Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Evaluation of the expression changes of the selected miRNA in TGF/SMAD signalling pathway regulation and on VEGF activation in lung sarcoidosis

2011/01/B/NZ5/04239

Keywords:

sarcoidosis microRNA VEGF TGFbeta signalling pathway lung diseases

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski, Zakład Molekularnych Podstaw Medycyny

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Ewa Brzeziańska-Lasota 

Number of co-investigators in the project: 6

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 412 810 PLN

Project start date (Y-m-d): 2011-12-05

Project end date (Y-m-d): 2014-12-04

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. zamrażarka niskotemperaturowa (43 700 PLN)
  2. urządzenie do rozdrabniania miękkich tkanek - Pellet Pestle z wyposażeniem (2 560 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Altered miRNA expression in pulmonary sarcoidosis
    Authors:
    Kiszałkiewicz J, Piotrowski WJ, Pastuszak-Lewandoska D, Górski P, Antczak A, Górski W, Domańska-Senderowska D, Migdalska-Sęk M, Czarnecka KH, Nawrot E, Brzeziańska-Lasota E
    Academic press:
    BMC Medical Genetics (rok: 2016, tom: 14, strony: 17-20), Wydawca: Sringer
    Status:
    Published
    DOI:
    10.1186/s12881-016-0266-6 - link to the publication
  2. Immunoexpression of TGF- β/Smad and VEGF-A proteins in serum and BAL fluid of sarcoidosis patients
    Authors:
    Piotrowski WJ, Kiszałkiewicz J, Górski P, Antczak A, Górski W, Pastuszak-Lewandoska D, Migdalska-Sęk M, Domańska-Senderowska D, Nawrot E, Czarnecka KH, Kurmanowska Z, Brzeziańska-Lasota E
    Academic press:
    BMC Immunology (rok: 2015, tom: 6, strony: 16-58), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1186/s12865-015-0123-y - link to the publication
  3. Expression of HIF-1A/VEGF/ING-4 axis in pulmonary sarcoidosis
    Authors:
    Piotrowski WJ, Kiszałkiewicz J, Pastuszak-Lewandoska D, Górski P, Antczak A, Migdalska-Sęk M, Górski W, Czarnecka KH, Domańska D, Nawrot E, Brzeziańska-Lasota E.
    Academic press:
    Advs Exp. Medicine, Biology - Neuroscience and Respiration (rok: 2015, tom: 866, strony: 61-69), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/5584_2015_144 - link to the publication
  4. TGF-β and SMADs mRNA Expression Levels in Pulmonary Sarcoidosis
    Authors:
    Piotrowski WJ, Kiszałkiewicz J, Pastuszak-Lewandoska D, Antczak A, Górski P, Migdalska-Sęk M, Górski W, Czarnecka K, Nawrot E, Domańska D, Brzeziańska-Lasota E.
    Academic press:
    Advs Exp. Medicine, Biology - Neuroscience and Respiration (rok: 2015, tom: 852, strony: 59-69), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/5584_2014_106. - link to the publication

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