Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Antiviral activity of novel acyclic phosphonate nucleoside analogues containing the 1,2,3-triazole moiety

2011/01/D/NZ4/01276

Keywords:

antiviral activity acyclic nucleoside analogues azidoalkylphosphonates 1,2,3-triazoles

Descriptors:

  • NZ4_16:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Iwona Głowacka 

Number of co-investigators in the project: 3

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2011-12-16

Project end date (Y-m-d): 2014-12-15

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Wyparka próżniowa wraz z pompą membranową.

Information in the final report

  • Publication in academic press/journals (5)
  1. Synthesis of a New Series of Phosphonylated 1,2,3-Triazoles as Acyclic Analogs of Ribavirin
    Authors:
    Iwona E. Głowacka, Jan Balzarini, Andrzej E. Wróblewski
    Academic press:
    Arch. Pharm. Chem. Life Sci. (rok: 2013, tom: 346, strony: 677-687), Wydawca: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
    Status:
    Published
    DOI:
    10.1002/ardp.201300156 - link to the publication
  2. Synthesis and biological evaluation of novel 1,2,3-triazolonucleotides
    Authors:
    Iwona E. Głowacka, Jan Balzarini, Andrzej E. Wróblewski
    Academic press:
    Arch. Pharm. Chem. Life Sci. (rok: 2013, tom: 346, strony: 278–291), Wydawca: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
    Status:
    Published
    DOI:
    10.1002/ardp.201200421 - link to the publication
  3. Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues
    Authors:
    Iwona E. Głowacka,* Jan Balzarini, Graciela Andrei, Robert Snoeck, Dominique Schols and Dorota G. Piotrowska
    Academic press:
    Bioorganic and Medicinal Chemistry (rok: 2014, tom: 22, strony: 3629-3641), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bmc.2014.05.020 - link to the publication
  4. The synthesis, antiviral, cytostatic and cytotoxic evaluation of a new series of acyclonucleotide analogues with a 1,2,3-triazole linker
    Authors:
    Iwona E. Głowacka, Jan Balzarini, Andrzej E. Wróblewski
    Academic press:
    European Journal of Medicinal Chemistry (rok: 2013, tom: 70, strony: 703-722), Wydawca: Elsevier Masson SAS.
    Status:
    Published
    DOI:
    10.057 - link to the publication
  5. Design, synthesis, antiviral and cytotoxic evaluation of novel phosphonylated 1,2,3-triazoles as acyclic nucleotide analogues
    Authors:
    Iwona E. Głowacka, Jan Balzarini, Andrzej E. Wróblewski
    Academic press:
    Nucleosides, Nucleotides and Nucleic Acids (rok: 2012, tom: 31, strony: 293-318), Wydawca: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/15257770.2012.662611 - link to the publication

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