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Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Search for biological background of diversified vulnerability to psychoactive substances in rats on the basis of amphetamine sensitization

2011/03/B/NZ4/02385

Keywords:

amphetamine sensitization ultrasonic vocalization individual differences biological factors in dependence

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Psychiatrii i Neurologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Taracha 

Number of co-investigators in the project: 7

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 451 562 PLN

Project start date (Y-m-d): 2012-10-08

Project end date (Y-m-d): 2016-04-07

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. detektor Elektrochemiczny (8 902 PLN)
  2. upgrade oprogramowania Cell Fdo wersji CellSens Dimension wraz z komputerem (43 000 PLN)
  3. rozbudowa systemu do pomiaru wokalizacji ultradźwiękowej (40 200 PLN)
  4. Mikroskop Olympus (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. N-acetyl cysteine does not modify the sensitization of the rewarding effect of amphetamine as assessed with frequency-modulated 50-kHz vocalization in the rat.
    Authors:
    Taracha E, Kaniuga E, Chrapusta SJ, Boguszewski PM, Lehner M, Krząścik P, Płaźnik A.
    Academic press:
    Behav Brain Res (rok: 2014, tom: 280, strony: 141-8), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbr.2014.12.005 - link to the publication
  2. Poor sensitization of 50-kHz vocalization response to amphetamine predicts rat susceptibility to self-administration of the drug
    Authors:
    Ewa Taracha, Ewelina Kaniuga, Edyta Wyszogrodzka, Adam Płaźnik, Roman Stefański, Stanisław J. Chrapusta.
    Academic press:
    Psychopharmacology (rok: 2016, tom: 1648, strony: 356-364), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00213-016-4328-4 - link to the publication
  3. Rats showing low and high sensitization of frequency-modulated 50-kHz vocalization response to amphetamine differ in amphetamine-induced brain Fos expression.
    Authors:
    Ewa Taracha, Ewelina Kaniuga, Tomasz Stępień, Teresa Wierzba-Bobrowicz, Adam Płaźnik, Stanisław J. Chrapusta.
    Academic press:
    Brain Research (rok: 2016, tom: 1648, strony: 356-364), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.brainres.2016.08.008 - link to the publication
  4. Diverging frequency-modulated 50-kHz vocalization, locomotor activity and conditioned place preference effects in rats given repeated amphetamine treatment.
    Authors:
    Taracha E, Kaniuga E, Chrapusta SJ, Maciejak P, Sliwa L, Hamed A, Krząścik P.
    Academic press:
    Neuropharmacology (rok: 2014, tom: 83, strony: 128-36), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neuropharm.2014.04.008 - link to the publication
  5. High-anxiety rats are less sensitive to the rewarding affects of amphetamine on 50kHz USV
    Authors:
    Lehner MH, Taracha E, Kaniuga E, Wisłowska-Stanek A, Wróbel J, Sobolewska A, Turzyńska D, Skórzewska A, Płaźnik A.
    Academic press:
    Behav Brain Res. (rok: 2014, tom: 15, strony: 234-42), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbr.2014.09.011 - link to the publication

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