Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Function of DNA methylation and CNV-type polymorphisms of genes encoding metalloproteinase and their tissue inhibitors in COPD development.

2011/03/B/NZ5/05790

Keywords:

genetics COPD metalloproteinases tissue inhibitors of metalloproteinases CNV DNA methylation

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_1: Etiology of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Politechnika Opolska, Wydział Wychowania Fizycznego i Fizjoterapii

woj. opolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Edyta Majorczyk 

Number of co-investigators in the project: 7

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 489 000 PLN

Project start date (Y-m-d): 2012-08-22

Project end date (Y-m-d): 2015-08-21

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Termocykler (30 000 PLN)
  2. Zamrazarka niskotemperaturowa (40 000 PLN)
  3. Drukarka termiczna (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. CXCL8 (interleukin 8)--the key inflammatory mediator in chronic obstructive pulmonary disease?
    Authors:
    Iwona Gilowska
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (Online) (rok: 2014, tom: 68, strony: 842-850), Wydawca: Index Copernicus International
    Status:
    Published
  2. Impact of Matrix Metalloproteinase 9 on COPD Development in Polish Patients: Genetic Polymorphism, Protein Level, and Their Relationship with Lung Function
    Authors:
    Iwona Gilowska, Łukasz Kasper, Katarzyna Bogacz, Jan Szczegielniak, Teresa Szymasek, Marta Kasper, Marcin Czerwinski, Krzysztof Sładek, Edyta Majorczyk
    Academic press:
    Biomed Research International (rok: 2018, tom: 2018, strony: ID 6417415), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2018/6417415 - link to the publication
  3. The role of MMP-12 gene polymorphism -82A>G (rs2276109) in immunopathology of COPD in Polish patients: a case control study
    Authors:
    Iwona Gilowska, Edyta Majorczyk, Łukasz Kasper, Katarzyna Bogacz, Jan Szczegielniak, Marta Kasper, Jacek Kaczmarski, Aleksandra Skomudek, Marcin Czerwinski, Krzysztof Sładek
    Academic press:
    BMC Medical Genetics , Wydawca: Springer Nature
    Status:
    Submitted
  1. Impact of -1562 C/T polymorphism of MMP9 gene on COPD susceptibility in Polish patients
    Authors:
    Iwona Gilowska, Lukasz Kasper, Katarzyna Bogacz, Jan Szczegielniak, Tomasz Dybek, Krzysztof Sladek, Marcin Czerwinski, Edyta Majorczyk
    Conference:
    ERS International Congress 2014 (rok: 2014, ), Wydawca: European Respiratory Society
    Data:
    konferencja 6-10 września 2014 r
    Status:
    Published