Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Structural and functional characterization of novel non-coding RNAs from Helicobacter pylori

2011/01/D/NZ1/00212

Keywords:

non-coding RNA RNA crystallography

Descriptors:

  • NZ1_4: Structural biology
  • NZ2_7: Bioinformatics
  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Grzegorz Chojnowski 

Number of co-investigators in the project: 5

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 550 000 PLN

Project start date (Y-m-d): 2011-12-06

Project end date (Y-m-d): 2015-09-05

Project duration:: 45 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Licencja na oprogramowanie do wirtualizacji obliczeń (6 000 PLN)
  2. Rozbudowa macierzy do przechowywania bardzo dużej ilości danych: półka dyskowa z 12 dyskami (co najmniej 2TB pojemności). (35 000 PLN)
  3. Serwer do do udostępnienia danych wykonany w technologii blade: platforma z co najmniej 2CPU z 4G RAM na rdzeń i dyskami SSD (25 000 PLN)
  4. Serwer do wielkoskalowych obliczeń krystalograficznych (analizy map gęstości elektronowej) wykonany w technologii blade: platforma z co najmniej 4CPU z 4G RAM na rdzeń i dyskami SSD (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Brickworx builds recurrent RNA and DNA structural motifs into medium- and low-resolution electron-density maps
    Authors:
    Grzegorz Chojnowski, Tomasz Waleń, Paweł Piątkowski, Wojciech Potrzebowski, Janusz M. Bujnicki
    Academic press:
    Acta Crystallographica Section D Biological Crystallography (rok: 2015, tom: 71, strony: 697-705), Wydawca: Wiley-Blackwell
    Status:
    Published
    DOI:
    10.1107/S1399004715000383 - link to the publication
  2. ClaRNA: a classifier of contacts in RNA 3D structures based on a comparative analysis of various classification schemes
    Authors:
    Tomasz Waleń, Grzegorz Chojnowski, Przemysław Gierski, Janusz M. Bujnicki
    Academic press:
    Nucleic Acids Research (rok: 2014, tom: 42, strony: e151), Wydawca: Oxford Journals
    Status:
    Published
    DOI:
    10.1093/nar/gku765 - link to the publication
  3. Computational modeling of RNA 3D structures, with the aid of experimental restraints.
    Authors:
    Marcin Magnus, Dorota Matelska, Grzegorz Lach, Grzegorz Chojnowski, Michal J Boniecki, Elzbieta Purta, Wayne Dawson, Stanislaw Dunin-Horkawicz, Janusz M Bujnicki
    Academic press:
    RNA biology (rok: 2014, tom: 11, strony: 522-536), Wydawca: Taylor & Francis
    Status:
    Published
    DOI:
    10.4161/rna.28826 - link to the publication
  4. Computational modeling of protein–RNA complex structures
    Authors:
    Tuszynska, I., Matelska, D., Magnus, M., Chojnowski, G., Kasprzak, J. M., Kozlowski, L. P., Bujnicki, J. M.
    Academic press:
    Methods (rok: 2013, tom: 65(3), strony: 310-9), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ymeth.2013.09.014 - link to the publication
  5. RNA Bricks—a database of RNA 3D motifs and their interactions
    Authors:
    Grzegorz Chojnowski, Tomasz Waleń, Janusz M. Bujnicki
    Academic press:
    Nucleic Acids Research (rok: 2014, tom: 42, strony: D123-D131), Wydawca: Oxford Journals
    Status:
    Published
    DOI:
    10.1093/nar/gkt1084 - link to the publication