Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Complex cytogenetic and molecular analysis of sperm cells from chromosome translocation carriers (CT) with reproductive failures

2011/01/B/NZ2/04819

Keywords:

chromosome translocations male infertility sperm DNA

Descriptors:

  • NZ2_1:
  • NZ2_5:
  • NZ2_11:

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Genetyki Człowieka PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maciej Krzysztof Kurpisz 

Number of co-investigators in the project: 10

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 392 600 PLN

Project start date (Y-m-d): 2011-12-06

Project end date (Y-m-d): 2014-12-05

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Oprogramowanie graficzne (5 500 PLN)
  2. Zamrażarka do -20 stopniC (4 000 PLN)
  3. Drukarka OKI.
  4. Komora laminarna z pionowym przepływem powietrza (II klasa bezpieczeństwa (25 000 PLN)
  5. Mikrowirówka laboratoryjna z rotorem horyzontalnym i stałokątnym oraz z adapterami na probówki (25 000 PLN)
  6. Komputer stacjonarny (5 500 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (1)
  1. Mutations in X-linked TEX11 cause meiotic arrest and azoospermia in infertile men.
    Authors:
    Yatsenko AN, Georgiadis AP, Röpke A, Berman AJ, Jaffe T, Olszewska M, Westernströer B, Sanfillippo J, Kurpisz M, Rajkovic AR, Yatsenko SA, Kliesch S, Schlatt S, Tüttelmann F.
    Academic press:
    New Engl J Med (rok: 2015, tom: 372(22), strony: 2097-2107), Wydawca: Massachusetts Medical Society
    Status:
    Published
    DOI:
    10.1056/NEJMoa1406192 - link to the publication
  2. Cytogenetic and molecular analyses of de novo translocation dic(9;13)(p11.2;p12) in an infertile male.
    Authors:
    Wiland E, Olszewska M, Georgiadis A, Huleyuk N, Panasiuk B, Zastavna D, Yatsenko SA, Jedrzejczak P, Midro AT, Yatsenko AN, Kurpisz M.
    Academic press:
    Molecular Cytogenetics (rok: 2014, tom: 7, strony: 14), Wydawca: BIOMED CENTRAL LTD
    Status:
    Published
    DOI:
    10.1186/1755-8166-7-14. - link to the publication
  3. Sperm FISH and chromatin integrity in spermatozoa from a t(6;10;11) carrier
    Authors:
    Olszewska M, Huleyuk N, Fraczek M, Zastavna D, Wiland E, Kurpisz M.
    Academic press:
    Reproduction (rok: 2014, tom: 147, strony: 659-670), Wydawca: BIOSCIENTIFICA LTD
    Status:
    Published
    DOI:
    10.1530/REP-13-0533 - link to the publication
  4. Chromatin structure analysis of spermatozoa from reciprocal chromosome translocation carriers (RCT) with known meiotic segregation patterns
    Authors:
    Olszewska M, Fraczek M, Huleyuk N, Czernikiewicz A, Wiland E, Boksa M, Zastavna D, Panasiuk B, Midro AT, Kurpisz M.
    Academic press:
    Reproductive Biology (rok: 2013, tom: 13, strony: 209-220), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.repbio.2013.06.002 - link to the publication
  5. Recurrence risks for different pregnancy outcomes and meiotic segregation analysis of spermatozoa in carriers of t(1;11)(p36.22;q12.2).
    Authors:
    Midro AT, Panasiuk B, Stasiewicz-Jarocka B, Olszewska M, Wiland E, Myśliwiec M, Kurpisz M, Shaffer LG, Gajecka M.
    Academic press:
    J Hum Genet (rok: 2014, tom: 59(1), strony: 667-674), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/jhg.2014.92 - link to the publication
  6. Mechanizmy powstawania translokacji chromosomowych.
    Authors:
    Olszewska M, Kurpisz M.
    Status:
    Accepted for publication
  1. Sperm fractionation in reciprocal translocation carrier t(15;17) – association with sperm chromosome/chromatin content
    Authors:
    Olszewska M, Wiland E, Fraczek M, Kurpisz M.
    Conference:
    9th European Cytogenetics Conference (rok: 2013, ), Wydawca: Chromosome Research
    Data:
    konferencja 29.06.-02.07.2013
    Status:
    Published

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