Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Structure-adrenolytic activity relationship among racemic and chiral analogues of 1-(1H-indol-4-iloksy)-3-(2-(2-metoksyfenoksy)etyloamino)propan-2-ol

2011/01/D/NZ4/01735

Keywords:

adrenolytics cardivascular antioxidant activity synthesis enantiomers

Descriptors:

  • NZ4_17:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marek Bednarski 

Number of co-investigators in the project: 8

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 319 999 PLN

Project start date (Y-m-d): 2011-12-15

Project end date (Y-m-d): 2015-06-14

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Czytnik multidetekcyjny FLUOstar Optima (60 000 PLN)
  2. Wyparka R-210/V z pompą próżniową V-700 (25 000 PLN)
  3. Wirówka z chłodzeniem MPW-260R (15 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Antiarrhythmic activity in occlusion-reperfusion model of 1- (1H-indol-4-yloxy)-3-{[2-(2- methoxyphenoxy)ethyl]amino} propan-2-ol and its enantiomers.
    Authors:
    Marek Bednarski, Monika Otto, Magdalena Dudek, Agata Siwek, Małgorzata Zygmunt, Joanna Knutelska, Leszek Nowiński, Grażyna Groszek, Jacek Sapa
    Academic press:
    Clinical and Experimental Pharmacology and Physiology (rok: 2016, tom: 43, strony: 81-87), Wydawca: Wiley Publishing Asia
    Status:
    Published
    DOI:
    10.1111/1440-1681.12491 - link to the publication
  2. SYNTHESIS AND PHARMACOLOGICAL ACTIVITY NEW SERIES OF 1-(1H-INDOL-4-YLOXY)-3-(2-(2-METHOXYPHENOXY)ETHYLAMINO) PROPAN-2-OL ANALOGS
    Authors:
    Marek Bednarski, Monika Otto, Grażyna Groszek, Elżbieta Maziarz, Piotr Wilk, Jacek Sapa
    Academic press:
    Archiv der Pharmazie (rok: 2016, tom: 349, strony: 211-223), Wydawca: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
    Status:
    Published
    DOI:
    10.1002/ardp.201500234 - link to the publication
  1. Synthesis and pharmacological activity new series of 1-(1H-indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol analogs
    Authors:
    Marek Bednarski, Monika Otto, Leszek Nowiński, Katarzyna Raźny, Klaudia Lustyk, Grażyna Groszek
    Conference:
    1st Central European Biomedical Congress (rok: 2014, ), Wydawca: ZOZ Ośrodek UMEA Shinoda-Kuracejo
    Data:
    konferencja 16-20 lipca
    Status:
    Published

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