Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The expression of complement inhibitors in ovarian and corpus uteri cancers - a new perspective for immunotherapy

2011/01/D/NZ7/04688

Keywords:

complement system ovarian cancer corpus uteri cancer CD55 CD59 factor H factor H-like complement inhibitors immunotherapy IL-6 IL-8

Descriptors:

  • NZ7_1: Epidemiology
  • NZ7_4: Prevention in population health

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Wyższa Szkoła Informatyki i Zarządzania w Rzeszowie, Wydział Turystyki i Nauk o Zdrowiu

woj. podkarpackie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Lucyna Kapka-Skrzypczak 

Number of co-investigators in the project: 8

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 468 500 PLN

Project start date (Y-m-d): 2011-12-07

Project end date (Y-m-d): 2014-12-06

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Laptop (5 000 PLN)
  2. Rotator (2 500 PLN)
  3. Kołyska laboratoryjna (3 000 PLN)
  4. Zestaw do elektrotransferu półsuchego (2 053 PLN)
  5. Zestaw do elektroforezy pionowej (2 149 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (4)
  1. Effect of IL-6 and IL-8 on the expression of the complement activation inhibitors MAC-inhibitory protein and decay-accelerating factor in ovarian cancer A2780 cells
    Authors:
    Kapka-Skrzypczak L, Popek S, Sawicki K, Wolińska E, Czajka M, Skrzypczak M
    Academic press:
    Oncology Letters (rok: 2016, tom: 12, strony: 1507-1512), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    brak - link to the publication
  2. CD55, CD59, factor H and factor H-like 1 gene expression analysis intumors of the ovary and corpus uteri origin
    Authors:
    Kapka-Skrzypczak L, Wolińska E, Szparecki G, Wilczyński GM, Czajka M, Skrzypczak M
    Academic press:
    Immunology Letters (rok: 2015, tom: 167, strony: 67-71), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.imlet.2015.06.017 - link to the publication
  3. The immunohistochemical analysis of membrane-bound CD55, CD59 and fluid-phase FH and FH-like complement inhibitors in cancers of ovary and corpus uteri origin
    Authors:
    Kapka-Skrzypczak L, Wolińska E, Szparecki G, Czajka M, Skrzypczak M
    Academic press:
    Central European Journal of Immunology (rok: 2015, tom: 40(3), strony: 349-353), Wydawca: Polish Society of Experimental and Clinical Immunology
    Status:
    Published
    DOI:
    10.5114/ceji.2015.54598 - link to the publication
  4. Estrogen Receptors Co-activation Mechanisms
    Authors:
    Skrzypczak M, Kapka-Skrzypczak L, Cyranka M, Treeck O, Wróbel A, Matosiuk D.
    Academic press:
    Current Medicinal Chemistry (rok: 2013, tom: Vol. 20, No. 27, strony: 3317-38.), Wydawca: BENTHAM SCIENCE PUBL LTD
    Status:
    Published
    DOI:
    10.2174/09298673113209990006 - link to the publication
  5. IL‑6 and IL‑8 enhance factor H binding to the cell membranes
    Authors:
    Popek S, Kapka-Skrzypczak L, Sawicki K, Wolińska E, Skrzypczak M, Czajka M
    Academic press:
    Molecular Medicine Reports (rok: 2016, tom: 13, strony: 3886-3894), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/mmr.2016.5012 - link to the publication
  1. The evaluation of the role of IL-6 and IL-8 in the complement inhibitors expression with ovarian carcinoma established cell line non-producing interleukine-6 (A2780), but IL-6 receptor positive
    Authors:
    Kapka-Skrzypczak L, Popek S, Wilczek E, Wilczyński G, Skrzypczak M
    Conference:
    14th World Congress on Menopause (rok: 2014, ), Wydawca: International Menopause Society
    Data:
    konferencja 01-04.05.2014
    Status:
    Published
  2. The expression and tissue localization of complement inhibitors in cancer of ovary and corpus uteri origin
    Authors:
    Skrzypczak M, Wilczek E, Wilczyński G, Niedźwiecka J, Sawicki K, Kapka-Skrzypczak L.
    Conference:
    The 23rd Asian and Oceanic Congress of Obstetrics and Gynaecology (23rd AOCOG 2013) (rok: 2013, ), Wydawca: The Royal Thai College of Obstetricians & Gynaecologists
    Data:
    konferencja 20-23.10.2013
    Status:
    Published
  3. The expression of complement inhibitors in ovarian and corpus uteri cancers - a new perspective for immunotherapy
    Authors:
    Skrzypczak M, Wilczek E, Wilczyński G, Popek S, Sawicki K, Czajka M, Kapka-Skrzypczak L
    Conference:
    14th World Congress on Menopause (rok: 2014, ), Wydawca: International Menopause Society
    Data:
    konferencja 01-04.05.2014
    Status:
    Published
  4. Expression of factor H in ovarian cancer tissue detected by immunohistochemistry
    Authors:
    Kapka-Skrzypczak L, Wilczek E, Wilczyński G, Popek S, Skrzypczak M
    Conference:
    The 23rd Asian and Oceanic Congress of Obstetrics and Gynaecology (23rd AOCOG 2013) (rok: 2013, ), Wydawca: The Royal Thai College of Obstetricians & Gynaecologists
    Data:
    konferencja 20-23.10.2013
    Status:
    Published

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