Projects funded by the NCN
Can extracts from Epilobium sp. inhibit proliferation of prostate cell LNCaP by influencing the activity of histone acetylotransferase (HAT)?
2011/01/D/NZ4/01262
Keywords:
Epilobium oenothein B polyphenols urolithins prostate cancer prostatic hyperplasia PSA histone acetyltranferase inhibitors
Descriptors:
- NZ4_16:
Panel:
NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution :
Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 4
Call: SONATA 1 - announced on 2011-03-15
Amount awarded: 174 000 PLN
Project start date (Y-m-d): 2011-12-16
Project end date (Y-m-d): 2014-12-15
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- -.
Information in the final report
- Publication in academic press/journals (2)
- Extracts from Epilobium sp. herbs induce apoptosis in human hormone-dependent prostate cancer cells by activating mitochondrial pathway.Authors:Stolarczyk M, Naruszewicz M, Kiss AKAcademic press:Journal of Pharmacy and Pharmacology (rok: 2013, tom: 65, strony: 1044-1054), Wydawca: Royal Pharmaceutical SocietyStatus:PublishedDOI:10.1111/jphp.12063 - link to the publication
- Extracts from Epilobium sp. herbs, their components and gut microbiota metabolites of Epilobium ellagitannins-urolithins inhibit hormone-dependemt prostate cancer cells (LNCaP) proliferation and PSA secretion.Authors:Stolarczyk M, Piwowarski JP, Granica S, Stefańska J, Naruszewicz M, Kiss AK.Academic press:Phytotherapy Research (rok: 2013, tom: 27, strony: 1842-1848), Wydawca: John Wiley & SonsStatus:PublishedDOI:10.1002/ptr.4941 - link to the publication