Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Generation of knockouts of HMTR1 and HMTR2 genes in human somatic cells and functional analysis of cap1 and cap2 methyltransferases encoded by these genes

2011/01/N/NZ1/00211

Keywords:

hMTr1 hMTr2 knockout

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_7: Cell engineering
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Maria Werner 

Number of co-investigators in the project: 2

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2011-12-07

Project end date (Y-m-d): 2013-06-06

Project duration:: 18 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  1. Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation
    Authors:
    Miroslaw Smietanski, Maria Werner, Elzbieta Purta, Katarzyna H. Kaminska, Janusz Stepinski, Edward Darzynkiewicz, Marcin Nowotny, Janusz M. Bujnicki
    Academic press:
    Nature Communications (rok: 2013, tom: nie dotyczy, strony: nie dotyczy), Wydawca: Nature Publishing Group
    Status:
    Submitted