Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Analyses of the interactions between prostate cancer, immune and endothelial cells within 'metastatic cell niche"

2011/01/B/NZ3/00004

Keywords:

cancer prostate invasion cell migration connexins cell-cell interactions monocyte niche

Descriptors:

  • NZ3_1: Cell biology
  • NZ4_11: Metabolism
  • NZ3_7: Signal transduction

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

UNIWERSYTET JAGIELLOŃSKI

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Jarosław Czyż 

Number of co-investigators in the project: 7

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 361 000 PLN

Project start date (Y-m-d): 2011-12-07

Project end date (Y-m-d): 2014-12-06

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. ____.
  2. Komputer (5 050 PLN)

Information in the final report

  • Publication in academic press/journals (9)
  1. Antioxidant and anticancer activities of Chenopodium quinoa leaves extracts - in vitro study.
    Authors:
    Gawlik-Dziki U, Świeca M, Sułkowski M, Dziki D, Baraniak B, Czyż J.
    Academic press:
    Food Chem Toxicol (rok: 2013, tom: 57, strony: 154-60), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fct.2013.03.023 - link to the publication
  2. The role of connexins in prostate cancer promotion and progression
    Authors:
    Czyż Jarosław, Szpak Katarzyna, Madeja Zbigniew
    Academic press:
    Nature Reviews Urology (rok: 2012, tom: 9(5), strony: 274-82), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/nrurol.2012.14 - link to the publication
  3. Fenofibrate enhances barrier function of endothelial continuum within the metastatic niche of prostate cancer cells
    Authors:
    Piwowarczyk K, Wybieralska E, Baran J, Borowczyk J, Rybak P, Kosińska M, Włodarczyk AJ, Michalik M, Siedlar M, Madeja Z, Dobrucki J, Reiss K, Czyż J.
    Academic press:
    Expert Opin Ther Targets (rok: 2014, tom: Ahead of print, strony: 45305), Wydawca: Informa
    Status:
    Published
    DOI:
    10.1517/14728222.2014.981153 - link to the publication
  4. Functional links between Snail-1 and Cx43 account for the recruitment of Cx43-positive cells into the invasive front of prostate cancer
    Authors:
    Ryszawy D, Sarna M, Rak M, Szpak K, Kędracka-Krok S, Michalik M, Siedlar M, Zuba-Surma E, Burda K, Korohoda W, Madeja Z, Czyż J.
    Academic press:
    Carcinogenesis (rok: 2014, tom: 5(9), strony: 1920-30), Wydawca: Oxford
    Status:
    Published
    DOI:
    10.1093/carcin/bgu033 - link to the publication
  5. Triterpene saponosides from Lysimachia ciliata differentially attenuate invasive potential of prostate cancer cells
    Authors:
    Koczurkiewicz P, Podolak I, Skrzeczyńska-Moncznik J, Sarna M, Wójcik KA, Ryszawy D, Galanty A, Lasota S, Madeja Z, Czyż J, Michalik M
    Academic press:
    Chem Biol Interact (rok: 2013, tom: 206(1), strony: 45460), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cbi.2013.08.003 - link to the publication
  6. Effect of bioaccessibility of phenolic compounds on in vitro anticancer activity of broccoli sprouts
    Authors:
    Gawlik-Dziki, U. , Jezyna, M., Świeca, M., Dziki, D., Baraniak, B., Czyz, J.
    Academic press:
    Food Research International (rok: 2012, tom: 49, strony: 469-476), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.foodres.2012.08.010 - link to the publication
  7. Morpho-physiological heterogeneity of cells within two rat prostate carcinoma cell lines AT-2 and MAT-LyLu differing in the degree of malignancy observed by cell cloning and the effects of caffeine, theophylline and papaverine upon a proportion of the clones
    Authors:
    Musialik E, Ryszawy D, Madeja Z, Korohoda W.
    Academic press:
    Oncol Rep. (rok: 2013, tom: 29(5), strony: 1789-96), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/or.2013.2323 - link to the publication
  8. Lithium Attenuates TGF-β(1)-Induced Fibroblasts to Myofibroblasts Transition in Bronchial Fibroblasts Derived from Asthmatic Patients
    Authors:
    Michalik M, Wójcik KA, Jakieła B, Szpak K, Pierzchalska M, Sanak M, Madeja Z, Czyż J
    Academic press:
    J Allergy (rok: 2012, tom: 206109, strony: 45303), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2012/206109 - link to the publication
  9. Lovastatin-induced decrease of intracellular cholesterol level attenuates fibroblast-to-myofibroblast transition in bronchial fibroblasts derived from asthmatic patients.
    Authors:
    Michalik M, Soczek E, Kosińska M, Rak M, Wójcik KA, Lasota S, Pierzchalska M, Czyż J, Madeja Z
    Academic press:
    Eur J Pharmacol. (rok: 2013, tom: 704, strony: 23-32), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejphar.2013.02.023 - link to the publication