Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Genetic predictive factors in restenosis

2011/01/D/NZ5/04387

Keywords:

percutaneous coronary intervention stent restenosis polymorphism genetics

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases
  • NZ5_1: Etiology of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

ŚLĄSKIE CENTRUM CHORÓB SERCA

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Tadeusz Osadnik 

Number of co-investigators in the project: 8

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 250 000 PLN

Project start date (Y-m-d): 2011-12-16

Project end date (Y-m-d): 2015-02-15

Project duration:: 38 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Fluorymetr - Qubit 2.0 (16 000 PLN)
  2. System dokumentacji żeli (18 000 PLN)
  3. Termocykler Veriti - Life Technologies (18 000 PLN)
  4. Zestaw do Elektroforezy VWR (2 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  1. Functional polymorphism rs710218 in the gene coding GLUT1 protein is associated with in-stent restenosis
    Authors:
    Tadeusz Osadnik, Joanna Strzelczyk, Kamil Bujak, Rafał Reguła, Jarosław Wasilewski, Martyna Frączek, Anna Kurek, Marcin Gawlita, Małgorzata Gonera, Marek Gierlotka, Andrzej Lekston, Michał Hawranek, Andrzej Wiczkowski, Zofia Ostrowska, Lech Poloński, Mariusz Gąsior
    Academic press:
    Biomarkers in Medicine (rok: 2015, tom: 9, strony: 743-750), Wydawca: Future Medicine
    Status:
    Published
    DOI:
    10.2217/BMM.15.36 - link to the publication
  2. The Relationships between Polymorphisms in Genes Encoding the Growth Factors TGF-β1, PDGFB, EGF, bFGF and VEGF-A and the Restenosis Process in Patients with Stable Coronary Artery Disease Treated with Bare Metal Stent.
    Authors:
    Osadnik T, Strzelczyk JK, Reguła R, Bujak K, Fronczek M, Gonera M, Gawlita M, Wasilewski J, Lekston A, Kurek A, Gierlotka M, Trzeciak P, Hawranek M, Ostrowska Z, Wiczkowski A, Poloński L, Gąsior M
    Academic press:
    PLOS ONE (rok: 2016, tom: 11, strony: 45305), Wydawca: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pone.0150500 - link to the publication
  3. The platelet-to-lymphocyte ratio as a predictor of all-cause mortality in patients with coronary artery disease undergoing elective percutaneous coronary intervention and stent implantation
    Authors:
    Tadeusz Osadnik, Jarosław Wasilewski, Andrzej Lekston, Joanna Strzelczyk, Anna Kurek, Małgorzata Gonera, Marcin Gawlita, Rafał Reguła, Kamil Bujak, Bożena Szyguła-Jurkiewicz, Andrzej Wiczkowski, Lech Poloński
    Academic press:
    Journal of the Saudi Heart Association (rok: 2015, tom: 27, strony: 144-151), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jsha.2015.02.004 - link to the publication
  4. Comparison of modification of diet in renal disease and chronic kidney disease epidemiology collaboration formulas in predicting long-term outcomes in patients undergoing stent implantation due to stable coronary artery disease
    Authors:
    Osadnik T, Wasilewski J, Lekston A, Strzelczyk J, Kurek A, Gutowski AR, Dyrbuś K, Bujak K, Reguła R, Rozentryt P, Szyguła-Jurkiewicz B, Poloński L.
    Academic press:
    Clinical Research in Cardiology (rok: 2014, tom: 103, strony: 569-76), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00392-014-0687-1 - link to the publication
  5. Red cell distribution width is associated with long-term prognosis in patients with stable coronary artery disease
    Authors:
    Tadeusz Osadnik, Joanna Strzelczyk, Michał Hawranek, Andrzej Lekston, Jarosław Wasilewski, Anna Kurek, Aleksander Rafał Gutowski, Krzysztof Wilczek, Krzysztof Dyrbuś, Marek Gierlotka, Andrzej Wiczkowski, Mariusz Gąsior, Andrzej Szafranek, Lech Poloński
    Academic press:
    BMC Cardiovascular Disorders (rok: 2013, tom: 13, strony: 113), Wydawca: Jo Appleford-Cook
    Status:
    Published
    DOI:
    10.1186/1471-2261-13-113 - link to the publication
  6. Relationship of the rs1799752 polymorphism of the angiotensin-converting enzyme gene and the rs699 polymorphism of the angiotensinogen gene to the process of in-stent restenosis in a population of Polish patients with stable coronary artery disease.
    Authors:
    Osadnik T, Strzelczyk JK, Fronczek M, Bujak K, Reguła R, Gonera M, Gawlita M, Kurek A, Wasilewski J, Lekston A, Gierlotka M, Hawranek M, Ostrowska Z, Wiczkowski A, Poloński L, Gąsior M
    Academic press:
    Advances in Medical Sciences (rok: 2016, tom: 61, strony: 276-281), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.advms.2016.03.006 - link to the publication
  7. The Impact of Anemia on the Long-term Outcomes After Percutaneous Coronary Intervention and Stent Implantation in the Cohort of 2959 Patients
    Authors:
    adeusz Osadnik, Jaroslaw Wasilewski, Andrzej Lekston, Anna Kurek, Malgorzata Gonera, Marcin Gawlita, Marianna Janion, Michal Hawranek, Przemyslaw Trzeciak, Joanna Strzelczyk and Lech Polonsk
    Academic press:
    EXPERIMENTAL & CLINICAL CARDIOLOGY (rok: 2014, tom: 20, strony: 2097-2105), Wydawca: Academic Press
    Status:
    Published