Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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4PYRAD - endogenous NAD analogue an ally or competitor

2011/01/B/NZ1/01629

Keywords:

NAD 4PYRAD,nicotinamide nicotinamide riboside

Descriptors:

  • NZ1_2: Biochemistry
  • NZ3_1: Cell biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Lekarski

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Słomińska 

Number of co-investigators in the project: 6

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 596 500 PLN

Project start date (Y-m-d): 2011-12-06

Project end date (Y-m-d): 2016-03-05

Project duration:: 51 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. komputer przenośny (5 812 PLN)
  2. system wysokosprawnej chromatografii cieczowej dwuwymiarowej (200 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. 4-PYRIDONE-3-CARBOXAMIDE RIBOSIDE (4PYR) METABOLISM IN ENDOTHELIAL CELLS AND ITS IMPACT ON CELLULAR ENERGETIC BALANCE
    Authors:
    Iwona Pelikant-Małecka, Alicja Sielicka, Ewa Kaniewska, Ryszard T. Smolenski,Ewa M. Slominska
    Academic press:
    Nucleosides, Nucleotides and Nucleic Acids (rok: 2014, tom: 33, strony: 338-341), Wydawca: Taylor&Francis
    Status:
    Published
    DOI:
    10.1080/15257770.2014.889303 - link to the publication
  2. Endothelial toxicity of unusual nucleotide metabolites
    Authors:
    Iwona Pelikant-Malecka
    Academic press:
    Pharmacological Report (rok: 2015, tom: 67(4), strony: 818-22), Wydawca: POLISH ACAD SCIENCES INST PHARMACOLOGY
    Status:
    Published
    DOI:
    10.1016/j.pharep.2015.03.020. - link to the publication
  3. IN VITRO AND CELLULAR EFFECTS OF 4-PYRIDONE-3-CARBOXAMIDE RIBOSIDE (4PYR) ON ENZYMES OF NUCLEOTIDE METABOLISM
    Authors:
    Ewa M. Slominska, Tomasz Borkowski, Iwona Rybakowska, Magdalena Abramowicz-Glinka, Czesława Orlewska, Ryszard T. Smolenski
    Academic press:
    Nucleosides, Nucleotides and Nucleic Acids (rok: 2014, tom: 33, strony: 353-357), Wydawca: Taylor&Francis
    Status:
    Published
    DOI:
    10.1080/15257770.2014.889304 - link to the publication
  4. EFFECT OF 4-PYRIDONE-3-CARBOXAMIDE RIBOSIDE (4PYR)- POTENCTIAL CARDIOVASCULAR TOXIN IN PERFUSED RAT HEART
    Authors:
    Pawel Romaszko, Ewa M. Slominska, Ryszard T. Smolenski
    Academic press:
    Nucleosides, Nucleotides and Nucleic Acids (rok: 2014, tom: 33, strony: 333-337), Wydawca: Taylor&Francis
    Status:
    Published
    DOI:
    10.1080/15257770.2013.872793 - link to the publication

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