Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Identification of brain specific non-coding microRNAs in mice: 1 - regulating a synaptic plasticity in learning&memory and 2 - controlling an Insulin-mTOR signalling pathway in neurons responsible for development of obesity syndrome

2011/01/D/NZ4/03744

Keywords:

microRNA transgenic mice Cre/loxP system Dicer learning&memory obesity

Descriptors:

  • NZ4_9: Systems neurobiology
  • NZ3_5: Molecular neurobiology
  • NZ4_10: Neuroimaging and computational neuroscience

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Witold Konopka 

Number of co-investigators in the project: 3

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 1 000 000 PLN

Project start date (Y-m-d): 2012-06-29

Project end date (Y-m-d): 2017-06-28

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Przystawka do maszyny PCR.
  2. Zestaw do elektroforezy i transferu białek.
  3. Maszyna PCR (20 000 PLN)
  4. Termomixer.
  5. Zestaw komputerowy (2 szt.) (15 000 PLN)
  6. Zestaw do elektroforezy DNA (16 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Book publications / chapters in book publications (1)
  1. Impaired rRNA synthesis triggers homeostatic responses in hippocampal neurons.
    Authors:
    Kiryk A, Sowodniok K, Kreiner G, Rodriguez-Parkitna J, Sönmez A, Górkiewicz T, Bierhoff H, Wawrzyniak M, Janusz AK, Liss B, Konopka W, Schütz G, Kaczmarek L, Parlato R.
    Academic press:
    Front Cell Neurosci (rok: 2013, tom: 7, strony: 207), Wydawca: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fncel.2013.00207 - link to the publication
  2. Enhanced fear memory follow ing TDP-43 neuronal depletion
    Authors:
    Koza P, Beroun A, Konopka A, Górkiewicz T, Torres JC, Bulska E, Knapska E, Kaczmarek L, Konopka W
    Academic press:
    Nature Communications , Wydawca: Nature Publishing Group
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. Hypothalamic miR-103 protects from hyperphagic obesity in mice
    Authors:
    Vinnikov IA, Hajdukiewicz K, Reymann J, Beneke J, Czajkowski R, Roth LC, Novak M, Roller A, Dörner N, Starkuviene V, Theis FJ, Erfle H, Schütz G, Grinevich V, Konopka W
    Academic press:
    J Neurosci (rok: 2014, tom: 34(32), strony: 10659-74), Wydawca: Society for Neuroscience
    Status:
    Published
    DOI:
    10.1523/JNEUROSCI.4251-13.2014 - link to the publication
  1. Continuous Delivery of Oligonucleotides into the Brain
    Authors:
    Vinnikov IA, Domanskyi A, Konopka W.
    Book:
    MicroRNA Technologies (Springer Protocols) (rok: 2017, tom: 128, strony: 89-117), Wydawca: Springer New York
    Status:
    Published

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