Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Complex cytogenetic and molecular analysis of sperm cells from chromosome translocation carriers (CT) with reproductive failures

2011/01/B/NZ2/04819

Keywords:

chromosome translocations male infertility sperm DNA

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ2_5: Cell genetics
  • NZ2_11: Genetic epidemiology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Genetyki Człowieka PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maciej Kurpisz 

Number of co-investigators in the project: 10

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 392 600 PLN

Project start date (Y-m-d): 2011-12-06

Project end date (Y-m-d): 2014-12-05

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Oprogramowanie graficzne (5 500 PLN)
  2. Zamrażarka do -20 stopniC (4 000 PLN)
  3. Drukarka OKI.
  4. Komora laminarna z pionowym przepływem powietrza (II klasa bezpieczeństwa (25 000 PLN)
  5. Mikrowirówka laboratoryjna z rotorem horyzontalnym i stałokątnym oraz z adapterami na probówki (25 000 PLN)
  6. Komputer stacjonarny (5 500 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (3)
  1. Sperm FISH and chromatin integrity in spermatozoa from a t(6;10;11) carrier
    Authors:
    Olszewska M, Huleyuk N, Fraczek M, Zastavna D, Wiland E, Kurpisz M.
    Academic press:
    Reproduction (rok: 2014, tom: 147, strony: 659-670), Wydawca: BIOSCIENTIFICA LTD
    Status:
    Published
    DOI:
    10.1530/REP-13-0533 - link to the publication
  2. Chromatin structure analysis of spermatozoa from reciprocal chromosome translocation carriers (RCT) with known meiotic segregation patterns
    Authors:
    Olszewska M, Fraczek M, Huleyuk N, Czernikiewicz A, Wiland E, Boksa M, Zastavna D, Panasiuk B, Midro AT, Kurpisz M.
    Academic press:
    Reproductive Biology (rok: 2013, tom: 13, strony: 209-220), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.repbio.2013.06.002 - link to the publication
  3. Mechanizmy powstawania translokacji chromosomowych.
    Authors:
    Olszewska M, Kurpisz M.
    Academic press:
    Na pograniczu chemii i biologii (rok: 2015, tom: XXXII, strony: 0), Wydawca: Wydawnictwo Naukowe Uniwersytetu im. Adama Mickiewicza w Poznaniu
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  4. Recurrence risks for different pregnancy outcomes and meiotic segregation analysis of spermatozoa in carriers of t(1;11)(p36.22;q12.2).
    Authors:
    Midro AT, Panasiuk B, Stasiewicz-Jarocka B, Olszewska M, Wiland E, Myśliwiec M, Kurpisz M, Shaffer LG, Gajecka M.
    Academic press:
    J Hum Genet (rok: 2014, tom: 59(1), strony: 667-674), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/jhg.2014.92 - link to the publication
  5. FISH and array CGH characterization of de novo der(Y)(q11.221;p11.31) in an azoospermic male.
    Authors:
    Wiland E, Yatsenko AN, Kishore A, Stanczak H, Zdarta A, Olszewska M, Wolski JK, Kurpisz M.
    Academic press:
    Reprod Biomed Online (rok: 2015, ), Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication
  6. Do the chromosome structural aberrations may affect global methylation status of sperm DNA?
    Authors:
    Olszewska M, Barciszewska MZ, Fraczek M, Huleyuk N, Chernykh VB, Zastavna D, Barciszewski J, Kurpisz M.
    Academic press:
    Asian J Androl (rok: 2015, ), Wydawca: Shanghai Materia Medica, Shanghai Jiao Tong University
    Status:
    Submitted
    DOI:
    brak - link to the publication
  7. Cytogenetic and molecular analyses of de novo translocation dic(9;13)(p11.2;p12) in an infertile male.
    Authors:
    Wiland E, Olszewska M, Georgiadis A, Huleyuk N, Panasiuk B, Zastavna D, Yatsenko SA, Jedrzejczak P, Midro AT, Yatsenko AN, Kurpisz M.
    Academic press:
    Molecular Cytogenetics (rok: 2014, tom: 7, strony: 14), Wydawca: BIOMED CENTRAL LTD
    Status:
    Published
    DOI:
    10.1186/1755-8166-7-14. - link to the publication
  8. Mutations in X-linked TEX11 cause meiotic arrest and azoospermia in infertile men.
    Authors:
    Yatsenko AN, Georgiadis AP, Röpke A, Berman AJ, Jaffe T, Olszewska M, Westernströer B, Sanfillippo J, Kurpisz M, Rajkovic AR, Yatsenko SA, Kliesch S, Schlatt S, Tüttelmann F.
    Academic press:
    New Engl J Med (rok: 2015, tom: 372(22), strony: 2097-2107), Wydawca: Massachusetts Medical Society
    Status:
    Published
    DOI:
    10.1056/NEJMoa1406192 - link to the publication
  1. Meiotic Segregation Pattern and Chromatin Structure Analysis of Spermatozoa from a Carrier with Complex Chromosome Rearrangement (CCR) t(6;10;11)(q25;q24;q23) – Case Report.
    Authors:
    Olszewska M, Huleyuk N, Zastavna D, Wiland E, Kurpisz M.
    Conference:
    42nd Biennial American Cytogenetics Conference, San Antonio, TX, USA (rok: 2012, ), Wydawca: Cytogenet Genome Res.
    Data:
    konferencja April 19–22
    Status:
    Published
  2. Sperm fractionation in reciprocal translocation carrier t(15;17) – association with sperm chromosome/chromatin content
    Authors:
    Olszewska M, Wiland E, Fraczek M, Kurpisz M.
    Conference:
    9th European Cytogenetics Conference (rok: 2013, ), Wydawca: Chromosome Research
    Data:
    konferencja 29.06.-02.07.2013
    Status:
    Published
  3. Multiple mutations discovered in a familial case of azoospermia using whole exome sequencing (WES)
    Authors:
    Yatsenko AN, Georgiadis AP, McGuire MM, Zorrilla M, Bunce KD, Peters D, Rajkovic A, Olszewska M, Kurpisz M.
    Conference:
    29th Annual Meeting of the European Society of Human Reproduction and Embryology (rok: 2013, ), Wydawca: Human Reproduction
    Data:
    konferencja 07.-10.07.2013
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy