Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Study on the mechanism of particulate guanylyl cyclase type A (GC-A) induction and its function in the regulation of inflammatory process by monocytes

2011/01/D/NZ3/04249

Keywords:

particulate guanylyl cyclase type A (GC-A) monocytes transcription factors Sp1 and NF-Y

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_7: Signal transduction

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Małgorzata Mitkiewicz 

Number of co-investigators in the project: 5

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 296 500 PLN

Project start date (Y-m-d): 2011-12-07

Project end date (Y-m-d): 2016-06-06

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Inkubator CO2 (30 000 PLN)
  2. Zbiornik do mrożenia w ciekłym azocie.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Struktura, regulacja oraz funkcje błonowej cyklazy guanylanowej typu A
    Authors:
    Mitkiewicz Małgorzata
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (rok: 2015, tom: 69, strony: 457-468), Wydawca: Instytut Immunologii i Terapii Doświadczalnej PAN
    Status:
    Published
    DOI:
    10.5604/17322693.1148746 - link to the publication
  2. Sp1 mediates phorbol ester (PMA)-induced expression of membrane-bound guanylyl cyclase GC-A in human monocytic THP-1 cells
    Authors:
    Mitkiewicz Małgorzata, Bac Bernadeta, Kuropatwa Marianna, Kurowska Ewa, Matuszyk Janusz, Siednienko Jakub
    Academic press:
    Acta Biochimica Polonica (rok: 2018, ), Wydawca: Polish Biochemical Society and of the Committee of Biochemistry and Biophysics Polish Academy of Sciences
    Status:
    Accepted for publication
    DOI:
    10.18388/abp.2017_2341 - link to the publication
  1. Induction of particulate guanylyl cyclase type A expression in monocytes
    Authors:
    Mitkiewicz M., Siednienko J., Zyzak J., Kuropatwa M., Kurowska E., Matuszyk J.
    Conference:
    BIO 2014 (1st Congress of the Polish Biochemistry, Cell Biology, Biophysics and Bioinformatics) w Warszawie (rok: 2014, ), Wydawca: Acta Biochimica Polonica
    Data:
    konferencja 9-12 września 2014
    Status:
    Published

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