
    International Conference on Visualizing of senescent cells in vitro and in vivo (Seneca 2012 Conference, Biogerontological Meetings at the Nencki Institute of Experimental Biology in the framework of FP7 EU THEME REGPOT (Research Potential)), Warsaw, Poland (rok: 2012, ), Wydawca: Nencki Institute of Experimental Biology
    Data:
    konferencja 15-16 December 2012
    Status:
    Published