Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Establishing of a pyrosequencing pipeline for DNA methylation analysis.

2011/01/D/NZ2/00095

Keywords:

DNA methylation pirosequencing tumor supressor genes tumor genetics

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_1: Molecular genetics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Genetyki Człowieka PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Maciej Giefing 

Number of co-investigators in the project: 3

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 890 500 PLN

Project start date (Y-m-d): 2011-12-06

Project end date (Y-m-d): 2014-12-05

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Miniwirówka, BIONOVO (1 000 PLN)
  2. Termocykler, BIO-RAD (40 000 PLN)
  3. Urządzenie do ciągłego monitoringu hodowli komórkowych (69 467 PLN)
  4. Vortex (1 000 PLN)
  5. Komora PCR, POLGEN (8 000 PLN)
  6. Lodówko-zamrażarka, EURO-NET (2 000 PLN)
  7. System do sekwencjonowania, SYNGEN (344 000 PLN)
  8. Zestaw pipet oraz drobny sprzęt laboratoryjny (14 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Book publications / chapters in book publications (1)
  1. Recurrent epigenetic silencing of the PTPRD tumor suppressor in laryngeal squamous cell carcinoma
    Authors:
    Szaumkessel M, Wojciechowska S, Janiszewska J, Zemke N, Byzia E, Kiwerska K, Kostrzewska-Poczekaj M, Ustaszewski A, Jarmuż-Szymczak M, Grenman R, Wierzbicka M, Bartochowska A, Szyfter K, and Giefing M.
    Academic press:
    Tumor Biology (tom: -, strony: -), Wydawca: Springer
    Status:
    Accepted for publication
  2. The PRDX2 gene is transcriptionally silenced and de novo methylated in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma.
    Authors:
    Schneider M, Szaumkessel M, Richter J, Ammerpohl O, Hansmann ML, Küppers R, Siebert R, Giefing M.
    Academic press:
    Blood (rok: 2014, tom: 123, strony: 3672-3674), Wydawca: American Society of Hematology (United States)
    Status:
    Published
    DOI:
    10.1182/blood-2014-02-553263 - link to the publication
  1. Metoda pirosekwencjonowania w badaniu nowotworów.
    Authors:
    Byzia E, Giefing M.
    Book:
    Na Pograniczu Chemii i Biologii (rok: 2014, tom: XXXII, strony: 205-223), Wydawca: Wydawnictwo Naukowe Uniwersytetu Adama Mickiewicza w Poznaniu.
    Status:
    Published