Structure-adrenolytic activity relationship among racemic and chiral analogues o

Structure-adrenolytic activity relationship among racemic and chiral analogues of 1-(1H-indol-4-iloksy)-3-(2-(2-metoksyfenoksy)etyloamino)propan-2-ol

2011/01/D/NZ4/01735

Keywords

Descriptors

NZ4_17: Farmakologia

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Marek Bednarski

Number of co-investigators in the project: 8

Call

SONATA 1 – announced on 2011-03-15

Amount awarded: 319 999 PLN
Project start date: 2011-12-15
Project end date: 2015-06-14
Project duration: 42 months (the same as in the proposal)
Project status: Project settled

Equipment purchased [PL]

Czytnik multidetekcyjny FLUOstar Optima. Cost: 60 000 PLN
Wirówka z chłodzeniem MPW-260R. Cost: 15 000 PLN
Wyparka R-210/V z pompą próżniową V-700. Cost: 25 000 PLN

Information in the final report

Publication in academic press/journals (2)

Antiarrhythmic activity in occlusion-reperfusion model of 1- (1H-indol-4-yloxy)-3-{[2-(2- methoxyphenoxy)ethyl]amino} propan-2-ol and its enantiomers.

Authors:
Marek Bednarski, Monika Otto, Magdalena Dudek, Agata Siwek, Małgorzata Zygmunt, Joanna Knutelska, Leszek Nowiński, Grażyna Groszek, Jacek Sapa

Academic press:
Clinical and Experimental Pharmacology and Physiology (year: 2016, volume: 43, pages: 81-87), Publisher: Wiley Publishing Asia

Status:
Published

DOI:
10.1111/1440-1681.12491 – link to the publication
SYNTHESIS AND PHARMACOLOGICAL ACTIVITY NEW SERIES OF 1-(1H-INDOL-4-YLOXY)-3-(2-(2-METHOXYPHENOXY)ETHYLAMINO) PROPAN-2-OL ANALOGS

Authors:
Marek Bednarski, Monika Otto, Grażyna Groszek, Elżbieta Maziarz, Piotr Wilk, Jacek Sapa

Academic press:
Archiv der Pharmazie (year: 2016, volume: 349, pages: 211-223), Publisher: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Status:
Published

DOI:
10.1002/ardp.201500234 – link to the publication

Articles in post-conference publications (1)

Synthesis and pharmacological activity new series of 1-(1H-indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol analogs

Authors:
Marek Bednarski, Monika Otto, Leszek Nowiński, Katarzyna Raźny, Klaudia Lustyk, Grażyna Groszek

Conference:
1st Central European Biomedical Congress (year: 2014, pages: 104), Publisher: ZOZ Ośrodek UMEA Shinoda-Kuracejo

Date:
conference 16-20 lipca

Status:
Published

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