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Molecular mechanisms involved in the neuroimmune dysregulation of allergic diseases in children

2011/01/D/NZ5/02771

Keywords

Descriptors

  • NZ5_3: Patogeneza chorób człowieka
  • NZ2_2: Genomika, transkryptomika i epigenomika
  • NZ1_1: Biologia molekularna

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Aleksandra Maria Szczepankiewicz

Number of co-investigators in the project: 9

Call

SONATA 1 – announced on 2011-03-15

Amount awarded
462 800 PLN
Project start date
2011-12-06
Project end date
2015-12-05
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. blok mikrofluidowy. Cost: 80 000 PLN
  2. wirówka bez chłodzenia z rotorem horyzontalnym. Cost: 30 000 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Polymorphisms in the interleukin 4, interleukin 4 receptor and interleukin 13 genes and allergic phenotype: A case control study

    Authors:
    Beata Narożna, Aleksandra Hoffmann, Paulina Sobkowiak, Natalia Schoneich, Anna Bręborowicz, Aleksandra Szczepankiewicz
    Academic press:
    Advances in Medical Sciences (year: 2016, volume: 61, pages: 40-45), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.advms.2015.07.003 – link to the publication

  2. Neurotrophin serum concentrations and polymorphisms of neurotrophins and their receptors in children with asthma

    Authors:
    Aleksandra Szczepankiewicz, Marta Rachel, Paulina Sobkowiak, Zdzislawa Kycler, Irena Wojsyk-Banaszak, Natalia Schoneich, Aleksandra Szczawinska-Poplonyk, Anna Breborowicz
    Academic press:
    Respiratory Medicine (year: 2013, volume: 107, pages: 30-36), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.rmed.2012.09.024 – link to the publication

Articles in post-conference publications (6)

  1. Altered expression of histamine receptor 4 and MAPK kinase in childhood asthma

    Authors:
    Aleksandra Szczepankiewicz, Paulina Sobkowiak, Aleksandra Hoffmann, Beata Narozna, Anna Breborowicz
    Conference:
    25 Kongres Europejskiego Towarzystwa Oddechowego (ERS) (year: 2015, pages: 46 (suppl 59)), Publisher: European Respiratory Journal
    Date:
    conference 26-30.09.2015
    Status:
    Published
    DOI:
    link to the publication

  2. Analysis of pro-BDNF and BDNF level in pediatric patients with atopic dermatitis and allergic rhinitis

    Authors:
    Szczepankiewicz, A; Sobkowiak, P; Narozna, B; Jenerowicz, D; Breborowicz, A.
    Conference:
    34 Kongres Europejskiej Akademii Alergologii i Immunologii Klinicznej (EAACI) (year: 2015, pages: 297), Publisher: Allergy
    Date:
    conference 06-10.06.2015
    Status:
    Published
    DOI:
    link to the publication

  3. NO CORRELATION BETWEEN CHILDHOOD ASTHMA AND LEPTIN AND LEPTIN RECEPTOR SERUM LEVELS

    Authors:
    Narozna B, Sobkowiak P, Schoneich N, Bręborowicz A, Szczepankiewicz A.
    Conference:
    XIV Międzynarodowy Kongres Pulmonologii Dziecięcej (CIPP) (year: 2015, pages: S56), Publisher: Pediatric Pulmonology
    Date:
    conference 25-28.06.2015
    Status:
    Published
    DOI:
    link to the publication

  4. ALTERED EXPRESSION OF THREE NEUROGENIC PATHWAY GENES DURING ASTHMA EXACERBATION IN PEDIATRIC PATIENTS

    Authors:
    Sobkowiak P, Hoffmann A, Narozna B, Breborowicz A, Szczepankiewicz A.
    Conference:
    XIV Międzynarodowy Kongres Pulmonologii Dziecięcej (CIPP) (year: 2015, pages: S79), Publisher: Pediatric Pulmonology
    Date:
    conference 25-28.06.2015
    Status:
    Published
    DOI:
    link to the publication

  5. Interleukin 4 affects fat tissue metabolism and expression of pro-inflammatory factors in isolated rat adipocytes

    Authors:
    Dawid Szczepankiewicz, Ewa Pruszynska-Oszmalek, Marek Skrzypski, Krzysztof W. Nowak, Aleksandra Szczepankiewicz
    Conference:
    International Symposium on Molecular Allergology (year: 2016, pages: 73), Publisher: Clinical and Translational Allergy
    Status:
    Accepted for publication

  6. Expression of histamine metabolizing enzymes is increased in allergic children

    Authors:
    Aleksandra Szczepankiewicz, Paulina Sobkowiak, Marta Rachel, Beata Narozna, Dorota Jenerowicz, Witold Swiatowy, Anna Breborowicz
    Conference:
    International Symposium on Molecular Allergology (year: 2016, pages: 77), Publisher: Clinical and Translational Allergy
    Status:
    Accepted for publication

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