Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular mechanisms involved in the neuroimmune dysregulation of allergic diseases in children

2011/01/D/NZ5/02771

Keywords:

asthma allergy neurotrophins neurogenic inflammation gene expression

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ1_1: Molecular biology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Aleksandra Szczepankiewicz 

Number of co-investigators in the project: 9

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 462 800 PLN

Project start date (Y-m-d): 2011-12-06

Project end date (Y-m-d): 2015-12-05

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. blok mikrofluidowy (80 000 PLN)
  2. wirówka bez chłodzenia z rotorem horyzontalnym (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (6)
  1. Polymorphisms in the interleukin 4, interleukin 4 receptor and interleukin 13 genes and allergic phenotype: A case control study
    Authors:
    Beata Narożna, Aleksandra Hoffmann, Paulina Sobkowiak, Natalia Schoneich, Anna Bręborowicz, Aleksandra Szczepankiewicz
    Academic press:
    Advances in Medical Sciences (rok: 2016, tom: 61, strony: 40-45), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.advms.2015.07.003 - link to the publication
  2. Increased expression of neurogenic inflammation genes in childhood atopic asthma but not in allergic rhinitis
    Authors:
    Paulina Sobkowiak, Irena Wojsyk-Banaszak, Marta Rachel, Witold Światowy, Beata Narozna, Dawid Szczepankiewicz, Anna Bręborowicz, Aleksandra Szczepankiewicz
    Academic press:
    Asthma, Allergy and Immunology Research (rok: 2016, tom: brak, strony: brak), Wydawca: Korean Academy of Asthma, Allergy and Clinical Immunology
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. Neurotrophin serum concentrations and polymorphisms of neurotrophins and their receptors in children with asthma
    Authors:
    Aleksandra Szczepankiewicz, Marta Rachel, Paulina Sobkowiak, Zdzislawa Kycler, Irena Wojsyk-Banaszak, Natalia Schoneich, Aleksandra Szczawinska-Poplonyk, Anna Breborowicz
    Academic press:
    Respiratory Medicine (rok: 2013, tom: 107, strony: 30-36), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.rmed.2012.09.024 - link to the publication
  1. ALTERED EXPRESSION OF THREE NEUROGENIC PATHWAY GENES DURING ASTHMA EXACERBATION IN PEDIATRIC PATIENTS
    Authors:
    Sobkowiak P, Hoffmann A, Narozna B, Breborowicz A, Szczepankiewicz A.
    Conference:
    XIV Międzynarodowy Kongres Pulmonologii Dziecięcej (CIPP) (rok: 2015, ), Wydawca: Pediatric Pulmonology
    Data:
    konferencja 25-28.06.2015
    Status:
    Published
    DOI:
    link to the publication
  2. Analysis of pro-BDNF and BDNF level in pediatric patients with atopic dermatitis and allergic rhinitis
    Authors:
    Szczepankiewicz, A; Sobkowiak, P; Narozna, B; Jenerowicz, D; Breborowicz, A.
    Conference:
    34 Kongres Europejskiej Akademii Alergologii i Immunologii Klinicznej (EAACI) (rok: 2015, ), Wydawca: Allergy
    Data:
    konferencja 06-10.06.2015
    Status:
    Published
    DOI:
    link to the publication
  3. NO CORRELATION BETWEEN CHILDHOOD ASTHMA AND LEPTIN AND LEPTIN RECEPTOR SERUM LEVELS
    Authors:
    Narozna B, Sobkowiak P, Schoneich N, Bręborowicz A, Szczepankiewicz A.
    Conference:
    XIV Międzynarodowy Kongres Pulmonologii Dziecięcej (CIPP) (rok: 2015, ), Wydawca: Pediatric Pulmonology
    Data:
    konferencja 25-28.06.2015
    Status:
    Published
    DOI:
    link to the publication
  4. Altered expression of histamine receptor 4 and MAPK kinase in childhood asthma
    Authors:
    Aleksandra Szczepankiewicz, Paulina Sobkowiak, Aleksandra Hoffmann, Beata Narozna, Anna Breborowicz
    Conference:
    25 Kongres Europejskiego Towarzystwa Oddechowego (ERS) (rok: 2015, ), Wydawca: European Respiratory Journal
    Data:
    konferencja 26-30.09.2015
    Status:
    Published
    DOI:
    link to the publication
  5. Interleukin 4 affects fat tissue metabolism and expression of pro-inflammatory factors in isolated rat adipocytes
    Authors:
    Dawid Szczepankiewicz, Ewa Pruszynska-Oszmalek, Marek Skrzypski, Krzysztof W. Nowak, Aleksandra Szczepankiewicz
    Conference:
    International Symposium on Molecular Allergology (rok: 2016, ), Wydawca: Clinical and Translational Allergy
    Data:
    konferencja 19-21.11.2015
    Status:
    Accepted for publication
  6. Expression of histamine metabolizing enzymes is increased in allergic children
    Authors:
    Aleksandra Szczepankiewicz, Paulina Sobkowiak, Marta Rachel, Beata Narozna, Dorota Jenerowicz, Witold Swiatowy, Anna Breborowicz
    Conference:
    International Symposium on Molecular Allergology (rok: 2016, ), Wydawca: Clinical and Translational Allergy
    Data:
    konferencja 19-21.11.2015
    Status:
    Accepted for publication

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