Can extracts from Epilobium sp. inhibit proliferation of prostate cell LNCaP by influencing the activity of histone acetylotransferase (HAT)?

2011/01/D/NZ4/01262

Keywords

Descriptors

  • NZ4_16: Farmacja

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Anna Karolina Kiss

Number of co-investigators in the project: 4

Call

SONATA 1 – announced on 2011-03-15

Amount awarded
174 000 PLN
Project start date
2011-12-16
Project end date
2014-12-15
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. -.

Information in the final report

Publication in academic press/journals (2)

  1. Extracts from Epilobium sp. herbs induce apoptosis in human hormone-dependent prostate cancer cells by activating mitochondrial pathway.

    Authors:
    Stolarczyk M, Naruszewicz M, Kiss AK
    Academic press:
    Journal of Pharmacy and Pharmacology (year: 2013, volume: 65, pages: 1044-1054), Publisher: Royal Pharmaceutical Society
    Status:
    Published
    DOI:
    10.1111/jphp.12063 – link to the publication
  2. Extracts from Epilobium sp. herbs, their components and gut microbiota metabolites of Epilobium ellagitannins-urolithins inhibit hormone-dependemt prostate cancer cells (LNCaP) proliferation and PSA secretion.

    Authors:
    Stolarczyk M, Piwowarski JP, Granica S, Stefańska J, Naruszewicz M, Kiss AK.
    Academic press:
    Phytotherapy Research (year: 2013, volume: 27, pages: 1842-1848), Publisher: John Wiley & Sons
    Status:
    Published
    DOI:
    10.1002/ptr.4941 – link to the publication

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