Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Effect of melatonin on the choroid plexus response to immune stress in ewes

2011/03/B/NZ9/00118

Keywords:

melatonin choroid plexus tight junction proteins cytokines immune stress ewes

Descriptors:

  • NZ9_2: Animal production

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Instytut Rozrodu Zwierząt i Badań Żywności PAN

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Janina Skipor 

Number of co-investigators in the project: 5

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 429 000 PLN

Project start date (Y-m-d): 2012-08-21

Project end date (Y-m-d): 2016-02-20

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (6)
  1. PROFILE OF TOLL-LIKE RECEPTOR mRNA EXPRESSION IN THE CHOROID PLEXUS IN ADULT EWES
    Authors:
    Janina Skipor, Aleksandra Szczepkowska, Marta Kowalewska, Andrzej P. Herman, Paweł Lisiewski
    Academic press:
    Acta Veterinaria Hungarica (rok: 2015, tom: 63(1), strony: 69-78), Wydawca: Akademiai Kiado
    Status:
    Published
    DOI:
    10.1556/AVet.2014.027 - link to the publication
  2. Melatonin from slow-release implants did not influence the gene expression of the lipopolysaccharide receptor complex in the choroid plexus of seasonally anoestrous adult ewes subjected or not to a systemic inflammatory stimulus
    Authors:
    Kowalewska M, Szczepkowska A, Herman AP, Pellicer-Rubio MT, Jalynski M, Skipor J
    Academic press:
    Small Ruminant Research (rok: 2017, tom: 147, strony: 45298), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.smallrumres.2016.11.018 - link to the publication
  3. Basic and TLR-4-mediated gene expression of inflammatory cytokines and their receptors in the choroid plexus in ewes: effect of melatonin from slow-release implants
    Authors:
    Kowalewska M, Herman AP, Szczepkowska A, Skipor J
    Academic press:
    Mediators of Inflammation , Wydawca: Hindawi
    Status:
    Submitted
  1. Does melatonin affect mRNA expression of toll-like receptors in the ovine choroid plexus?
    Authors:
    Janina Skipor, Aleksandra Szczepkowska, Andrzej P Herman, Marek Jalynski
    Conference:
    16th International Symposium on Signal Transduction in the Blood-brain Barriers (rok: 2013, ), Wydawca: Maria Deli and Istvan Krizbai
    Data:
    konferencja 12-14 września
    Status:
    Published
  2. Wpływ endotoksyny Escherichia coli na ekspresję mRNA komopleksu Toll-like receptora 4 w splocie naczyniówkowym komór mózgu u owiec
    Authors:
    Marta Kowalewska, Aleksandra Szczepkowska, Andrzej P. Herman, Marek Jałyński, Janina Skipor
    Conference:
    Konferencja szkoleniowo-naukowa Polskiego Towarzystwa Toksykologicznego (rok: 2014, ), Wydawca: Wydawnictwo UWM
    Data:
    konferencja 16-19 września
    Status:
    Published
  3. CSF IL-1beta level and brain barriers permeability in ewes during systemic inflammation: effect of melatonin from slow release implants
    Authors:
    Kowalewska M, Szczepkowska A, Majewska A, Misztal T, Herman AP, Jalyński M, Zabek K, Skipor
    Conference:
    19th International Symposium on Signal Transduction at the Blood-Brain Barriers (rok: 2016, ), Wydawca: Birger Brodin
    Data:
    konferencja 14-16 września
    Status:
    Published
  4. Wpływ lipopolisacharydu i melatoniny na ekspresję mRNA metaloproteinaz i ich inhibitorów w splocie naczyniówkowym komór mózgu u owiec
    Authors:
    Marta Kowalewska, Aleksandra Szczepkowska, Przemysław Gilun, Jnina Skipor
    Conference:
    Warsztaty Naukowe Fizjologiczne Mechanizmy Wzrostu, Rozwoju i Rozrodu Zwierząt (rok: 2014, ), Wydawca: Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN
    Data:
    konferencja 23-24 października
    Status:
    Published
  5. Effect of melatonin implantation on the lipopolysaccharide-induced cytokines and their receptors expression in the choroid plexus of adult ewes
    Authors:
    Marta Kowalewska, Andrzej P. Herman, Aleksandra Szczepkowska, Janina Skipor
    Conference:
    17th International Symposium on Signal Transduction at the Blood -brain and Blood-retina Barriers (rok: 2014, ), Wydawca: Matthew Campbell, Peter Humphries, Sarah Doyle and Andrew Knox
    Data:
    konferencja 11-13 września
    Status:
    Published
  6. Exogenous melatonin affects claudins in the choroid plexus of control and lipopolysaccharide treated ewes
    Authors:
    Aleksandra Szczepkowska, Marta Kowalewska, Janina Skipor
    Conference:
    11th International Conference on Cerebral Vascular Biology - BBB Signalling (rok: 2015, ), Wydawca: Pierre-Olivier Couraud, Xavier Declèves, Jean-Michel Scherrmann
    Data:
    konferencja 6-9 lipca
    Status:
    Published